KEGG   DRUG: Sobuzoxane
Entry
D01404                      Drug                                   
Name
Sobuzoxane (JAN);
Perazolin (TN)
Formula
C22H34N4O10
Exact mass
514.2275
Mol weight
514.5262
Structure
Class
Antineoplastic
 DG01529  Topoisomerase inhibitor
  DG01527  Topoisomerase II inhibitor
Remark
Therapeutic category: 4291
Product: D01404<JP>
Efficacy
Antineoplastic, Topoisomerase II inhibitor
Target
TOP2 [HSA:7153 7155] [KO:K03164]
Interaction
Brite
Therapeutic category of drugs in Japan [BR:br08301]
 4  Agents affecting cellular function
  42  Antineoplastics
   429  Miscellaneous
    4291  Other Antitumors
     D01404  Sobuzoxane (JAN)
Drug groups [BR:br08330]
 Antineoplastic
  DG01529  Topoisomerase inhibitor
   DG01527  Topoisomerase II inhibitor
    D01404  Sobuzoxane
Target-based classification of drugs [BR:br08310]
 Enzymes
  Isomerases (EC5)
   DNA topoisomerase
    TOP2
     D01404  Sobuzoxane (JAN) <JP>
Other DBs
CAS: 98631-95-9
PubChem: 7848467
ChEBI: 32136
LigandBox: D01404
NIKKAJI: J269.578B
LinkDB
KCF data

ATOM        36
            1   N1y N    25.1657  -18.4716
            2   C1x C    23.9502  -17.7720
            3   C5x C    22.7365  -18.4748
            4   N1y N    22.7383  -19.8773
            5   C5x C    23.9539  -20.5769
            6   C1x C    25.1676  -19.8741
            7   C5x C    30.0347  -15.7156
            8   C1x C    28.7422  -16.4081
            9   N1y N    28.8042  -17.8141
            10  C1x C    30.0187  -18.5274
            11  C5x C    31.2412  -17.8278
            12  N1y N    31.2492  -16.4220
            13  C1b C    32.4587  -15.7156
            14  O7a O    33.6740  -16.4081
            15  C7a C    34.8825  -15.7084
            16  O7a O    36.0980  -16.4009
            17  C1b C    37.3136  -15.7013
            18  O6a O    34.8755  -14.3021
            19  C1c C    38.5332  -16.3996
            20  C1a C    39.7511  -15.6984
            21  C1a C    38.5220  -17.7932
            22  O5x O    30.0276  -14.3163
            23  C1b C    27.5826  -18.4928
            24  C1b C    26.3811  -17.7861
            25  C1b C    21.5263  -20.5705
            26  O7a O    20.3179  -19.8778
            27  C7a C    19.1094  -20.5774
            28  O7a O    17.9010  -19.8849
            29  C1b C    16.6926  -20.5845
            30  C1c C    15.4842  -19.8921
            31  O6a O    19.1025  -21.9767
            32  C1a C    15.4772  -18.4928
            33  C1a C    14.2754  -20.5966
            34  O5x O    21.5193  -17.7720
            35  O5x O    23.9430  -21.9697
            36  O5x O    32.4444  -18.5210
BOND        37
            1    11  12 1
            2    15  18 2
            3    12   7 1
            4    17  19 1
            5    19  20 1
            6    19  21 1
            7     1   2 1
            8     7  22 2
            9     2   3 1
            10    9  23 1
            11    3   4 1
            12   23  24 1
            13   24   1 1
            14    4   5 1
            15    4  25 1
            16    5   6 1
            17   25  26 1
            18    6   1 1
            19   26  27 1
            20   12  13 1
            21   27  28 1
            22    7   8 1
            23   28  29 1
            24   13  14 1
            25   29  30 1
            26    8   9 1
            27   27  31 2
            28   14  15 1
            29   30  32 1
            30    9  10 1
            31   30  33 1
            32   15  16 1
            33    3  34 2
            34   10  11 1
            35    5  35 2
            36   16  17 1
            37   11  36 2

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