| Entry |
|
|---|
| Name |
Risedronate sodium (USP);
Actonel (TN) |
|---|
| Product |
|
|---|
| Generic |
|
|---|
| Formula |
C7H10NO7P2. Na
|
|---|
| Exact mass |
304.9830
|
|---|
| Mol weight |
305.09
|
|---|
| Structure |
|
|---|
| Simcomp |
|
|---|
| Class |
Musculo-skeletal system agent
DG03232 Osteoporosis agent
DG01600 Bisphosphonate
|
|---|
| Remark |
| Product (DG00786): | D00942<US> D03234<JP/US> D11570<US> |
|
|---|
| Efficacy |
Antiresorptive, Osteoporosis agent, Farnesylpyrophosphate synthetase inhibitor |
|---|
| Disease |
Osteoporosis [DS: H01593] Glucocorticoid-induced osteoporosis [DS: H01709] Paget's disease of bone [DS: H00437] |
|---|
| Comment |
Bisphosphonate
|
|---|
| Target |
|
|---|
| Pathway |
| hsa00900 | Terpenoid backbone biosynthesis |
|
|---|
| Interaction |
|
|---|
| Structure map |
|
|---|
| Brite |
Anatomical Therapeutic Chemical (ATC) classification [BR:br08303]
M MUSCULO-SKELETAL SYSTEM
M05 DRUGS FOR TREATMENT OF BONE DISEASES
M05B DRUGS AFFECTING BONE STRUCTURE AND MINERALIZATION
M05BA Bisphosphonates
M05BA07 Risedronic acid
D00942 Risedronate sodium (USP) <US>
USP drug classification [BR:br08302]
Metabolic Bone Disease Agents
Bisphosphonates
Risedronate
D00942 Risedronate sodium (USP)
Drug groups [BR:br08330]
Musculo-skeletal system agent
DG03232 Osteoporosis agent
DG01600 Bisphosphonate
DG00786 Risedronic acid
D00942 Risedronate sodium
Drug classes [BR:br08332]
Musculo-skeletal system agent
DG03232 Osteoporosis agent
D00942 Risedronate sodium
Target-based classification of drugs [BR:br08310]
Enzymes
Transferases (EC2)
Alkyl/Aryl transferases
FDPS
D00942 Risedronate sodium (USP) <US>
Drug groups [BR:br08330]
Musculo-skeletal system agent
DG03232 Osteoporosis agent
DG01600 Bisphosphonate
DG00786 Risedronic acid
|
|---|
| Other DBs |
|
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| LinkDB |
|
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| KCF data |
ATOM 18
1 Z Na 27.2473 -25.1833 #+
2 C1d C 23.2400 -23.8700
3 P1b P 24.4300 -24.5000
4 P1b P 22.0500 -24.5000
5 C1b C 23.2400 -22.5400
6 C8y C 24.4300 -21.8400
7 C8x C 25.5500 -22.5400
8 N5x N 26.7400 -21.8400
9 C8x C 26.7400 -20.4400
10 C8x C 25.5500 -19.7400
11 C8x C 24.4300 -20.4400
12 O1c O 20.8600 -23.8700
13 O1c O 22.0500 -25.9000
14 O1c O 20.5100 -25.4800
15 O1c O 25.5500 -23.8700
16 O1c O 24.4300 -25.9000
17 O1c O 25.5500 -25.2000 #-
18 O1a O 23.2400 -25.2700
BOND 17
1 2 3 1
2 2 4 1
3 2 5 1
4 5 6 1
5 6 7 2
6 7 8 1
7 8 9 2
8 9 10 1
9 10 11 2
10 6 11 1
11 4 12 2
12 4 13 1
13 4 14 1
14 3 15 2
15 3 16 1
16 3 17 1
17 2 18 1
|
|---|
