Entry |
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Name |
Cefazolin sodium (JP18/USP); Ancef (TN) |
Product |
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Generic |
CEFAZOLIN (A-S Medication Solutions), CEFAZOLIN (Apotex Corp.), CEFAZOLIN (Apotex Corp.), CEFAZOLIN (Apotex Corp.), CEFAZOLIN (Apotex Corp.), CEFAZOLIN (Civica), CEFAZOLIN (Civica), CEFAZOLIN (Fresenius Kabi USA), CEFAZOLIN (Fresenius Kabi USA), CEFAZOLIN (General Injectables & Vaccines), CEFAZOLIN (General Injectables and Vaccines), CEFAZOLIN (Henry Schein), CEFAZOLIN (Henry Schein), CEFAZOLIN (Henry Schein), CEFAZOLIN (Hikma Pharmaceuticals USA), CEFAZOLIN (Hikma Pharmaceuticals USA), CEFAZOLIN (Hikma Pharmaceuticals USA), CEFAZOLIN (Hikma Pharmaceuticals USA), CEFAZOLIN (Hospira), CEFAZOLIN (Medical Purchasing Solutions), CEFAZOLIN (Medical Purchasing Solutions), CEFAZOLIN (Proficient Rx LP), CEFAZOLIN (Qilu Pharmaceutical), CEFAZOLIN (REMEDYREPACK), CEFAZOLIN (Sagent Pharmaceuticals), CEFAZOLIN (Sagent Pharmaceuticals), CEFAZOLIN (Samson Medical Technologies), CEFAZOLIN (Sandoz), CEFAZOLIN (Sandoz), CEFAZOLIN (WG Critical Care), CEFAZOLIN (WG Critical Care), CEFAZOLIN (WG Critical Care) |
Formula |
C14H13N8O4S3. Na
|
Exact mass |
476.0120
|
Mol weight |
476.50
|
Structure |
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Simcomp |
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Class |
|
Remark |
Therapeutic category: | 6132 |
Product (DG00550): | D00905<JP/US> D02226<JP> |
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Efficacy |
Antibacterial, Cell wall biosynthesis inhibitor |
Disease |
Bacterial endocarditis [DS: H00334] |
Target |
penicillin binding protein |
Pathway |
|
Interaction |
|
Structure map |
map07012 | Cephalosporins - parenteral agents |
|
Brite |
Anatomical Therapeutic Chemical (ATC) classification [BR:br08303]
J ANTIINFECTIVES FOR SYSTEMIC USE
J01 ANTIBACTERIALS FOR SYSTEMIC USE
J01D OTHER BETA-LACTAM ANTIBACTERIALS
J01DB First-generation cephalosporins
J01DB04 Cefazolin
D00905 Cefazolin sodium (JP18/USP) <JP/US>
USP drug classification [BR:br08302]
Antibacterials
Beta-lactam, Cephalosporins
Cefazolin
D00905 Cefazolin sodium (JP18/USP)
Therapeutic category of drugs in Japan [BR:br08301]
6 Agents against pathologic organisms and parasites
61 Antibiotics
613 Acting mainly on gram-positive and gram-negative bacteria
6132 Cephem antibioitics
D00905 Cefazolin sodium (JP18/USP)
Drug groups [BR:br08330]
Antibacterial
DG01710 beta-Lactam antibiotic
DG01714 Cephalosporin skeleton group
DG01488 Cephem
DG00550 Cefazolin
D00905 Cefazolin sodium
DG01774 First-generation cephalosporin
DG00550 Cefazolin
D00905 Cefazolin sodium
Drug classes [BR:br08332]
Antibacterial
DG01488 Cephem
D00905 Cefazolin sodium
Antimicrobials [BR:br08307]
Antibacterials
Cell wall biosynthesis inhibitor, beta-lactam
First-generation cephalosporin
D00905 Cefazolin sodium (JP18/USP) <JP/US>
Drugs listed in the Japanese Pharmacopoeia [BR:br08311]
Chemicals
D00905 Cefazolin sodium
D00905 Cefazolin sodium for injection
Drug groups [BR:br08330]
Antibacterial
DG01710 beta-Lactam antibiotic
DG01714 Cephalosporin skeleton group
DG01488 Cephem
DG00550 Cefazolin
DG01774 First-generation cephalosporin
DG00550 Cefazolin
Antimicrobials abbreviations [BR:br08327]
Antibacterials
Cell wall biosynthesis inhibitor, beta-lactam
First-generation cephalosporin
DG00550 Cefazolin
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Other DBs |
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LinkDB |
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KCF data |
ATOM 30
1 C1y C 18.0487 -14.7849
2 N1y N 18.0487 -16.1806
3 C2y C 19.2576 -16.8783
4 C2y C 20.4663 -16.1806
5 C1x C 20.4663 -14.7849
6 S2x S 19.2576 -14.0870
7 C1y C 16.6529 -14.7849
8 C5x C 16.6529 -16.1806
9 N1b N 15.4443 -14.0870
10 C5a C 14.2354 -14.7849
11 O5a O 14.2354 -16.1806
12 O5x O 15.4443 -16.8783
13 C1b C 13.0266 -14.0870
14 C1b C 21.6935 -16.8895
15 C6a C 19.2576 -18.2739
16 O6a O 18.0319 -18.9816
17 O6a O 20.4493 -18.9621 #-
18 N4y N 11.7985 -14.7965
19 S2a S 22.9071 -16.1890
20 C8y C 24.1155 -16.8870
21 N5x N 24.5393 -18.2151
22 N5x N 25.9360 -18.2265
23 C8y C 26.3784 -16.9017
24 S2x S 25.2552 -16.0715
25 C1a C 27.7744 -16.8829
26 C8x C 10.6469 -13.9856
27 N5x N 9.5153 -14.8305
28 N5x N 9.9690 -16.1679
29 N5x N 11.3811 -16.1498
30 Z Na 21.9094 -18.8997 #+
BOND 32
1 1 2 1
2 2 3 1
3 3 4 2
4 4 5 1
5 5 6 1
6 1 6 1
7 1 7 1
8 7 8 1
9 2 8 1
10 7 9 1 #Up
11 9 10 1
12 10 11 2
13 8 12 2
14 10 13 1
15 4 14 1
16 3 15 1
17 15 16 2
18 15 17 1
19 13 18 1
20 14 19 1
21 19 20 1
22 20 21 2
23 21 22 1
24 22 23 2
25 23 24 1
26 20 24 1
27 23 25 1
28 18 26 1
29 26 27 2
30 27 28 1
31 28 29 2
32 18 29 1
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