| Entry |
|
|---|
| Name |
Oxymetazoline hydrochloride (JAN/USP);
Ocuclear (TN);
Rhfade (TN) |
|---|
| Product |
|
|---|
| Generic |
|
|---|
| Formula |
C16H24N2O. HCl
|
|---|
| Exact mass |
296.1655
|
|---|
| Mol weight |
296.83
|
|---|
| Structure |
|
|---|
| Simcomp |
|
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| Class |
Cardiovascular agent
DG01456 Adrenergic receptor agonist
DG01450 alpha-Adrenergic receptor agonist
DG01448 alpha1-Adrenergic receptor agonist
|
|---|
| Remark |
| Product (DG01029): | D01022<US> |
|
|---|
| Efficacy |
Vasoconstrictor, alpha1-Adrenergic receptor agonist |
|---|
| Comment |
Imidazoline derivative
|
|---|
| Target |
|
|---|
| Pathway |
| hsa04080 | Neuroactive ligand-receptor interaction |
| hsa04270 | Vascular smooth muscle contraction |
|
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| Interaction |
|
|---|
| Brite |
Anatomical Therapeutic Chemical (ATC) classification [BR:br08303]
D DERMATOLOGICALS
D11 OTHER DERMATOLOGICAL PREPARATIONS
D11A OTHER DERMATOLOGICAL PREPARATIONS
D11AX Other dermatologicals
D11AX27 Oxymetazoline
D01022 Oxymetazoline hydrochloride (JAN/USP) <US>
R RESPIRATORY SYSTEM
R01 NASAL PREPARATIONS
R01A DECONGESTANTS AND OTHER NASAL PREPARATIONS FOR TOPICAL USE
R01AA Sympathomimetics, plain
R01AA05 Oxymetazoline
D01022 Oxymetazoline hydrochloride (JAN/USP) <US>
R01AB Sympathomimetics, combinations excl. corticosteroids
R01AB07 Oxymetazoline
D01022 Oxymetazoline hydrochloride (JAN/USP) <US>
S SENSORY ORGANS
S01 OPHTHALMOLOGICALS
S01G DECONGESTANTS AND ANTIALLERGICS
S01GA Sympathomimetics used as decongestants
S01GA04 Oxymetazoline
D01022 Oxymetazoline hydrochloride (JAN/USP) <US>
USP drug classification [BR:br08302]
Dermatological Agents
Acne and Rosacea Agents
Acne and Rosacea Agents, Other
Oxymetazoline
D01022 Oxymetazoline hydrochloride (JAN/USP)
Ophthalmic Agents
Ophthalmic Agents, Other
Oxymetazoline
D01022 Oxymetazoline hydrochloride (JAN/USP)
Classification of Japanese OTC drugs [BR:br08313]
Agents for otolaryngologic use
70 Nasal sprays for inflammation
D01022 Oxymetazoline hydrochloride (JAN/USP)
Risk category of Japanese OTC drugs [BR:br08312]
Second-class OTC drugs
Inorganic and organic chemicals
Oxymetazoline
D01022 Oxymetazoline hydrochloride (JAN/USP)
Drug groups [BR:br08330]
Cardiovascular agent
DG01456 Adrenergic receptor agonist
DG01450 alpha-Adrenergic receptor agonist
DG01448 alpha1-Adrenergic receptor agonist
DG01029 Oxymetazoline
D01022 Oxymetazoline hydrochloride
Target-based classification of drugs [BR:br08310]
G Protein-coupled receptors
Rhodopsin family
Adrenaline
ADRA1A
D01022 Oxymetazoline hydrochloride (JAN/USP) <US>
Rx-to-OTC switch list in the USA [br08315.html]
D01022
Rx-to-OTC switch list in Japan [br08314.html]
D01022
Drug groups [BR:br08330]
Cardiovascular agent
DG01456 Adrenergic receptor agonist
DG01450 alpha-Adrenergic receptor agonist
DG01448 alpha1-Adrenergic receptor agonist
DG01029 Oxymetazoline
|
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| Other DBs |
|
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| LinkDB |
|
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| KCF data |
ATOM 20
1 X Cl 27.5100 -25.9000
2 C8y C 21.1400 -21.2100
3 C8y C 21.1400 -22.6100
4 C8y C 22.3524 -23.3100
5 C8x C 23.5649 -22.6100
6 C8y C 23.5649 -21.2100
7 C8y C 22.3524 -20.5100
8 C1b C 22.3524 -19.1102
9 C2y C 23.5480 -18.4198
10 N1x N 24.8536 -18.8359
11 C1x C 25.6555 -17.7246
12 C1x C 24.8464 -16.6186
13 N2x N 23.5444 -17.0463
14 C1a C 24.7960 -20.4990
15 C1a C 19.9276 -20.5100
16 O1a O 19.9276 -23.3100
17 C1d C 22.3524 -24.7098
18 C1a C 23.7524 -24.7098
19 C1a C 20.9524 -24.7098
20 C1a C 22.3524 -26.1098
BOND 20
1 2 3 2
2 3 4 1
3 4 5 2
4 5 6 1
5 6 7 2
6 2 7 1
7 7 8 1
8 8 9 1
9 9 10 1
10 10 11 1
11 11 12 1
12 12 13 1
13 9 13 2
14 6 14 1
15 2 15 1
16 3 16 1
17 4 17 1
18 17 18 1
19 17 19 1
20 17 20 1
|
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