| Entry |
|
|---|
| Name |
Novobiocin sodium (JAN/USP);
Albamycin (TN) |
|---|
| Formula |
C31H35N2O11. Na
|
|---|
| Exact mass |
634.2139
|
|---|
| Mol weight |
634.60
|
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| Structure |
|
|---|
| Simcomp |
|
|---|
| Source |
Streptomyces caeruleus [TAX: 195949]
|
|---|
| Class |
Transporter inhibitor
DG02901 SLC22A6 inhibitor
DG02866 SLC22A8 inhibitor
|
|---|
| Remark |
|
|---|
| Efficacy |
Antibacterial |
|---|
| Comment |
Natural product
|
|---|
| Target |
|
|---|
| Interaction |
Transporter inhibition: SLC22A6 [HSA: 9356], SLC22A8 [HSA: 9376]
|
|---|
| Brite |
Drug groups [BR:br08330]
Transporter inhibitor
DG02901 SLC22A6 inhibitor
D01209 Novobiocin sodium
DG02866 SLC22A8 inhibitor
D01209 Novobiocin sodium
Antimicrobials [BR:br08307]
Antibacterials
Nucleic acid synthesis inhibitor
Fluoroquinolone
D01209 Novobiocin sodium (JAN/USP)
Antimicrobials abbreviations [BR:br08327]
Antibacterials
Nucleic acid synthesis inhibitor
Fluoroquinolone
D01209 Novobiocin sodium (JAN/USP)
Drug metabolizing enzymes and transporters [br08309.html]
Drug transporters
D01209
|
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| Other DBs |
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| LinkDB |
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| KCF data |
ATOM 45
1 C8y C 23.5387 -13.9584
2 C8y C 23.5387 -15.3531
3 C8y C 22.3329 -13.2669
4 O7x O 24.7503 -13.2495
5 C8y C 24.7563 -16.0503
6 C8x C 22.3329 -16.0561
7 C8y C 21.1331 -13.9584
8 C1a C 22.3272 -11.8896
9 C8y C 25.9678 -13.9467
10 C8y C 25.9794 -15.3588
11 O1a O 24.7563 -17.4333 #-
12 C8x C 21.1331 -15.3531
13 O2a O 19.9388 -13.2728
14 O6a O 27.1549 -13.2552
15 N1b N 27.5863 -15.9616
16 C1y C 18.7520 -13.9641
17 C5a C 28.7862 -15.2703
18 C1y C 18.7520 -15.3588
19 O2x O 17.5402 -13.2728
20 C8y C 29.9804 -15.9616
21 O5a O 28.7862 -13.8930
22 C1y C 17.5402 -16.0620
23 O1a O 19.9447 -16.0446
24 C1z C 16.3462 -13.9641
25 C8x C 29.9862 -17.3446
26 C8x C 31.1615 -15.2760
27 C1y C 16.3462 -15.3588
28 O7a O 17.5402 -17.4450
29 C1a C 15.5253 -12.5275
30 C1a C 14.9223 -14.2416
31 C8y C 31.1673 -18.0361
32 C8x C 32.3615 -15.9559
33 O2a O 15.1462 -16.0446
34 C7a C 16.3403 -18.1306
35 C8y C 32.3674 -17.3389
36 C1b C 31.1673 -19.4121
37 C1a C 13.7399 -16.0503
38 N1a N 16.3346 -19.5008
39 O6a O 15.1462 -17.4393
40 O1a O 33.5614 -18.0175
41 C2b C 32.3674 -20.1037
42 C2c C 32.3674 -21.4808
43 C1a C 33.5614 -22.1724
44 C1a C 31.1673 -22.1724
45 Z Na 36.4428 -16.9586 #+
BOND 47
1 1 2 2
2 1 3 1
3 1 4 1
4 2 5 1
5 2 6 1
6 3 7 2
7 3 8 1
8 4 9 1
9 5 10 2
10 5 11 1
11 6 12 2
12 7 13 1
13 9 14 2
14 10 15 1
15 16 13 1 #Up
16 15 17 1
17 16 18 1
18 16 19 1
19 17 20 1
20 17 21 2
21 18 22 1
22 18 23 1 #Down
23 19 24 1
24 20 25 1
25 20 26 2
26 22 27 1
27 22 28 1 #Down
28 24 29 1
29 24 30 1
30 25 31 2
31 26 32 1
32 27 33 1 #Up
33 28 34 1
34 31 35 1
35 31 36 1
36 33 37 1
37 34 38 1
38 34 39 2
39 35 40 1
40 36 41 1
41 41 42 2
42 42 43 1
43 42 44 1
44 7 12 1
45 9 10 1
46 24 27 1
47 32 35 2
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