KEGG   DRUG: Cefpirome sulfate
Entry
D01401                      Drug                                   
Name
Cefpirome sulfate (JP18/USAN);
Cefrom (TN)
Formula
C22H22N6O5S2. H2SO4
Exact mass
612.0767
Mol weight
612.66
Structure
Simcomp
Class
Antibacterial
 DG01710  beta-Lactam antibiotic
  DG01714  Cephalosporin skeleton group
   DG01488  Cephem
 DG01777  Fourth-generation cephalosporin
 DG01804  Oxyimino beta-lactam
Remark
ATC code: J01DE02
Chemical structure group: DG00587
Efficacy
Antibacterial, Cell wall biosynthesis inhibitor
Target
penicillin binding protein
  Pathway
ko00550  Peptidoglycan biosynthesis
Interaction
Brite
Anatomical Therapeutic Chemical (ATC) classification [BR:br08303]
 J ANTIINFECTIVES FOR SYSTEMIC USE
  J01 ANTIBACTERIALS FOR SYSTEMIC USE
   J01D OTHER BETA-LACTAM ANTIBACTERIALS
    J01DE Fourth-generation cephalosporins
     J01DE02 Cefpirome
      D01401  Cefpirome sulfate (JP18/USAN)
Drug groups [BR:br08330]
 Antibacterial
  DG01710  beta-Lactam antibiotic
   DG01714  Cephalosporin skeleton group
    DG01488  Cephem
     DG00587  Cefpirome
      D01401  Cefpirome sulfate
  DG01777  Fourth-generation cephalosporin
   DG00587  Cefpirome
    D01401  Cefpirome sulfate
  DG01804  Oxyimino beta-lactam
   DG00587  Cefpirome
    D01401  Cefpirome sulfate
Antimicrobials [BR:br08307]
 Antibacterials
  Cell wall biosynthesis inhibitor, beta-lactam
   Fourth-generation cephalosporin
    D01401  Cefpirome sulfate (JP18/USAN)
Drugs listed in the Japanese Pharmacopoeia [BR:br08311]
 Chemicals
  D01401  Cefpirome sulfate
Drug groups [BR:br08330]
 Antibacterial
  DG01710  beta-Lactam antibiotic
   DG01714  Cephalosporin skeleton group
    DG01488  Cephem
     DG00587  Cefpirome
  DG01777  Fourth-generation cephalosporin
   DG00587  Cefpirome
  DG01804  Oxyimino beta-lactam
   DG00587  Cefpirome
Antimicrobials abbreviations [BR:br08327]
 Antibacterials
  Cell wall biosynthesis inhibitor, beta-lactam
   Fourth-generation cephalosporin
    DG00587  Cefpirome
Other DBs
CAS: 98753-19-6
PubChem: 7848464
ChEBI: 31378
LigandBox: D01401
NIKKAJI: J550.746D
LinkDB
KCF data

ATOM        40
            1   S4a S    27.3857  -19.1255
            2   O1d O    27.3857  -17.7147
            3   O1d O    25.9850  -19.1119
            4   O1d O    28.7859  -19.1188
            5   O1d O    27.4483  -20.5193
            6   C1y C    17.4457  -16.0660
            7   N1y N    17.4457  -17.4638
            8   C2y C    18.6338  -18.1627
            9   C2y C    19.8221  -17.4638
            10  C1x C    19.8221  -16.0660
            11  S2x S    18.6338  -15.3671
            12  C1y C    16.0477  -16.0660
            13  C5x C    16.0477  -17.4638
            14  N1b N    14.7898  -15.3671
            15  C5a C    13.6017  -16.0660
            16  O5a O    13.6017  -17.4638
            17  O5x O    14.7898  -18.1627
            18  C2c C    12.4134  -15.3671
            19  C1b C    21.0801  -18.1627
            20  C8y C    11.1554  -16.0660
            21  N5y N    22.2683  -17.4638 #+
            22  C8x C    10.1070  -15.2272
            23  S2x S     8.9189  -15.9961
            24  C8y C     9.3383  -17.3938
            25  N5x N    10.7360  -17.3938
            26  N2b N    12.4134  -13.9691
            27  C6a C    18.6338  -19.5606
            28  O6a O    19.8221  -20.2596 #-
            29  O6a O    17.3758  -20.2596
            30  N1a N     8.4996  -18.5121
            31  C8x C    23.4829  -18.1651
            32  C8x C    24.6975  -17.4638
            33  C8x C    24.6975  -16.0613
            34  C8y C    23.4829  -15.3600
            35  C8y C    22.2683  -16.0613
            36  C1x C    23.1912  -13.9882
            37  C1x C    21.7964  -13.8416
            38  C1x C    21.2260  -15.1228
            39  O2a O    13.5930  -13.2945
            40  C1a C    13.5930  -11.8953
BOND        43
            1     1   2 2
            2     1   3 1
            3     1   4 1
            4     1   5 2
            5     6   7 1
            6     7   8 1
            7     8   9 2
            8     9  10 1
            9    10  11 1
            10    6  11 1
            11    6  12 1
            12   12  13 1
            13    7  13 1
            14   12  14 1 #Up
            15   14  15 1
            16   15  16 2
            17   13  17 2
            18   15  18 1
            19    9  19 1
            20   18  20 1
            21   19  21 1
            22   20  22 2
            23   22  23 1
            24   23  24 1
            25   24  25 2
            26   20  25 1
            27   18  26 2
            28    8  27 1
            29   27  28 1
            30   27  29 2
            31   24  30 1
            32   21  31 2
            33   31  32 1
            34   32  33 2
            35   33  34 1
            36   34  35 2
            37   21  35 1
            38   34  36 1
            39   36  37 1
            40   37  38 1
            41   35  38 1
            42   26  39 1
            43   39  40 1

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