| Entry |
|
|---|
| Name |
Dimethindene maleate (USAN);
Dimetindene maleate (JAN);
Forhistal maleate (TN) |
|---|
| Formula |
C20H24N2. C4H4O4
|
|---|
| Exact mass |
408.2049
|
|---|
| Mol weight |
408.49
|
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| Structure |
|
|---|
| Class |
Anti-allergic agent
DG01557 Histamine receptor antagonist
DG01482 Histamine receptor H1 antagonist
|
|---|
| Remark |
|
|---|
| Efficacy |
Antiallergic, H1 receptor antagonist |
|---|
| Target |
|
|---|
| Pathway |
| hsa04080 | Neuroactive ligand-receptor interaction |
|
|---|
| Interaction |
|
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| Brite |
Anatomical Therapeutic Chemical (ATC) classification [BR:br08303]
D DERMATOLOGICALS
D04 ANTIPRURITICS, INCL. ANTIHISTAMINES, ANESTHETICS, ETC.
D04A ANTIPRURITICS, INCL. ANTIHISTAMINES, ANESTHETICS, ETC.
D04AA Antihistamines for topical use
D04AA13 Dimetindene
D01343 Dimethindene maleate (USAN)
R RESPIRATORY SYSTEM
R06 ANTIHISTAMINES FOR SYSTEMIC USE
R06A ANTIHISTAMINES FOR SYSTEMIC USE
R06AB Substituted alkylamines
R06AB03 Dimetindene
D01343 Dimethindene maleate (USAN)
Drug groups [BR:br08330]
Anti-allergic agent
DG01557 Histamine receptor antagonist
DG01482 Histamine receptor H1 antagonist
DG00386 Dimetindene
D01343 Dimethindene maleate
Target-based classification of drugs [BR:br08310]
G Protein-coupled receptors
Rhodopsin family
Histamine
HRH1
D01343 Dimethindene maleate (USAN)
Drug groups [BR:br08330]
Anti-allergic agent
DG01557 Histamine receptor antagonist
DG01482 Histamine receptor H1 antagonist
DG00386 Dimetindene
|
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| Other DBs |
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| LinkDB |
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| KCF data |
ATOM 30
1 C8x C 20.8688 -16.1854
2 C8x C 20.8688 -17.5844
3 C8x C 22.0834 -18.2840
4 C8x C 22.0834 -15.4859
5 C8y C 23.2908 -16.1854
6 C8y C 23.2848 -17.5878
7 C1x C 24.6169 -18.0269
8 C2y C 25.4458 -16.8956
9 C2y C 24.6264 -15.7575
10 C1b C 26.8449 -16.9014
11 C1b C 27.5393 -18.1159
12 N1c N 28.9383 -18.1217
13 C1a C 29.6330 -19.3362
14 C1a C 29.6430 -16.9131
15 C1c C 24.6137 -14.3553
16 C8y C 25.8191 -13.6449
17 C1a C 23.3959 -13.6668
18 C8x C 27.0316 -14.3356
19 C8x C 28.2368 -13.6252
20 C8x C 28.2242 -12.2262
21 C8x C 27.0063 -11.5377
22 N5x N 25.8011 -12.2481
23 C6a C 38.0303 -15.9960
24 C2b C 37.3506 -14.8187
25 O6a O 37.3564 -17.1788
26 O6a O 39.3971 -16.0600
27 C2b C 35.7114 -14.8245
28 C6a C 35.0375 -16.0075
29 O6a O 33.6707 -16.0075
30 O6a O 35.7231 -17.1846
BOND 31
1 12 14 1
2 2 3 1
3 9 15 1
4 3 6 2
5 15 16 1
6 5 6 1
7 15 17 1
8 6 7 1
9 7 8 1
10 8 9 2
11 9 5 1
12 5 4 2
13 16 18 2
14 18 19 1
15 19 20 2
16 20 21 1
17 21 22 2
18 22 16 1
19 8 10 1
20 4 1 1
21 10 11 1
22 11 12 1
23 12 13 1
24 1 2 2
25 23 24 1
26 23 25 1
27 23 26 2
28 24 27 2
29 27 28 1
30 28 29 1
31 28 30 2
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