| Entry |
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| Name |
Butenafine hydrochloride (JP18/USAN);
Mentax (TN);
Volley (TN) |
|---|
| Formula |
C23H27N. HCl
|
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| Exact mass |
353.1910
|
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| Mol weight |
353.93
|
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| Structure |
|
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| Simcomp |
|
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| Remark |
| Therapeutic category: | 2659 |
| Product (DG00378): | D01093<JP> |
|
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| Efficacy |
Antifungal, Ergosterol biosynthesis inhibitor |
|---|
| Disease |
Tinea (pityriasis) versicolor [DS: H01334] |
|---|
| Comment |
Benzylamine derivative
|
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| Target |
squalene epoxidase [KO: K00511] |
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| Pathway |
|
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| Structure map |
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| Brite |
Anatomical Therapeutic Chemical (ATC) classification [BR:br08303]
D DERMATOLOGICALS
D01 ANTIFUNGALS FOR DERMATOLOGICAL USE
D01A ANTIFUNGALS FOR TOPICAL USE
D01AE Other antifungals for topical use
D01AE23 Butenafine
D01093 Butenafine hydrochloride (JP18/USAN) <JP>
USP drug classification [BR:br08302]
Dermatological Agents
Topical Anti-infectives
Antifungals, dermatological
Butenafine
D01093 Butenafine hydrochloride (JP18/USAN)
Therapeutic category of drugs in Japan [BR:br08301]
2 Agents affecting individual organs
26 Epidermides
265 Antiparasitic dermatosis agents
2659 Others
D01093 Butenafine hydrochloride (JP18/USAN)
Classification of Japanese OTC drugs [BR:br08313]
Agents for integumentary system
58 Ringworm drugs
D01093 Butenafine hydrochloride (JP18/USAN)
Risk category of Japanese OTC drugs [BR:br08312]
Designated second-class OTC drugs
Inorganic and organic chemicals
Butenafine
D01093 Butenafine hydrochloride (JP18/USAN)
Second-class OTC drugs
Inorganic and organic chemicals
Butenafine
D01093 Butenafine hydrochloride (JP18/USAN)
Antimicrobials [BR:br08307]
Antifungals
Ergosterol biosynthesis inhibitor
Other ergosterol biosynthesis inhibitor
D01093 Butenafine hydrochloride (JP18/USAN) <JP>
Drugs listed in the Japanese Pharmacopoeia [BR:br08311]
Chemicals
D01093 Butenafine hydrochloride
D01093 Butenafine hydrochloride solution
D01093 Butenafine hydrochloride spray
D01093 Butenafine hydrochloride cream
Rx-to-OTC switch list in the USA [br08315.html]
D01093
Rx-to-OTC switch list in Japan [br08314.html]
D01093
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| Other DBs |
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| LinkDB |
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| KCF data |
ATOM 25
1 C8x C 18.4139 -17.1211
2 C8x C 18.4139 -18.5242
3 C8x C 19.6290 -19.2258
4 C8y C 20.8442 -18.5242
5 C8y C 20.8442 -17.1211
6 C8x C 19.6290 -16.4196
7 C8x C 22.0593 -19.2258
8 C8x C 23.2745 -18.5242
9 C8x C 23.2745 -17.1211
10 C8y C 22.0593 -16.4196
11 C1b C 22.0593 -15.0164
12 N1c N 23.2766 -14.3137
13 C1b C 24.4758 -15.0062
14 C1a C 23.2766 -12.9119
15 C8y C 25.6653 -14.3195
16 C8x C 26.8594 -15.0092
17 C8x C 28.0746 -14.3077
18 C8y C 28.0748 -12.9046
19 C8x C 26.8807 -12.2150
20 C8x C 25.6655 -12.9163
21 C1d C 29.3024 -12.1959
22 C1a C 30.5176 -11.4944
23 C1a C 30.0065 -13.4155
24 C1a C 28.6035 -10.9854
25 X Cl 30.3101 -17.1500
BOND 26
1 1 2 2
2 2 3 1
3 3 4 2
4 4 5 1
5 5 6 2
6 1 6 1
7 4 7 1
8 7 8 2
9 8 9 1
10 9 10 2
11 5 10 1
12 10 11 1
13 11 12 1
14 12 13 1
15 12 14 1
16 13 15 1
17 15 16 2
18 16 17 1
19 17 18 2
20 18 19 1
21 19 20 2
22 15 20 1
23 18 21 1
24 21 22 1
25 21 23 1
26 21 24 1
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