| Entry |
|
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| Name |
Aluminum clofibrate (JAN/INN);
Alfibrate (TN) |
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| Formula |
C20H21AlCl2O7
|
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| Exact mass |
470.0480
|
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| Mol weight |
471.26
|
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| Structure |
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| Simcomp |
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| Class |
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| Remark |
| Product (DG00358): | D00279<JP> |
|
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| Efficacy |
Antihyperlipidemic, Triglyceride synthesis inhibitor, Peroxisome proliferator-activated receptor (PPAR) alpha agonist |
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| Comment |
Clofibrate derivative
|
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| Target |
|
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| Pathway |
| hsa04920 | Adipocytokine signaling pathway |
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| Interaction |
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| Structure map |
| map07222 | Peroxisome proliferator-activated receptor (PPAR) agonists |
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| Brite |
Anatomical Therapeutic Chemical (ATC) classification [BR:br08303]
C CARDIOVASCULAR SYSTEM
C10 LIPID MODIFYING AGENTS
C10A LIPID MODIFYING AGENTS, PLAIN
C10AB Fibrates
C10AB01 Clofibrate
D01208 Aluminum clofibrate (JAN/INN)
C10AB03 Aluminium clofibrate
D01208 Aluminum clofibrate (JAN/INN)
Drug groups [BR:br08330]
Hypolipidemic agent
DG01946 Hypolipidemic agent
DG01733 PPAR alpha agonist
DG01547 Fibrate
DG00358 Clofibrate
D01208 Aluminum clofibrate
Target-based classification of drugs [BR:br08310]
Nuclear receptors
Thyroid hormone like receptors
Peroxisome proliferator-activated receptor (PPAR)
NR1C1 (PPARA)
D01208 Aluminum clofibrate (JAN/INN)
Drug groups [BR:br08330]
Hypolipidemic agent
DG01946 Hypolipidemic agent
DG01733 PPAR alpha agonist
DG01547 Fibrate
DG00358 Clofibrate
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| Other DBs |
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| LinkDB |
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| KCF data |
ATOM 30
1 C8y C 15.1737 -17.3526
2 O2a O 16.3854 -16.6511
3 C1d C 17.5971 -17.3455
4 C7a C 18.8087 -16.6440
5 O7a O 20.0204 -17.3385
6 Z Al 21.2321 -16.6370
7 O7a O 22.4437 -17.3314
8 C7a C 23.6554 -16.6299
9 C1d C 24.8671 -17.3242
10 O2a O 26.0787 -16.6227
11 C8y C 27.2904 -17.3172
12 C1a C 16.5980 -18.3376
13 C1a C 18.5892 -18.3376
14 O6a O 18.8057 -15.2410
15 O1a O 21.2290 -15.2340
16 O6a O 23.6523 -15.2269
17 C1a C 23.8680 -18.3163
18 C1a C 25.8592 -18.3163
19 C8x C 27.2950 -18.7138
20 C8x C 28.5067 -19.4081
21 C8y C 29.7137 -18.7059
22 C8x C 29.7093 -17.3094
23 C8x C 28.4977 -16.6151
24 C8x C 13.9604 -16.6540
25 C8x C 12.7487 -17.3555
26 C8y C 12.7504 -18.7556
27 C8x C 13.9638 -19.4542
28 C8x C 15.1754 -18.7527
29 X Cl 11.5363 -19.4586
30 X Cl 30.9310 -19.4037
BOND 31
1 7 8 1
2 8 16 2
3 9 17 1
4 8 9 1
5 9 18 1
6 4 5 1
7 9 10 1
8 2 3 1
9 10 11 1
10 5 6 1
11 11 19 2
12 19 20 1
13 20 21 2
14 21 22 1
15 22 23 2
16 23 11 1
17 3 12 1
18 1 2 1
19 3 13 1
20 6 7 1
21 4 14 2
22 1 24 2
23 24 25 1
24 25 26 2
25 26 27 1
26 27 28 2
27 28 1 1
28 3 4 1
29 26 29 1
30 6 15 1
31 21 30 1
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