Entry |
|
Name |
Ceftazidime (USP); Ceftazidime hydrate (JP18); Ceftazidime pentahydrate; Fortaz (TN); Tazicef (TN) |
Product |
|
Generic |
|
Formula |
C22H22N6O7S2. 5H2O
|
Exact mass |
636.1520
|
Mol weight |
636.66
|
Structure |
|
Simcomp |
|
Class |
|
Remark |
Therapeutic category: | 6132 |
Product (DG00571): | D00921<JP/US> |
Product (mixture): | D10779<JP/US> |
|
Efficacy |
Antibacterial, Cell wall biosynthesis inhibitor |
Target |
penicillin binding protein |
Pathway |
|
Interaction |
|
Structure map |
map07012 | Cephalosporins - parenteral agents |
|
Brite |
Anatomical Therapeutic Chemical (ATC) classification [BR:br08303]
J ANTIINFECTIVES FOR SYSTEMIC USE
J01 ANTIBACTERIALS FOR SYSTEMIC USE
J01D OTHER BETA-LACTAM ANTIBACTERIALS
J01DD Third-generation cephalosporins
J01DD02 Ceftazidime
D00921 Ceftazidime (USP) <JP/US>
USP drug classification [BR:br08302]
Antibacterials
Beta-lactam, Cephalosporins
Ceftazidime
D00921 Ceftazidime (USP)
Therapeutic category of drugs in Japan [BR:br08301]
6 Agents against pathologic organisms and parasites
61 Antibiotics
613 Acting mainly on gram-positive and gram-negative bacteria
6132 Cephem antibioitics
D00921 Ceftazidime (USP); Ceftazidime hydrate (JP18)
Drug groups [BR:br08330]
Antibacterial
DG01710 beta-Lactam antibiotic
DG01714 Cephalosporin skeleton group
DG01488 Cephem
DG00571 Ceftazidime
D00921 Ceftazidime
DG01776 Third-generation cephalosporin
DG00571 Ceftazidime
D00921 Ceftazidime
DG01804 Oxyimino beta-lactam
DG00571 Ceftazidime
D00921 Ceftazidime
Drug classes [BR:br08332]
Antibacterial
DG01488 Cephem
D00921 Ceftazidime
Antimicrobials [BR:br08307]
Antibacterials
Cell wall biosynthesis inhibitor, beta-lactam
Third-generation cephalosporin
D00921 Ceftazidime (USP) <JP/US>
Drugs listed in the Japanese Pharmacopoeia [BR:br08311]
Chemicals
D00921 Ceftazidime hydrate
D00921 Ceftazidime for injection
Drug groups [BR:br08330]
Antibacterial
DG01710 beta-Lactam antibiotic
DG01714 Cephalosporin skeleton group
DG01488 Cephem
DG00571 Ceftazidime
DG01776 Third-generation cephalosporin
DG00571 Ceftazidime
DG01804 Oxyimino beta-lactam
DG00571 Ceftazidime
Antimicrobials abbreviations [BR:br08327]
Antibacterials
Cell wall biosynthesis inhibitor, beta-lactam
Third-generation cephalosporin
DG00571 Ceftazidime
|
Other DBs |
|
LinkDB |
|
KCF data |
ATOM 42
1 C1y C 32.7600 -19.2500
2 N1y N 32.7600 -20.6500
3 C2y C 33.9500 -21.3500
4 C2y C 35.1400 -20.6500
5 C1x C 35.1400 -19.2500
6 S2x S 33.9500 -18.5500
7 C1y C 31.3600 -19.2500
8 C5x C 31.3600 -20.6500
9 N1b N 30.1000 -18.5500
10 C5a C 28.9100 -19.2500
11 O5a O 28.9100 -20.6500
12 O5x O 30.1000 -21.3500
13 C2c C 27.7200 -18.5500
14 C1b C 36.4000 -21.3500
15 C8y C 26.4600 -19.2500
16 C8x C 25.4100 -18.4100
17 S2x S 24.2200 -19.1800
18 C8y C 24.6400 -20.5800
19 N5x N 26.0400 -20.5800
20 N2b N 27.7200 -17.1500
21 C6a C 33.9500 -22.7500
22 O6a O 35.1400 -23.4500 #-
23 O6a O 32.6900 -23.4500
24 N1a N 23.8000 -21.7000
25 N5y N 37.5900 -20.5800 #+
26 C8x C 38.7800 -21.2800
27 C8x C 39.9700 -20.5800
28 C8x C 39.9700 -19.1800
29 C8x C 38.7800 -18.4800
30 C8x C 37.5900 -19.1800
31 O2a O 28.9100 -16.4500
32 C1d C 28.9100 -15.0500
33 C1a C 28.9100 -13.6500
34 C6a C 30.3100 -15.0500
35 C1a C 27.5100 -15.0500
36 O6a O 31.0100 -16.2400
37 O6a O 31.0100 -13.8600
38 O0 O 27.7200 -22.8200
39 O0 O 27.7200 -22.8200
40 O0 O 27.7200 -22.8200
41 O0 O 27.7200 -22.8200
42 O0 O 27.7200 -22.8200
BOND 40
1 1 2 1
2 2 3 1
3 3 4 2
4 4 5 1
5 5 6 1
6 1 6 1
7 1 7 1
8 7 8 1
9 2 8 1
10 7 9 1 #Up
11 9 10 1
12 10 11 2
13 8 12 2
14 10 13 1
15 4 14 1
16 13 15 1
17 15 16 2
18 16 17 1
19 17 18 1
20 18 19 2
21 15 19 1
22 13 20 2
23 3 21 1
24 21 22 1
25 21 23 2
26 18 24 1
27 14 25 1
28 25 26 2
29 26 27 1
30 27 28 2
31 28 29 1
32 29 30 2
33 25 30 1
34 20 31 1
35 31 32 1
36 32 33 1
37 32 34 1
38 32 35 1
39 34 36 1
40 34 37 2
BRACKET 1 25.6200 -23.4500 25.6200 -22.0500
1 28.2100 -22.0500 28.2100 -23.4500
1 5
ORIGINAL 1 39
REPEAT 1 40 41 42 43
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