| Entry |
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| Name |
Flufenamic acid (JAN/USAN/INN);
Arlef (TN) |
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| Formula |
C14H10F3NO2
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| Exact mass |
281.0664
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| Mol weight |
281.23
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| Structure |
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| Simcomp |
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| Class |
Anti-inflammatory
DG01504 Nonsteroidal anti-inflammatory drug (NSAID)
DG01911 Anti-inflammatory drug, fenamic acid derivatives
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| Remark |
| Product (DG00757): | D01823<JP> |
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| Efficacy |
Anti-inflammatory, COX inhibitor |
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| Comment |
Fenamic acid derivative
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| Target |
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| Pathway |
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| Interaction |
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| Structure map |
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| Brite |
Anatomical Therapeutic Chemical (ATC) classification [BR:br08303]
M MUSCULO-SKELETAL SYSTEM
M01 ANTIINFLAMMATORY AND ANTIRHEUMATIC PRODUCTS
M01A ANTIINFLAMMATORY AND ANTIRHEUMATIC PRODUCTS, NON-STEROIDS
M01AG Fenamates
M01AG03 Flufenamic acid
D01581 Flufenamic acid (JAN/USAN/INN)
Drug groups [BR:br08330]
Anti-inflammatory
DG01504 Nonsteroidal anti-inflammatory drug (NSAID)
DG01911 Anti-inflammatory drug, fenamic acid derivatives
DG00757 Flufenamic acid
D01581 Flufenamic acid
Target-based classification of drugs [BR:br08310]
Enzymes
Oxidoreductases (EC1)
Prostaglandin synthase
PTGS1 (COX1)
D01581 Flufenamic acid (JAN/USAN/INN)
PTGS2 (COX2)
D01581 Flufenamic acid (JAN/USAN/INN)
Drug groups [BR:br08330]
Anti-inflammatory
DG01504 Nonsteroidal anti-inflammatory drug (NSAID)
DG01911 Anti-inflammatory drug, fenamic acid derivatives
DG00757 Flufenamic acid
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| Other DBs |
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| LinkDB |
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| KCF data |
ATOM 20
1 C8x C 18.0229 -18.1131
2 C8x C 18.0229 -19.5137
3 C8x C 19.2388 -20.2140
4 C8x C 20.4475 -19.5137
5 C8y C 20.4475 -18.1131
6 C8y C 19.2388 -17.4128
7 N1b N 21.6611 -17.4137
8 C8y C 22.8735 -18.1148
9 C8x C 22.8670 -19.5136
10 C8x C 24.0794 -20.2147
11 C8x C 25.2929 -19.5153
12 C8y C 25.2939 -18.1146
13 C8x C 24.0814 -17.4135
14 C6a C 19.2405 -16.0122
15 O6a O 20.4543 -15.3134
16 O6a O 18.0285 -15.3104
17 C1d C 26.5013 -17.4187
18 X F 27.7238 -16.7323
19 X F 25.8102 -16.2189
20 X F 27.2104 -18.6459
BOND 21
1 5 6 1
2 6 1 2
3 8 9 1
4 9 10 2
5 10 11 1
6 11 12 2
7 12 13 1
8 13 8 2
9 5 7 1
10 1 2 1
11 7 8 1
12 6 14 1
13 2 3 2
14 14 15 1
15 3 4 1
16 14 16 2
17 4 5 2
18 12 17 1
19 17 18 1
20 17 19 1
21 17 20 1
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