| Entry |
|
|---|
| Name |
Talipexole hydrochloride (JAN);
Domin (TN) |
|---|
| Formula |
C10H15N3S. 2HCl
|
|---|
| Exact mass |
281.0520
|
|---|
| Mol weight |
282.23
|
|---|
| Structure |
|
|---|
| Simcomp |
|
|---|
| Class |
Neuropsychiatric agent
DG01472 Dopamine agonist
DG01468 Dopamine D2-receptor agonist
|
|---|
| Remark |
|
|---|
| Efficacy |
Antiparkinsonian, Dopamine D2 receptor agonist |
|---|
| Target |
|
|---|
| Pathway |
| hsa04080 | Neuroactive ligand-receptor interaction |
|
|---|
| Interaction |
|
|---|
| Structure map |
| map07213 | Dopamine receptor agonists/antagonists |
|
|---|
| Brite |
Drug groups [BR:br08330]
Neuropsychiatric agent
DG01472 Dopamine agonist
DG01468 Dopamine D2-receptor agonist
DG01326 Talipexole
D01505 Talipexole hydrochloride
Target-based classification of drugs [BR:br08310]
G Protein-coupled receptors
Rhodopsin family
Dopamine
DRD2
D01505 Talipexole hydrochloride (JAN)
Drug groups [BR:br08330]
Neuropsychiatric agent
DG01472 Dopamine agonist
DG01468 Dopamine D2-receptor agonist
DG01326 Talipexole
|
|---|
| Other DBs |
|
|---|
| LinkDB |
|
|---|
| KCF data |
ATOM 16
1 X Cl 21.5600 -24.8500
2 C8y C 13.5800 -24.0800
3 C8y C 13.5800 -25.4800
4 N5x N 14.9100 -25.9000
5 C8y C 15.7500 -24.7800
6 S2x S 14.9100 -23.6600
7 C1x C 12.4600 -23.1700
8 C1x C 11.1300 -23.5200
9 N1y N 10.5000 -24.7800
10 C1x C 11.1300 -26.0400
11 C1x C 12.4600 -26.3200
12 C1b C 9.1000 -24.7800
13 N1a N 17.1500 -24.7800
14 C2b C 8.4000 -23.5676
15 C2a C 7.0002 -23.5676
16 X Cl 21.5600 -24.8500
BOND 15
1 2 3 2
2 3 4 1
3 4 5 2
4 5 6 1
5 2 6 1
6 8 9 1
7 9 10 1
8 7 8 1
9 3 11 1
10 2 7 1
11 10 11 1
12 9 12 1
13 5 13 1
14 12 14 1
15 14 15 2
BRACKET 1 19.8100 -25.7600 19.8100 -23.8700
1 22.4000 -23.8700 22.4000 -25.7600
1 2
ORIGINAL 1 1
REPEAT 1 16
|
|---|
