| Entry |
|
|---|
| Name |
Tolciclate (JAN/USAN/INN)
|
|---|
| Formula |
C20H21NOS
|
|---|
| Exact mass |
323.1344
|
|---|
| Mol weight |
323.4518
|
|---|
| Structure |
   |
|---|
| Simcomp |
 |
|---|
| Remark |
|
|---|
| Efficacy |
Antifungal, Ergosterol biosynthesis inhibitor |
|---|
| Comment |
Thiocarbamete
|
|---|
| Target |
squalene epoxidase [KO: K00511] |
|---|
| Pathway |
|
|---|
| Brite |
Anatomical Therapeutic Chemical (ATC) classification [BR:br08303]
D DERMATOLOGICALS
D01 ANTIFUNGALS FOR DERMATOLOGICAL USE
D01A ANTIFUNGALS FOR TOPICAL USE
D01AE Other antifungals for topical use
D01AE19 Tolciclate
D01384 Tolciclate (JAN/USAN/INN)
Risk category of Japanese OTC drugs [BR:br08312]
Second-class OTC drugs
Inorganic and organic chemicals
Tolciclate
D01384 Tolciclate (JAN/USAN/INN)
Rx-to-OTC switch list in Japan [br08314.html]
D01384
 |
|---|
| Other DBs |
|
|---|
| LinkDB |
 |
|---|
| KCF data |
ATOM 23
1 C1y C 30.3584 -15.8468
2 C1x C 29.9009 -17.2607
3 C8x C 19.5310 -16.5634
4 C8y C 19.5310 -17.9523
5 C8x C 20.7367 -18.6467
6 C8y C 21.9353 -17.9523
7 C8x C 21.9353 -16.5634
8 C8x C 20.7367 -15.8690
9 N1c N 23.1387 -18.6457
10 C1a C 23.1397 -20.0346
11 C2c C 24.3408 -17.9504
12 O2a O 25.5442 -18.6440
13 S0 S 24.3398 -16.5616
14 C8y C 26.7465 -17.9486
15 C8x C 27.9440 -18.6447
16 C8x C 27.9420 -15.8670
17 C8x C 26.7396 -16.5622
18 C8y C 29.1403 -16.5558
19 C8y C 29.1453 -17.9654
20 C1y C 30.3684 -18.6659
21 C1x C 31.5865 -17.9568
22 C1x C 31.5816 -16.5472
23 C1a C 18.3285 -18.6472
BOND 26
1 11 12 1
2 5 6 2
3 11 13 2
4 6 7 1
5 12 14 1
6 7 8 2
7 8 3 1
8 1 2 1
9 14 15 2
10 15 19 1
11 18 16 1
12 16 17 2
13 17 14 1
14 6 9 1
15 9 10 1
16 3 4 2
17 9 11 1
18 18 19 2
19 19 20 1
20 20 21 1
21 21 22 1
22 22 1 1
23 1 18 1
24 2 20 1
25 4 5 1
26 4 23 1
|
|---|
