KEGG   DRUG: Levetiracetam
Entry
D00709                      Drug                                   

Name
Levetiracetam (JAN/USP/INN);
Keppra (TN);
E keppra (TN)
Product
  Generic
LEVERTIRACETAM (Direct_Rx), LEVETIRACETAM (A-S Medication Solutions), LEVETIRACETAM (A-S Medication Solutions), LEVETIRACETAM (A-S Medication Solutions), LEVETIRACETAM (A-S Medication Solutions), LEVETIRACETAM (ACETRIS HEALTH), LEVETIRACETAM (ACI Healthcare USA), LEVETIRACETAM (Accord Healthcare), LEVETIRACETAM (Actavis Pharma), LEVETIRACETAM (Alembic Pharmaceuticals), LEVETIRACETAM (American Health Packaging), LEVETIRACETAM (American Health Packaging), LEVETIRACETAM (Amneal Pharmaceuticals LLC), LEVETIRACETAM (Amneal Pharmaceuticals LLC), LEVETIRACETAM (Apotex Corp.), LEVETIRACETAM (Athenex Pharmaceutical Division), LEVETIRACETAM (Atlantic Biologicals Corps), LEVETIRACETAM (Atlantic Biologicals Corps.), LEVETIRACETAM (AuroMedics Pharma LLC), LEVETIRACETAM (AuroMedics Pharma LLC), LEVETIRACETAM (Aurobindo Pharma Limited), LEVETIRACETAM (Aurobindo Pharma Limited), LEVETIRACETAM (AvKARE), LEVETIRACETAM (AvPAK), LEVETIRACETAM (AvPAK), LEVETIRACETAM (BluePoint Laboratories), LEVETIRACETAM (BluePoint Laboratories), LEVETIRACETAM (BluePoint Laboratories), LEVETIRACETAM (Breckenridge Pharmaceutical), LEVETIRACETAM (Bryant Ranch Prepack), LEVETIRACETAM (Bryant Ranch Prepack), LEVETIRACETAM (Bryant Ranch Prepack), LEVETIRACETAM (Bryant Ranch Prepack), LEVETIRACETAM (Bryant Ranch Prepack), LEVETIRACETAM (Bryant Ranch Prepack), LEVETIRACETAM (Cadila Healthcare Limited), LEVETIRACETAM (Camber Pharmaceuticals), LEVETIRACETAM (Camber Pharmaceuticals), LEVETIRACETAM (Cardinal Health), LEVETIRACETAM (Cardinal Health), LEVETIRACETAM (Cardinal Health), LEVETIRACETAM (Changzhou Pharmaceutical Factory), LEVETIRACETAM (China Resources Saike Pharmaceutical), LEVETIRACETAM (Clinical Solutions Wholesale), LEVETIRACETAM (DIRECT RX), LEVETIRACETAM (DIRECT RX), LEVETIRACETAM (DIRECT RX), LEVETIRACETAM (Denton Pharma), LEVETIRACETAM (Direct_Rx), LEVETIRACETAM (Direct_Rx), LEVETIRACETAM (Dr. Reddy's Laboratories Limited), LEVETIRACETAM (Dr. Reddy's Laboratories Limited), LEVETIRACETAM (Exelan Pharmaceuticals), LEVETIRACETAM (Eywa Pharma), LEVETIRACETAM (Fresenius Kabi USA), LEVETIRACETAM (Fresenius Kabi USA), LEVETIRACETAM (Gland Pharma Limited), LEVETIRACETAM (Golden State Medical Supply), LEVETIRACETAM (Hi-Tech Pharmacal), LEVETIRACETAM (Hospira), LEVETIRACETAM (Hospira), LEVETIRACETAM (IntelliPharmaCeutics Corp.), LEVETIRACETAM (Lannett Company), LEVETIRACETAM (Lohxa), LEVETIRACETAM (Lupin Pharmaceuticals), LEVETIRACETAM (Lupin Pharmaceuticals), LEVETIRACETAM (Lupin Pharmaceuticals), LEVETIRACETAM (Major Pharmaceuticals), LEVETIRACETAM (Marlex Pharmaceuticals), LEVETIRACETAM (McKesson Corporation dba SKY Packaging), LEVETIRACETAM (Mckesson Corporation DBA SKY Packaginng), LEVETIRACETAM (Micro Labs Limited), LEVETIRACETAM (Morton Grove Pharmaceuticals), LEVETIRACETAM (Mylan Institutional), LEVETIRACETAM (Mylan Institutional LLC), LEVETIRACETAM (Mylan Pharmaceuticals), LEVETIRACETAM (NCS HealthCare of KY), LEVETIRACETAM (NCS HealthCare of KY), LEVETIRACETAM (NCS HealthCare of KY), LEVETIRACETAM IN SODIUM CHLORIDE (Nexus Pharmaceuticals), LEVETIRACETAM (NorthStar Rx LLC), LEVETIRACETAM (NorthStar Rx LLC), ROWEEPRA (OWP Pharmaceuticals), ROWEEPRA (OWP Pharmaceuticals), ROWEEPRA XR (OWP Pharmaceuticals), LEVETIRACETAM (PD-Rx Pharmaceuticals), LEVETIRACETAM (PD-Rx Pharmaceuticals), LEVETIRACETAM (Par Pharmaceutical), LEVETIRACETAM (Par Pharmaceutical), LEVETIRACETAM (PharmTak), LEVETIRACETAM (Pharmaceutical Associates), LEVETIRACETAM (Preferred Pharmaceuticals), LEVETIRACETAM (Preferred Pharmaceuticals), LEVETIRACETAM (Preferred Pharmaceuticals), LEVETIRACETAM (Preferred Pharmaceuticals), LEVETIRACETAM (Preferred Pharmaceuticals), LEVETIRACETAM (Prinston Pharmaceutical), LEVETIRACETAM (Proficient Rx LP), LEVETIRACETAM (Quinn Pharmaceuticals), LEVETIRACETAM (REMEDYREPACK), LEVETIRACETAM (REMEDYREPACK), LEVETIRACETAM (REMEDYREPACK), LEVETIRACETAM (REMEDYREPACK), LEVETIRACETAM (REMEDYREPACK), LEVETIRACETAM (REMEDYREPACK), LEVETIRACETAM (REMEDYREPACK), LEVETIRACETAM (REMEDYREPACK), LEVETIRACETAM (REMEDYREPACK), LEVETIRACETAM (REMEDYREPACK), LEVETIRACETAM (REMEDYREPACK), LEVETIRACETAM (REMEDYREPACK), LEVETIRACETAM (RedPharm Drug), LEVETIRACETAM (RedPharm Drug), LEVETIRACETAM (Rising Pharmaceuticals), LEVETIRACETAM (Sagent Pharmaceuticals), LEVETIRACETAM (Solco Healthcare US), LEVETIRACETAM (Solco Healthcare US), LEVETIRACETAM (Sun Pharmaceutical Industries), LEVETIRACETAM (TAGI Pharma), LEVETIRACETAM (Taro Pharmaceuticals U.S.A.), LEVETIRACETAM (Torrent Pharmaceuticals Limited), LEVETIRACETAM (Trupharma), LEVETIRACETAM (VistaPharm), LEVETIRACETAM (West-Ward Pharmaceuticals Corp), LEVETIRACETAM (West-Ward Pharmaceuticals Corp), LEVETIRACETAM (X-GEN Pharmaceuticals), LEVETIRACETAM (Zydus Pharmaceuticals (USA)), LEVETIRACETAM (Dr.Reddy's Laboratories), LEVETIRACETAM (Dr.Reddy's Laboratories), LEVETIRACETAM (Jubilant Cadista Pharmaceuticals), LEVETIRACTAM (Akorn)
Formula
C8H14N2O2
Exact mass
170.1055
Mol weight
170.209
Structure
Simcomp
Class
Neuropsychiatric agent
 DG02038  Piracetam antiepileptics
Remark
Same as: C07841
Therapeutic category: 1139
ATC code: N03AX14
Product: D00709<JP/US>
Efficacy
Antiepileptic
  Disease
Juvenile myoclonic epilepsy [DS:H00808]
Comment
Piracetam derivative
Target
SV2A [HSA:9900] [KO:K06258]
  Pathway
hsa04512  ECM-receptor interaction
Interaction
Structure map
map07033  Anticonvulsants
Brite
Anatomical Therapeutic Chemical (ATC) classification [BR:br08303]
 N NERVOUS SYSTEM
  N03 ANTIEPILEPTICS
   N03A ANTIEPILEPTICS
    N03AX Other antiepileptics
     N03AX14 Levetiracetam
      D00709  Levetiracetam (JAN/USP/INN) <JP/US>
USP drug classification [BR:br08302]
 Anticonvulsants
  Anticonvulsants, Other
   Potassium Channel Opener
    Levetiracetam
     D00709  Levetiracetam (JAN/USP/INN)
Therapeutic category of drugs in Japan [BR:br08301]
 1  Agents affecting nervous system and sensory organs
  11  Agents affecting central nervous system
   113  Antiepileptics
    1139  Others
     D00709  Levetiracetam (JAN/USP/INN)
Target-based classification of drugs [BR:br08310]
 Transporters
  Major facilitator superfamily
   VNT family
    SV2A
     D00709  Levetiracetam (JAN/USP/INN) <JP/US>
New drug approvals in the USA [br08319.html]
 New molecular entities and new therapeutic biological products
  D00709
New drug approvals in Europe [br08329.html]
 European public assessment reports (EPAR) authorised medicine
  D00709
New drug approvals in Japan [br08318.html]
 Drugs with new active ingredients
  D00709
New drug approvals in the USA, Europe and Japan [br08328.html]
 Approval dates by FDA, EMA and PMDA
  D00709
Other DBs
CAS: 102767-28-2
PubChem: 7847774
ChEBI: 6437
ChEMBL: CHEMBL1286
DrugBank: DB01202
LigandBox: D00709
NIKKAJI: J523.599E
LinkDB
KCF data

ATOM        12
            1   N1y N    17.9529  -16.5972
            2   C1c C    19.1587  -15.8890
            3   C5x C    16.8171  -15.7718
            4   C1x C    17.5138  -17.9261
            5   C5a C    20.3647  -16.5855
            6   C1x C    15.6816  -16.5972
            7   O5x O    16.7996  -14.3728
            8   C1x C    16.1146  -17.9261
            9   N1a N    21.5766  -15.8832
            10  O5a O    20.3588  -17.9847
            11  C1b C    19.1536  -14.4902
            12  C1a C    20.3832  -13.7742
BOND        12
            1     1   2 1
            2     1   3 1
            3     1   4 1
            4     2   5 1
            5     3   6 1
            6     3   7 2
            7     4   8 1
            8     5   9 1
            9     5  10 2
            10    6   8 1
            11    2  11 1 #Up
            12   11  12 1

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