| Entry |
|
|---|
| Name |
Leucovorin calcium (USP);
Calcium folinate (JP18);
Uzel (TN);
Wellcovorin (TN) |
|---|
| Product |
|
|---|
| Generic |
LEUCOVORIN CALCIUM (American Health Packaging), LEUCOVORIN CALCIUM (BluePoint Laboratories), LEUCOVORIN CALCIUM (Epic Pharma LLC), LEUCOVORIN CALCIUM (Fresenius Kabi USA), LEUCOVORIN CALCIUM (Fresenius Kabi USA), LEUCOVORIN CALCIUM (Fresenius Kabi USA), LEUCOVORIN CALCIUM (Fresenius Kabi USA), LEUCOVORIN CALCIUM (Hikma Pharmaceuticals USA), LEUCOVORIN CALCIUM (Hikma Pharmaceuticals USA), LEUCOVORIN CALCIUM (Ingenus Pharmaceuticals), LEUCOVORIN CALCIUM (Leading Pharma), LEUCOVORIN CALCIUM (Major Pharmaceuticals), LEUCOVORIN CALCIUM (Mylan Institutional), LEUCOVORIN CALCIUM (Mylan Institutional LLC), LEUCOVORIN CALCIUM (Proficient Rx LP), LEUCOVORIN CALCIUM (Sagent Pharmaceuticals), LEUCOVORIN CALCIUM (Sagent Pharmaceuticals), LEUCOVORIN CALCIUM (Teva Parenteral Medicines), LEUCOVORIN CALCIUM (Teva Parenteral Medicines), LEUCOVORIN CALCIUM (Teva Pharmaceuticals USA), LEUCOVORIN CALCIUM (West-Ward Pharmaceuticals Corp.) |
|---|
| Formula |
C20H21N7O7. Ca
|
|---|
| Exact mass |
511.1128
|
|---|
| Mol weight |
511.5014
|
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| Structure |
|
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| Simcomp |
|
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| Remark |
| Therapeutic category: | 3929 |
| Product (DG02073): | D01211<JP/US> |
|
|---|
| Efficacy |
Anti-anemic (folate deficiency), Antidote (antifolate), Antineoplastic (enhancer), Supplement (folic acid) |
|---|
| Disease |
|
|---|
| Comment |
Tetrahydrofolic acid [CPD: C00101] derivative
|
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| Interaction |
|
|---|
| Brite |
Anatomical Therapeutic Chemical (ATC) classification [BR:br08303]
V VARIOUS
V03 ALL OTHER THERAPEUTIC PRODUCTS
V03A ALL OTHER THERAPEUTIC PRODUCTS
V03AF Detoxifying agents for antineoplastic treatment
V03AF03 Calcium folinate
D01211 Leucovorin calcium (USP) <JP/US>
USP drug classification [BR:br08302]
Antineoplastics
Treatment Adjuncts
Leucovorin
D01211 Leucovorin calcium (USP)
Antineoplastics, Other
Leucovorin
D01211 Leucovorin calcium (USP)
Therapeutic category of drugs in Japan [BR:br08301]
3 Agents affecting metabolism
39 Other agents affecting metabolism
392 Antidotes
3929 Others
D01211 Leucovorin calcium (USP); Calcium folinate (JP18)
Drugs listed in the Japanese Pharmacopoeia [BR:br08311]
Chemicals
D01211 Calcium folinate
|
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| Other DBs |
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| LinkDB |
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| KCF data |
ATOM 35
1 C1c C 24.0800 -14.7700
2 C1b C 25.2700 -15.4700
3 C6a C 24.0800 -13.3700
4 C8y C 11.9700 -17.6400
5 N1y N 13.1600 -16.9400
6 C8y C 11.9700 -19.0400
7 C8y C 10.7100 -16.9400
8 C1y C 14.4200 -17.6400
9 N1x N 13.1600 -19.7400
10 N4x N 10.7100 -19.7400
11 N5x N 9.5200 -17.6400
12 O5x O 10.7100 -15.5400
13 C1x C 14.4200 -19.0400
14 C1b C 15.6100 -16.9400
15 C8y C 9.5200 -19.0400
16 N1a N 8.3300 -19.7400
17 N1b N 16.8000 -17.6400
18 C8y C 17.9900 -16.9400
19 C8x C 17.9900 -15.5400
20 C8x C 19.1800 -14.8400
21 C8y C 20.4400 -15.5400
22 C8x C 20.4400 -16.9400
23 C8x C 19.2500 -17.6400
24 C5a C 21.6300 -14.8400
25 N1b N 22.8900 -15.5400
26 O5a O 21.6300 -13.4400
27 O6a O 25.2700 -12.6700 #-
28 C1b C 26.4600 -14.7700
29 O6a O 22.8900 -12.6700
30 C6a C 27.6500 -15.4700
31 O6a O 28.9100 -14.7000 #-
32 O6a O 27.6500 -16.8700
33 C4a C 13.1600 -15.5400
34 O4a O 14.3500 -14.8400
35 Z Ca 27.3000 -13.0900 #2+
BOND 36
1 1 2 1
2 1 3 1 #Down
3 4 5 1
4 4 6 2
5 4 7 1
6 5 8 1
7 6 9 1
8 6 10 1
9 7 11 1
10 7 12 2
11 8 13 1
12 8 14 1
13 10 15 1
14 15 16 1
15 9 13 1
16 11 15 2
17 14 17 1
18 17 18 1
19 18 19 2
20 19 20 1
21 20 21 2
22 21 22 1
23 22 23 2
24 18 23 1
25 21 24 1
26 24 25 1
27 24 26 2
28 1 25 1
29 3 27 1
30 2 28 1
31 3 29 2
32 28 30 1
33 30 31 1
34 30 32 2
35 5 33 1
36 33 34 2
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