Entry |
|
Name |
Prednisolone acetate (JP18/USP/INN); Econopred (TN); Pred forte (TN) |
Product |
|
Generic |
|
Formula |
C23H30O6
|
Exact mass |
402.2042
|
Mol weight |
402.4807
|
Structure |

|
Simcomp |
|
Class |
|
Remark |
Therapeutic category: | 1315 |
Product (DG00093): | D00472<JP/US> D00980<JP/US> D00981<JP/US> D01239<JP> D03301<JP> |
Product (mixture): | D11699<US> |
|
Efficacy |
Anti-inflammatory, Glucocorticoid receptor agonist |
Target |
|
Pathway |
hsa04080 | Neuroactive ligand-receptor interaction |
|
Interaction |
|
Structure map |
map07225 | Glucocorticoid and mineralocorticoid receptor agonists/antagonists |
|
Brite |
Anatomical Therapeutic Chemical (ATC) classification [BR:br08303]
A ALIMENTARY TRACT AND METABOLISM
A01 STOMATOLOGICAL PREPARATIONS
A01A STOMATOLOGICAL PREPARATIONS
A01AC Corticosteroids for local oral treatment
A01AC04 Prednisolone
D00980 Prednisolone acetate (JP18/USP/INN) <JP/US>
A07 ANTIDIARRHEALS, INTESTINAL ANTIINFLAMMATORY/ANTIINFECTIVE AGENTS
A07E INTESTINAL ANTIINFLAMMATORY AGENTS
A07EA Corticosteroids acting locally
A07EA01 Prednisolone
D00980 Prednisolone acetate (JP18/USP/INN) <JP/US>
C CARDIOVASCULAR SYSTEM
C05 VASOPROTECTIVES
C05A AGENTS FOR TREATMENT OF HEMORRHOIDS AND ANAL FISSURES FOR TOPICAL USE
C05AA Corticosteroids
C05AA04 Prednisolone
D00980 Prednisolone acetate (JP18/USP/INN) <JP/US>
D DERMATOLOGICALS
D07 CORTICOSTEROIDS, DERMATOLOGICAL PREPARATIONS
D07A CORTICOSTEROIDS, PLAIN
D07AA Corticosteroids, weak (group I)
D07AA03 Prednisolone
D00980 Prednisolone acetate (JP18/USP/INN) <JP/US>
D07X CORTICOSTEROIDS, OTHER COMBINATIONS
D07XA Corticosteroids, weak, other combinations
D07XA02 Prednisolone
D00980 Prednisolone acetate (JP18/USP/INN) <JP/US>
H SYSTEMIC HORMONAL PREPARATIONS, EXCL. SEX HORMONES AND INSULINS
H02 CORTICOSTEROIDS FOR SYSTEMIC USE
H02A CORTICOSTEROIDS FOR SYSTEMIC USE, PLAIN
H02AB Glucocorticoids
H02AB06 Prednisolone
D00980 Prednisolone acetate (JP18/USP/INN) <JP/US>
R RESPIRATORY SYSTEM
R01 NASAL PREPARATIONS
R01A DECONGESTANTS AND OTHER NASAL PREPARATIONS FOR TOPICAL USE
R01AD Corticosteroids
R01AD02 Prednisolone
D00980 Prednisolone acetate (JP18/USP/INN) <JP/US>
S SENSORY ORGANS
S01 OPHTHALMOLOGICALS
S01B ANTIINFLAMMATORY AGENTS
S01BA Corticosteroids, plain
S01BA04 Prednisolone
D00980 Prednisolone acetate (JP18/USP/INN) <JP/US>
S01C ANTIINFLAMMATORY AGENTS AND ANTIINFECTIVES IN COMBINATION
S01CB Corticosteroids/antiinfectives/mydriatics in combination
S01CB02 Prednisolone
D00980 Prednisolone acetate (JP18/USP/INN) <JP/US>
S02 OTOLOGICALS
S02B CORTICOSTEROIDS
S02BA Corticosteroids
S02BA03 Prednisolone
D00980 Prednisolone acetate (JP18/USP/INN) <JP/US>
S03 OPHTHALMOLOGICAL AND OTOLOGICAL PREPARATIONS
S03B CORTICOSTEROIDS
S03BA Corticosteroids
S03BA02 Prednisolone
D00980 Prednisolone acetate (JP18/USP/INN) <JP/US>
USP drug classification [BR:br08302]
Hormonal Agents, Stimulant/Replacement/Modifying (Adrenal)
Prednisolone
D00980 Prednisolone acetate (JP18/USP/INN)
Ophthalmic Agents
Ophthalmic Anti-inflammatories
Glucocorticoids, Ophthalmic
Prednisolone
D00980 Prednisolone acetate (JP18/USP/INN)
Therapeutic category of drugs in Japan [BR:br08301]
1 Agents affecting nervous system and sensory organs
13 Agents affecting sensory organs
131 Ophthalmic agents
1315 Ophthalmic cortisones
D00980 Prednisolone acetate (JP18/USP/INN)
Classification of Japanese OTC drugs [BR:br08313]
Agents for urogenital organs and anus
30 Hemorrhoid drugs for external use
D00980 Prednisolone acetate (JP18/USP/INN)
Agents for integumentary system
57 Analgesic, antipruritic, astringent, and anti-inflammatory remedies (incl. gel patches)
D00980 Prednisolone acetate (JP18/USP/INN)
Risk category of Japanese OTC drugs [BR:br08312]
Designated second-class OTC drugs
Inorganic and organic chemicals
Prednisolone acetate
D00980 Prednisolone acetate (JP18/USP/INN)
Second-class OTC drugs
Inorganic and organic chemicals
Prednisolone acetate
D00980 Prednisolone acetate (JP18/USP/INN)
Drug groups [BR:br08330]
Anti-inflammatory
DG01955 Corticosteroid
DG02068 Glucocorticoid
DG00093 Prednisolone
D00980 Prednisolone acetate
Drug classes [BR:br08332]
Anti-inflammatory
DG01955 Corticosteroid
D00980 Prednisolone acetate
Target-based classification of drugs [BR:br08310]
Nuclear receptors
Estrogen like receptors
3-Ketosteroid receptor
NR3C1 (GR)
D00980 Prednisolone acetate (JP18/USP/INN) <JP/US>
Drugs listed in the Japanese Pharmacopoeia [BR:br08311]
Chemicals
D00980 Prednisolone acetate
Drug groups [BR:br08330]
Anti-inflammatory
DG01955 Corticosteroid
DG02068 Glucocorticoid
DG00093 Prednisolone
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Other DBs |
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LinkDB |
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KCF data |
ATOM 29
1 C2x C 26.7400 -19.3900
2 C5x C 26.7400 -20.7200
3 C2x C 27.9300 -21.4200
4 C2y C 29.1200 -20.7200
5 C1z C 29.1200 -19.3900
6 C2x C 27.9300 -18.6900
7 C1x C 30.3100 -21.4200
8 C1x C 31.5000 -20.7200
9 C1y C 31.5000 -19.3900
10 C1y C 30.3100 -18.6900
11 C1y C 32.6900 -18.6900
12 C1z C 32.6900 -17.2900
13 C1x C 31.5000 -16.5900
14 C1y C 30.3100 -17.2900
15 C1x C 35.0000 -18.6900
16 C1x C 35.0000 -17.2900
17 C1z C 33.8800 -16.5900
18 O5x O 25.6200 -21.4200
19 C1a C 29.1200 -17.9900
20 O1a O 29.1200 -16.5900
21 C1a C 32.6900 -15.9600
22 C5a C 33.8800 -14.9100
23 O1a O 35.0000 -15.9600
24 C1b C 35.0000 -14.2100
25 O5a O 32.6900 -14.2100
26 O7a O 36.1900 -14.9100
27 C7a C 37.3800 -14.2100
28 C1a C 38.5000 -14.9100
29 O6a O 37.3800 -12.8800
BOND 32
1 1 2 1
2 2 3 1
3 3 4 2
4 4 5 1
5 5 6 1
6 1 6 2
7 4 7 1
8 7 8 1
9 8 9 1
10 9 10 1
11 5 10 1
12 9 11 1
13 11 12 1
14 12 13 1
15 13 14 1
16 10 14 1
17 11 15 1
18 15 16 1
19 16 17 1
20 12 17 1
21 2 18 2
22 5 19 1 #Up
23 14 20 1 #Up
24 12 21 1 #Up
25 17 22 1 #Up
26 17 23 1 #Down
27 22 24 1
28 22 25 2
29 24 26 1
30 26 27 1
31 27 28 1
32 27 29 2
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