| Entry |
|
|---|
| Name |
Halcinonide (JAN/USP/INN);
Halog (TN) |
|---|
| Product |
|
|---|
| Generic |
|
|---|
| Formula |
C24H32ClFO5
|
|---|
| Exact mass |
454.1922
|
|---|
| Mol weight |
454.96
|
|---|
| Structure |
|
|---|
| Simcomp |
|
|---|
| Class |
|
|---|
| Remark |
|
|---|
| Efficacy |
Anti-inflammatory (topical), Glucocorticoid receptor agonist |
|---|
| Target |
|
|---|
| Pathway |
| hsa04080 | Neuroactive ligand-receptor interaction |
|
|---|
| Interaction |
|
|---|
| Brite |
Anatomical Therapeutic Chemical (ATC) classification [BR:br08303]
D DERMATOLOGICALS
D07 CORTICOSTEROIDS, DERMATOLOGICAL PREPARATIONS
D07A CORTICOSTEROIDS, PLAIN
D07AD Corticosteroids, very potent (group IV)
D07AD02 Halcinonide
D01308 Halcinonide (JAN/USP/INN) <US>
USP drug classification [BR:br08302]
Dermatological Agents
Dermatitis and Pruitus Agents
Glucocorticoids, High Potency
Halcinonide
D01308 Halcinonide (JAN/USP/INN)
Drug groups [BR:br08330]
Anti-inflammatory
DG01955 Corticosteroid
DG02068 Glucocorticoid
D01308 Halcinonide
Drug classes [BR:br08332]
Anti-inflammatory
DG01955 Corticosteroid
D01308 Halcinonide
Target-based classification of drugs [BR:br08310]
Nuclear receptors
Estrogen like receptors
3-Ketosteroid receptor
NR3C1 (GR)
D01308 Halcinonide (JAN/USP/INN) <US>
Topical steroids potency [br08317.html]
Classification in the USA
D01308
|
|---|
| Other DBs |
|
|---|
| LinkDB |
|
|---|
| KCF data |
ATOM 31
1 C1x C 18.9000 -29.3300
2 C5x C 18.9000 -30.7300
3 C2x C 20.0900 -31.4300
4 C2y C 21.2800 -30.7300
5 C1z C 21.2800 -29.3300
6 C1x C 20.0900 -28.7000
7 C1x C 22.4700 -31.4300
8 C1x C 23.7300 -30.7300
9 C1y C 23.7300 -29.3300
10 C1z C 22.4700 -28.7000
11 C1y C 24.9200 -28.7000
12 C1z C 24.9200 -27.3000
13 C1x C 23.7300 -26.6000
14 C1y C 22.4700 -27.3000
15 C1a C 21.2800 -28.0000
16 O1a O 21.2800 -26.6000
17 C1a C 24.9200 -25.9000
18 X F 22.4700 -30.0300
19 O5x O 17.7100 -31.4300
20 C1x C 27.3449 -28.7000
21 C1y C 27.3449 -27.3000
22 C1z C 26.1324 -26.6000
23 C5a C 26.1324 -25.0602
24 C1b C 24.9032 -24.3503
25 O5a O 27.3280 -24.3698
26 X Cl 23.6992 -25.0454
27 O2x O 27.3279 -25.9096
28 O2x O 28.6704 -26.7814
29 C1z C 28.7279 -25.9096
30 C1a C 28.7279 -24.5096
31 C1a C 30.1279 -25.9096
BOND 35
1 1 2 1
2 2 3 1
3 3 4 2
4 4 5 1
5 5 6 1
6 1 6 1
7 4 7 1
8 7 8 1
9 8 9 1
10 9 10 1
11 5 10 1
12 9 11 1
13 11 12 1
14 12 13 1
15 13 14 1
16 10 14 1
17 5 15 1 #Up
18 14 16 1 #Up
19 12 17 1 #Up
20 10 18 1 #Down
21 2 19 2
22 11 20 1
23 20 21 1
24 21 22 1
25 12 22 1
26 22 23 1 #Up
27 23 24 1
28 23 25 2
29 24 26 1
30 22 27 1 #Down
31 21 28 1 #Down
32 27 29 1
33 29 28 1
34 29 30 1
35 29 31 1
|
|---|
