KEGG   DRUG: Brompheniramine maleateHelp
Entry
D00663                      Drug                                   

Name
Brompheniramine maleate (USAN);
Dimetane (TN)
Formula
C16H19BrN2. C4H4O4
Exact mass
434.0841
Mol weight
435.3116
Structure
Mol fileKCF fileDB search
Simcomp SIMCOMP
Class
Anti-allergic agent
 DG01557  Histamine receptor antagonist
  DG01482  Histamine receptor H1 antagonist
Remark
ATC code: R06AB01
Chemical structure group: DG01097
Efficacy
Antiallergic, H1 receptor antagonist
Target
HRH1 [HSA:3269] [KO:K04149]
  Pathway
hsa04080  Neuroactive ligand-receptor interaction
hsa04750  Inflammatory mediator regulation of TRP channels
Interaction
Drug interaction
Structure map
map07212  Histamine H1 receptor antagonists
Brite
Anatomical Therapeutic Chemical (ATC) classification [BR:br08303]
 R RESPIRATORY SYSTEM
  R06 ANTIHISTAMINES FOR SYSTEMIC USE
   R06A ANTIHISTAMINES FOR SYSTEMIC USE
    R06AB Substituted alkylamines
     R06AB01 Brompheniramine
      D00663  Brompheniramine maleate (USAN)
Target-based classification of drugs [BR:br08310]
 G Protein-coupled receptors
  Rhodopsin family
   Histamine
    HRH1
     D00663  Brompheniramine maleate (USAN)
Rx-to-OTC switch list in the USA [br08315.html]
 D00663
BRITE hierarchy
Other DBs
CAS: 980-71-2
PubChem: 7847729
ChEBI: 3184
ChEMBL: CHEMBL1200961
DrugBank: DB00835
LigandBox: D00663
NIKKAJI: J300.656E
LinkDB All DBs
KCF data Show

ATOM        27
            1   C1c C    18.0996  -18.1067
            2   C8y C    16.8914  -18.8188
            3   C8y C    19.3078  -18.7954
            4   C1b C    18.1053  -16.7002
            5   C8x C    15.6716  -18.1241
            6   C8x C    16.9031  -20.2136
            7   C8x C    19.3078  -20.2020
            8   N5x N    20.5158  -18.0891
            9   C1b C    19.3078  -16.0115
            10  C8x C    14.4692  -18.8362
            11  C8x C    15.6949  -20.9200
            12  C8x C    20.5158  -20.8966
            13  C8x C    21.7356  -18.7954
            14  N1c N    19.3018  -14.6107
            15  C8y C    14.4808  -20.2370
            16  C8x C    21.7356  -20.2020
            17  C1a C    18.0879  -13.9044
            18  C1a C    20.5158  -13.8927
            19  X   Br   13.2669  -20.9433
            20  C2b C    27.0527  -16.2332
            21  C2b C    25.4185  -16.2389
            22  C6a C    27.7297  -17.4063
            23  C6a C    24.7415  -17.4180
            24  O6a O    27.0586  -18.5795
            25  O6a O    29.0955  -17.3946
            26  O6a O    23.3815  -17.4180
            27  O6a O    25.4302  -18.5911
BOND        27
            1     1   2 1
            2     1   3 1
            3     1   4 1
            4     2   5 1
            5     2   6 2
            6     3   7 1
            7     3   8 2
            8     4   9 1
            9     5  10 2
            10    6  11 1
            11    7  12 2
            12    8  13 1
            13    9  14 1
            14   10  15 1
            15   12  16 1
            16   14  17 1
            17   14  18 1
            18   15  19 1
            19   11  15 2
            20   13  16 2
            21   20  21 2
            22   20  22 1
            23   21  23 1
            24   22  24 1
            25   22  25 2
            26   23  26 1
            27   23  27 2

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