| Entry |
|
|---|
| Name |
Cefepime hydrochloride (USP);
Cefepime dihydrochloride hydrate (JP18);
Maxipime (TN) |
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| Product |
|
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| Generic |
|
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| Formula |
C19H25N6O5S2. HCl. Cl. H2O
|
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| Exact mass |
570.0889
|
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| Mol weight |
571.50
|
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| Structure |
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| Simcomp |
|
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| Class |
|
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| Remark |
| Therapeutic category: | 6132 |
| Product (DG00586): | D01157<JP/US> |
|
|---|
| Efficacy |
Antibacterial, Cell wall biosynthesis inhibitor |
|---|
| Disease |
Uncomplicated and complicated urinary tract infections [DS: H01176] |
|---|
| Target |
penicillin binding protein |
|---|
| Pathway |
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| Interaction |
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| Brite |
Anatomical Therapeutic Chemical (ATC) classification [BR:br08303]
J ANTIINFECTIVES FOR SYSTEMIC USE
J01 ANTIBACTERIALS FOR SYSTEMIC USE
J01D OTHER BETA-LACTAM ANTIBACTERIALS
J01DE Fourth-generation cephalosporins
J01DE01 Cefepime
D01157 Cefepime hydrochloride (USP) <JP/US>
USP drug classification [BR:br08302]
Antibacterials
Beta-lactam, Cephalosporins
Cefepime
D01157 Cefepime hydrochloride (USP)
Therapeutic category of drugs in Japan [BR:br08301]
6 Agents against pathologic organisms and parasites
61 Antibiotics
613 Acting mainly on gram-positive and gram-negative bacteria
6132 Cephem antibioitics
D01157 Cefepime hydrochloride (USP); Cefepime dihydrochloride hydrate (JP18)
Drug groups [BR:br08330]
Antibacterial
DG01710 beta-Lactam antibiotic
DG01714 Cephalosporin skeleton group
DG01488 Cephem
DG00586 Cefepime
D01157 Cefepime hydrochloride
DG01777 Fourth-generation cephalosporin
DG00586 Cefepime
D01157 Cefepime hydrochloride
DG01804 Oxyimino beta-lactam
DG00586 Cefepime
D01157 Cefepime hydrochloride
Drug classes [BR:br08332]
Antibacterial
DG01488 Cephem
D01157 Cefepime hydrochloride
Antimicrobials [BR:br08307]
Antibacterials
Cell wall biosynthesis inhibitor, beta-lactam
Fourth-generation cephalosporin
D01157 Cefepime hydrochloride (USP) <JP/US>
Drugs listed in the Japanese Pharmacopoeia [BR:br08311]
Chemicals
D01157 Cefepime dihydrochloride hydrate
D01157 Cefepime dihydrochloride for injection
Drug groups [BR:br08330]
Antibacterial
DG01710 beta-Lactam antibiotic
DG01714 Cephalosporin skeleton group
DG01488 Cephem
DG00586 Cefepime
DG01777 Fourth-generation cephalosporin
DG00586 Cefepime
DG01804 Oxyimino beta-lactam
DG00586 Cefepime
Antimicrobials abbreviations [BR:br08327]
Antibacterials
Cell wall biosynthesis inhibitor, beta-lactam
Fourth-generation cephalosporin
DG00586 Cefepime
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| Other DBs |
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| LinkDB |
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| KCF data |
ATOM 35
1 X Cl 19.3672 -22.6156
2 X Cl 29.6799 -18.2084 #-
3 O0 O 22.4824 -22.5456
4 C1y C 26.0672 -18.8627
5 N1y N 26.0672 -20.2534
6 C2y C 27.2717 -20.9487
7 C2y C 28.4761 -20.2534
8 C1x C 28.4761 -18.8627
9 S2x S 27.2717 -18.1673
10 C1y C 24.6764 -18.8627
11 C5x C 24.6764 -20.2534
12 N1b N 23.4722 -18.1673
13 C5a C 22.2677 -18.8627
14 O5a O 22.2677 -20.2534
15 O5x O 23.4722 -20.9487
16 C2c C 21.0633 -18.1673
17 C1b C 29.6990 -20.9598
18 C8y C 19.8396 -18.8743
19 N2y N 30.9084 -20.2618 #+
20 C8x C 18.7080 -18.0429
21 S2x S 17.5629 -18.8608
22 C8y C 17.9869 -20.2027
23 N5x N 19.3940 -20.2140
24 N2b N 21.0632 -16.7553
25 C6a C 27.2717 -22.3560
26 O6a O 28.4867 -23.0575
27 O6a O 26.0583 -23.0567
28 C1x C 30.9086 -18.8509
29 C1x C 32.2501 -20.6980
30 C1x C 33.0795 -19.5567
31 C1x C 32.2504 -18.4151
32 C1a C 30.9084 -21.6640
33 N1a N 17.1436 -21.3437
34 O2a O 22.2916 -16.0462
35 C1a C 22.2922 -14.6304
BOND 35
1 4 5 1
2 5 6 1
3 6 7 2
4 7 8 1
5 8 9 1
6 4 9 1
7 4 10 1
8 10 11 1
9 5 11 1
10 10 12 1 #Up
11 12 13 1
12 13 14 2
13 11 15 2
14 13 16 1
15 7 17 1
16 16 18 1
17 17 19 1
18 18 20 2
19 20 21 1
20 21 22 1
21 22 23 2
22 18 23 1
23 16 24 2
24 6 25 1
25 25 26 1
26 25 27 2
27 19 28 1
28 19 29 1
29 29 30 1
30 30 31 1
31 28 31 1
32 19 32 1
33 22 33 1
34 24 34 1
35 34 35 1
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