| Entry |
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| Name |
Nafcillin sodium (USP);
Nafcillin sodium monohydrate;
Unipen (TN) |
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| Product |
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| Generic |
NAFCILLIN (Athenex Pharmaceutical Division), NAFCILLIN (Athenex Pharmaceutical Division), NAFCILLIN (Avenacy), NAFCILLIN (Eugia US LLC), NAFCILLIN (Eugia US LLC), NAFCILLIN (Eugia US LLC), NAFCILLIN (Eugia US LLC), NAFCILLIN (Fresenius Kabi USA), NAFCILLIN (Fresenius Kabi USA), NAFCILLIN (Fresenius Kabi USA), NAFCILLIN (Heritage Pharmaceuticals Inc. d/b/a/ Avet Pharmaceuticals), NAFCILLIN (Methapharm), NAFCILLIN (NorthStar Rx), NAFCILLIN (NorthStar Rx), NAFCILLIN (Sagent Pharmaceuticals), NAFCILLIN (Sagent Pharmaceuticals), NAFCILLIN (WG Critical Care), NAFCILLIN (WG Critical Care), NAFCILLIN SODIUM (Armas Pharmaceuticals), NAFCILLIN SODIUM (Steriscience Specialties Private Limited) |
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| Formula |
C21H21N2O5S. Na. H2O
|
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| Exact mass |
454.1175
|
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| Mol weight |
454.47
|
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| Structure |
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| Simcomp |
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| Class |
Antibacterial
DG01710 beta-Lactam antibiotic
DG01713 Penicillin skeleton group
DG01480 Penicillin
DG01779 beta-Lactamase resistant penicillin
|
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| Remark |
| Product (DG00544): | D00928<US> |
|
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| Efficacy |
Antibacterial, Cell wall biosynthesis inhibitor |
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| Target |
penicillin binding protein |
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| Pathway |
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| Interaction |
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| Brite |
Anatomical Therapeutic Chemical (ATC) classification [BR:br08303]
J ANTIINFECTIVES FOR SYSTEMIC USE
J01 ANTIBACTERIALS FOR SYSTEMIC USE
J01C BETA-LACTAM ANTIBACTERIALS, PENICILLINS
J01CF Beta-lactamase resistant penicillins
J01CF06 Nafcillin
D00928 Nafcillin sodium (USP) <US>
USP drug classification [BR:br08302]
Antibacterials
Beta-lactam, Penicillins
Nafcillin
D00928 Nafcillin sodium (USP)
Drug groups [BR:br08330]
Antibacterial
DG01710 beta-Lactam antibiotic
DG01713 Penicillin skeleton group
DG01480 Penicillin
DG00544 Nafcillin
D00928 Nafcillin sodium
DG01779 beta-Lactamase resistant penicillin
DG00544 Nafcillin
D00928 Nafcillin sodium
Drug classes [BR:br08332]
Antibacterial
DG01480 Penicillin
D00928 Nafcillin sodium
Antimicrobials [BR:br08307]
Antibacterials
Cell wall biosynthesis inhibitor, beta-lactam
beta-Lactamase resistant penicillin
D00928 Nafcillin sodium (USP) <US>
Drug groups [BR:br08330]
Antibacterial
DG01710 beta-Lactam antibiotic
DG01713 Penicillin skeleton group
DG01480 Penicillin
DG00544 Nafcillin
DG01779 beta-Lactamase resistant penicillin
DG00544 Nafcillin
Antimicrobials abbreviations [BR:br08327]
Antibacterials
Cell wall biosynthesis inhibitor, beta-lactam
beta-Lactamase resistant penicillin
DG00544 Nafcillin
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| Other DBs |
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| LinkDB |
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| KCF data |
ATOM 31
1 C1y C 12.9493 -12.7967
2 C5x C 12.9493 -14.1867
3 N1y N 14.3393 -14.1867
4 C1y C 14.3393 -12.7967
5 C1y C 15.6598 -14.6036
6 C1z C 16.4938 -13.4916
7 S2x S 15.6598 -12.3797
8 C1a C 17.4668 -14.4647
9 C1a C 17.4668 -12.5187
10 C6a C 16.1463 -15.9937
11 O6a O 17.5362 -15.9937 #-
12 O6a O 15.3123 -17.1057
13 N1b N 11.7679 -12.1017
14 C5a C 10.5863 -12.7967
15 O5x O 11.7679 -14.8817
16 O5a O 10.5863 -14.1867
17 C8y C 9.3354 -12.1017
18 C8y C 9.3354 -10.7118
19 C8x C 8.1229 -10.0118
20 C8x C 6.9105 -10.7118
21 C8y C 6.9105 -12.1017
22 C8y C 8.1229 -12.8017
23 C8x C 5.6981 -12.8017
24 C8x C 5.6981 -14.2017
25 C8x C 6.9105 -14.9017
26 C8x C 8.1229 -14.2017
27 O2a O 10.5294 -10.0222
28 C1b C 10.5294 -8.6222
29 C1a C 11.7247 -7.9316
30 Z Na 19.1347 -16.0631 #+
31 O0 O 22.5627 -13.7401
BOND 32
1 1 2 1
2 2 3 1
3 3 4 1
4 1 4 1
5 3 5 1
6 5 6 1
7 6 7 1
8 4 7 1
9 6 8 1
10 6 9 1
11 5 10 1 #Down
12 10 11 1
13 10 12 2
14 1 13 1 #Up
15 13 14 1
16 2 15 2
17 14 16 2
18 14 17 1
19 17 18 1
20 18 19 2
21 19 20 1
22 20 21 2
23 21 22 1
24 17 22 2
25 21 23 1
26 23 24 2
27 24 25 1
28 25 26 2
29 22 26 1
30 18 27 1
31 27 28 1
32 28 29 1
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