KEGG   DRUG: Levetiracetam
Entry
D00709                      Drug                                   
Name
Levetiracetam (JAN/USP/INN);
Keppra (TN);
E keppra (TN)
Product
KEPPRA (UCB), KEPPRA (UCB), KEPPRA (UCB), LEVETIRACETAM (Mylan Institutional LLC), LEVETIRACETAM (TRIPOINT THERAPEUTICS), LEVETIRACETAM (WG Critical Care), LEVETIRACETAM (WG Critical Care), SPRITAM (Aprecia Pharmaceuticals)
  Generic
LEVETIRACETAM (A-S Medication Solutions), LEVETIRACETAM (A-S Medication Solutions), LEVETIRACETAM (A-S Medication Solutions), LEVETIRACETAM (A-S Medication Solutions), LEVETIRACETAM (A-S Medication Solutions), LEVETIRACETAM (ACI Healthcare USA), LEVETIRACETAM (APNAR PHARMA LP), LEVETIRACETAM (ATLANTIC BIOLOGICALS CORP.), LEVETIRACETAM (Actavis Pharma), LEVETIRACETAM (American Health Packaging), LEVETIRACETAM (American Health Packaging), LEVETIRACETAM (American Health Packaging), LEVETIRACETAM (Amneal Pharmaceuticals LLC), LEVETIRACETAM (Amneal Pharmaceuticals LLC), LEVETIRACETAM (Apotex Corp.), LEVETIRACETAM (Armas Pharmaceuticals), LEVETIRACETAM (Ascend Laboratories), LEVETIRACETAM (Aurobindo Pharma Limited), LEVETIRACETAM (Aurobindo Pharma Limited), LEVETIRACETAM (AvPAK), LEVETIRACETAM (B. Braun Medical), LEVETIRACETAM (Baxter Healthcare Corporation), LEVETIRACETAM (Bionpharma), LEVETIRACETAM (BluePoint Laboratories), LEVETIRACETAM (BluePoint Laboratories), LEVETIRACETAM (Bryant Ranch Prepack), LEVETIRACETAM (Bryant Ranch Prepack), LEVETIRACETAM (Bryant Ranch Prepack), LEVETIRACETAM (Bryant Ranch Prepack), LEVETIRACETAM (Bryant Ranch Prepack), LEVETIRACETAM (Bryant Ranch Prepack), LEVETIRACETAM (Bryant Ranch Prepack), LEVETIRACETAM (Bryant Ranch Prepack), LEVETIRACETAM (Bryant Ranch Prepack), LEVETIRACETAM (Bryant Ranch Prepack), LEVETIRACETAM (Bryant Ranch Prepack), LEVETIRACETAM (Bryant Ranch Prepack), LEVETIRACETAM (Camber Pharmaceuticals), LEVETIRACETAM (Camber Pharmaceuticals), LEVETIRACETAM (Caplin Steriles Limited), LEVETIRACETAM (Cardinal Health 107), LEVETIRACETAM (Cardinal Health 107), LEVETIRACETAM (Cardinal Health 107), LEVETIRACETAM (Cardinal Health 107), LEVETIRACETAM (Civica), LEVETIRACETAM (Coupler LLC), LEVETIRACETAM (Coupler LLC), LEVETIRACETAM (DIRECT RX), LEVETIRACETAM (Dr. Reddy's Laboratories Limited), LEVETIRACETAM (Dr. Reddy's Laboratories Limited), LEVETIRACETAM (Dr.Reddy's Laboratories), LEVETIRACETAM (Dr.Reddy's Laboratories), LEVETIRACETAM (Eugia US LLC), LEVETIRACETAM (Eugia US LLC), LEVETIRACETAM (Exelan Pharmaceuticals), LEVETIRACETAM (Fresenius Kabi USA), LEVETIRACETAM (Fresenius Kabi USA), LEVETIRACETAM (Gland Pharma Limited), LEVETIRACETAM (Golden State Medical Supply), LEVETIRACETAM (Granules Pharmaceuticals), LEVETIRACETAM (Hikma Pharmaceuticals USA), LEVETIRACETAM (Hikma Pharmaceuticals USA), LEVETIRACETAM (Hisun Pharmaceuticals USA), LEVETIRACETAM (Hospira), LEVETIRACETAM (Hospira), LEVETIRACETAM (IntelliPharmaCeutics Corp.), LEVETIRACETAM (Laurus Generics), LEVETIRACETAM (Lupin Pharmaceuticals), LEVETIRACETAM (Lupin Pharmaceuticals), LEVETIRACETAM (MAJOR PHARMACEUTICALS), LEVETIRACETAM (Major Pharmaceuticals), LEVETIRACETAM (Major Pharmaceuticals), LEVETIRACETAM (McKesson Corporation dba SKY Packaging), LEVETIRACETAM (Mckesson Corporation DBA SKY Packaginng), LEVETIRACETAM (Micro Labs Limited), LEVETIRACETAM (Mylan Institutional LLC), LEVETIRACETAM (Mylan Institutional), LEVETIRACETAM (Mylan Pharmaceuticals), LEVETIRACETAM (NCS HealthCare of KY), LEVETIRACETAM (Natco Pharma USA LLC), LEVETIRACETAM (NorthStar Rx LLC), LEVETIRACETAM (NorthStar Rx LLC), LEVETIRACETAM (NorthStar RxLLC), LEVETIRACETAM (Northwind Pharmaceuticals), LEVETIRACETAM (Novadoz Pharmaceuticals LLC), LEVETIRACETAM (Novadoz Pharmaceuticals LLC), LEVETIRACETAM (Novadoz Pharmaceuticals LLC), LEVETIRACETAM (OWP Pharmaceuticals), LEVETIRACETAM (Omnivium Pharmaceuticals LLC), LEVETIRACETAM (PAI Holdings), LEVETIRACETAM (PD-Rx Pharmaceuticals), LEVETIRACETAM (PD-Rx Pharmaceuticals), LEVETIRACETAM (PD-Rx Pharmaceuticals), LEVETIRACETAM (Patrin Pharma), LEVETIRACETAM (Prasco Laboratories), LEVETIRACETAM (Precision Dose), LEVETIRACETAM (Preferred Pharmaceuticals), LEVETIRACETAM (Preferred Pharmaceuticals), LEVETIRACETAM (Preferred Pharmaceuticals), LEVETIRACETAM (Preferred Pharmaceuticals), LEVETIRACETAM (Prinston Pharmaceutical), LEVETIRACETAM (Proficient Rx LP), LEVETIRACETAM (Proficient Rx LP), LEVETIRACETAM (Proficient Rx LP), LEVETIRACETAM (Quallent Pharmaceuticals Health LLC), LEVETIRACETAM (REMEDYREPACK), LEVETIRACETAM (REMEDYREPACK), LEVETIRACETAM (REMEDYREPACK), LEVETIRACETAM (REMEDYREPACK), LEVETIRACETAM (REMEDYREPACK), LEVETIRACETAM (REMEDYREPACK), LEVETIRACETAM (REMEDYREPACK), LEVETIRACETAM (REMEDYREPACK), LEVETIRACETAM (REMEDYREPACK), LEVETIRACETAM (REMEDYREPACK), LEVETIRACETAM (REMEDYREPACK), LEVETIRACETAM (REMEDYREPACK), LEVETIRACETAM (REMEDYREPACK), LEVETIRACETAM (REMEDYREPACK), LEVETIRACETAM (REMEDYREPACK), LEVETIRACETAM (REMEDYREPACK), LEVETIRACETAM (REMEDYREPACK), LEVETIRACETAM (REMEDYREPACK), LEVETIRACETAM (Redpharm Drug), LEVETIRACETAM (Rising Pharma Holdings), LEVETIRACETAM (Rising Pharma Holdings), LEVETIRACETAM (SOHM), LEVETIRACETAM (Sagent Pharmaceuticals), LEVETIRACETAM (Sagent Pharmaceuticals), LEVETIRACETAM (ScieGen Pharmaceuticals), LEVETIRACETAM (ScieGen Pharmaceuticals), LEVETIRACETAM (Solco Healthcare US), LEVETIRACETAM (Solco Healthcare US), LEVETIRACETAM (Solco healthcare U.S.), LEVETIRACETAM (TAGI Pharma), LEVETIRACETAM (Taro Pharmaceuticals U.S.A.), LEVETIRACETAM (Torrent Pharmaceuticals Limited), LEVETIRACETAM (Tris Pharma), LEVETIRACETAM (Westminster Pharmaceuticals), LEVETIRACETAM (XLCare Pharmaceuticals), LEVETIRACETAM (Zydus Lifesciences Limited), LEVETIRACETAM (Zydus Pharmaceuticals USA), LEVETIRACETAM ER (Direct_Rx), LEVETIRACETAM IN SODIUM CHLORIDE (Nexus Pharmaceuticals LLC), LEVETIRACETAM SOLUTION (Chartwell RX)
Formula
C8H14N2O2
Exact mass
170.1055
Mol weight
170.21
Structure
Simcomp
Class
Neuropsychiatric agent
 DG03199  Antiepileptic agent
  DG02038  Piracetam antiepileptic
Remark
Same as: C07841
Therapeutic category: 1139
ATC code: N03AX14
Product: D00709<JP/US>
Efficacy
Antiepileptic
  Disease
Juvenile myoclonic epilepsy [DS:H00808]
Comment
Piracetam derivative
Target
SV2A [HSA:9900] [KO:K06258]
  Pathway
hsa04512  ECM-receptor interaction
Interaction
Structure map
map07033  Anticonvulsants
Brite
Anatomical Therapeutic Chemical (ATC) classification [BR:br08303]
 N NERVOUS SYSTEM
  N03 ANTIEPILEPTICS
   N03A ANTIEPILEPTICS
    N03AX Other antiepileptics
     N03AX14 Levetiracetam
      D00709  Levetiracetam (JAN/USP/INN) <JP/US>
USP drug classification [BR:br08302]
 Anticonvulsants
  Anticonvulsants, Other
   Levetiracetam
    D00709  Levetiracetam (JAN/USP/INN)
Therapeutic category of drugs in Japan [BR:br08301]
 1  Agents affecting nervous system and sensory organs
  11  Agents affecting central nervous system
   113  Antiepileptics
    1139  Others
     D00709  Levetiracetam (JAN/USP/INN)
Drug groups [BR:br08330]
 Neuropsychiatric agent
  DG03199  Antiepileptic agent
   DG02038  Piracetam antiepileptic
    D00709  Levetiracetam
Drug classes [BR:br08332]
 Neuropsychiatric agent
  DG03199  Antiepileptic agent
   D00709  Levetiracetam
Target-based classification of drugs [BR:br08310]
 Transporters
  Major facilitator superfamily
   VNT family
    SV2A
     D00709  Levetiracetam (JAN/USP/INN) <JP/US>
New drug approvals in the USA [br08319.html]
 New molecular entities and new therapeutic biological products
  D00709
New drug approvals in Europe [br08329.html]
 European public assessment reports (EPAR) authorised medicine
  D00709
New drug approvals in Japan [br08318.html]
 Drugs with new active ingredients
  D00709
New drug approvals in the USA, Europe and Japan [br08328.html]
 Approval dates by FDA, EMA and PMDA
  D00709
Other DBs
CAS: 102767-28-2
PubChem: 7847774
ChEBI: 6437
PDB-CCD: UKX[PDBj]
LigandBox: D00709
NIKKAJI: J523.599E
LinkDB
KCF data

ATOM        12
            1   N1y N    17.9529  -16.5972
            2   C1c C    19.1587  -15.8890
            3   C5x C    16.8171  -15.7718
            4   C1x C    17.5138  -17.9261
            5   C5a C    20.3647  -16.5855
            6   C1x C    15.6816  -16.5972
            7   O5x O    16.7996  -14.3728
            8   C1x C    16.1146  -17.9261
            9   N1a N    21.5766  -15.8832
            10  O5a O    20.3588  -17.9847
            11  C1b C    19.1536  -14.4902
            12  C1a C    20.3832  -13.7742
BOND        12
            1     1   2 1
            2     1   3 1
            3     1   4 1
            4     2   5 1
            5     3   6 1
            6     3   7 2
            7     4   8 1
            8     5   9 1
            9     5  10 2
            10    6   8 1
            11    2  11 1 #Up
            12   11  12 1

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