KEGG   DRUG: NadifloxacinHelp
Entry
D01147                      Drug                                   

Name
Nadifloxacin (JAN/INN);
NDFX;
Acuatim (TN)
Formula
C19H21FN2O4
Exact mass
360.1485
Mol weight
360.3794
Structure
Mol fileKCF fileDB search
Class
Antibacterial
 DG01550  Quinolone
  DG01549  Fluoroquinolone
Other
 DG01529  Topoisomerase inhibitor
  DG01528  Topoisomerase IV inhibitor
Remark
Therapeutic category: 2639
ATC code: D10AF05
Product: D01147<JP>
Efficacy
Antibacterial, Nucleic acid biosynthesis inhibitor
Comment
Fluoroquinolones
Target
DNA gyrase [KO:K02469 K02470]
Interaction
Drug interaction
Brite
Anatomical Therapeutic Chemical (ATC) classification [BR:br08303]
 D DERMATOLOGICALS
  D10 ANTI-ACNE PREPARATIONS
   D10A ANTI-ACNE PREPARATIONS FOR TOPICAL USE
    D10AF Antiinfectives for treatment of acne
     D10AF05 Nadifloxacin
      D01147  Nadifloxacin (JAN/INN) <JP>
Therapeutic category of drugs in Japan [BR:br08301]
 2  Agents affecting individual organs
  26  Epidermides
   263  Suppurative dermatosis agents
    2639  Others
     D01147  Nadifloxacin (JAN/INN)
Antiinfectives [br08350.html]
 Antibacterials
  D01147
BRITE hierarchy
Other DBs
CAS: 124858-35-1
PubChem: 7848210
ChEBI: 31889
ChEMBL: CHEMBL363449
LigandBox: D01147
NIKKAJI: J282.958D
LinkDB All DBs
KCF data Show

ATOM        26
            1   C8y C    20.9300  -15.1200
            2   C8y C    20.9300  -16.5200
            3   C8x C    22.1200  -14.4200
            4   C8y C    23.3100  -15.1200
            5   C8x C    25.7600  -16.5200
            6   C8y C    25.7600  -15.1200
            7   C8y C    24.5700  -14.4200
            8   C8y C    23.3100  -16.5200
            9   C8y C    22.1200  -17.2200
            10  C1x C    22.1200  -18.6200
            11  C1x C    23.3100  -19.3200
            12  C1y C    24.5000  -18.6200
            13  N4y N    24.5000  -17.2200
            14  C6a C    26.9500  -14.4200
            15  O6a O    28.2100  -15.1200
            16  O6a O    26.9500  -13.0200
            17  O5x O    24.5700  -13.0200
            18  X   F    19.6700  -14.4200
            19  N1y N    19.6700  -17.2200
            20  C1a C    25.7600  -19.3200
            21  C1x C    18.4800  -16.5200
            22  C1x C    17.2900  -17.2200
            23  C1y C    17.2900  -18.6200
            24  C1x C    18.4800  -19.3200
            25  C1x C    19.6700  -18.6200
            26  O1a O    16.0300  -19.3200
BOND        29
            1    11  12 1
            2    12  13 1
            3    13   8 1
            4    13   5 1
            5     6  14 1
            6     5   6 2
            7    14  15 1
            8     6   7 1
            9    14  16 2
            10    7   4 1
            11    7  17 2
            12    3   1 2
            13    1  18 1
            14    2  19 1
            15    1   2 1
            16   12  20 1
            17    2   9 2
            18    4   3 1
            19    4   8 2
            20    8   9 1
            21    9  10 1
            22   19  21 1
            23   21  22 1
            24   22  23 1
            25   23  24 1
            26   24  25 1
            27   25  19 1
            28   10  11 1
            29   23  26 1

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