| Entry |
|
|---|
| Name |
Loteprednol etabonate (JAN/USAN);
Lotemax (TN) |
|---|
| Product |
|
|---|
| Generic |
LOTEPREDNOL ETABONATE (ARMAS PHARMACEUTICALS), LOTEPREDNOL ETABONATE (ARMAS PHARMACEUTICALS), LOTEPREDNOL ETABONATE (ARMAS PHARMACEUTICALS), LOTEPREDNOL ETABONATE (Amneal Pharmaceuticals NY LLC), LOTEPREDNOL ETABONATE (Amneal Pharmaceuticals NY LLC), LOTEPREDNOL ETABONATE (Bausch & Lomb Americas), LOTEPREDNOL ETABONATE (Bausch & Lomb Americas), LOTEPREDNOL ETABONATE (Bausch & Lomb Incorporated), LOTEPREDNOL ETABONATE (Bryant Ranch Prepack), LOTEPREDNOL ETABONATE (Lupin Pharmaceuticals), LOTEPREDNOL ETABONATE (NorthStar RxLLC), LOTEPREDNOL ETABONATE (Oceanside Pharmaceuticals), LOTEPREDNOL ETABONATE (Padagis US LLC), LOTEPREDNOL ETABONATE (Padagis US LLC), LOTEPREDNOL ETABONATE (Sun Pharmaceutical Industries) |
|---|
| Formula |
C24H31ClO7
|
|---|
| Exact mass |
466.1758
|
|---|
| Mol weight |
466.95
|
|---|
| Structure |
|
|---|
| Simcomp |
|
|---|
| Class |
|
|---|
| Remark |
| Product (DG01127): | D01689<US> |
| Product (mixture): | D12133<US> |
|
|---|
| Efficacy |
Anti-inflammatory (topical), Glucocorticoid receptor agonist |
|---|
| Target |
|
|---|
| Pathway |
| hsa04080 | Neuroactive ligand-receptor interaction |
|
|---|
| Interaction |
|
|---|
| Brite |
Anatomical Therapeutic Chemical (ATC) classification [BR:br08303]
S SENSORY ORGANS
S01 OPHTHALMOLOGICALS
S01B ANTIINFLAMMATORY AGENTS
S01BA Corticosteroids, plain
S01BA14 Loteprednol
D01689 Loteprednol etabonate (JAN/USAN) <US>
USP drug classification [BR:br08302]
Ophthalmic Agents
Ophthalmic Anti-inflammatories
Glucocorticoids, Ophthalmic
Loteprednol
D01689 Loteprednol etabonate (JAN/USAN)
Drug groups [BR:br08330]
Anti-inflammatory
DG01955 Corticosteroid
DG02068 Glucocorticoid
DG01127 Loteprednol
D01689 Loteprednol etabonate
Drug classes [BR:br08332]
Anti-inflammatory
DG01955 Corticosteroid
D01689 Loteprednol etabonate
Target-based classification of drugs [BR:br08310]
Nuclear receptors
Estrogen like receptors
3-Ketosteroid receptor
NR3C1 (GR)
D01689 Loteprednol etabonate (JAN/USAN) <US>
Drug groups [BR:br08330]
Anti-inflammatory
DG01955 Corticosteroid
DG02068 Glucocorticoid
DG01127 Loteprednol
|
|---|
| Other DBs |
|
|---|
| LinkDB |
|
|---|
| KCF data |
ATOM 32
1 C1z C 27.1943 -18.2248
2 C1z C 26.0075 -18.8849
3 C1x C 28.3695 -18.9200
4 C7a C 27.2177 -16.8387
5 O7a O 28.3870 -17.5164
6 C1y C 26.0308 -20.2998
7 C1x C 24.8204 -18.2014
8 C1a C 25.9958 -17.4932
9 C1x C 28.3518 -20.2883
10 O7a O 26.0307 -16.1247
11 O6a O 28.4279 -16.1598
12 C7a C 29.7671 -17.5164
13 C1y C 24.7970 -20.9263
14 C1y C 23.5855 -18.8615
15 C1b C 24.8263 -16.8153
16 O7a O 30.4519 -16.3236
17 O6a O 30.4636 -18.7151
18 C1y C 23.6205 -20.2356
19 C1x C 24.7970 -22.2888
20 O1a O 22.4455 -18.1897
21 X Cl 23.6205 -16.1189
22 C1b C 31.8319 -16.3236
23 C1z C 22.4338 -20.9146
24 C1x C 23.6088 -22.9665
25 C2y C 22.4279 -22.2829
26 C2x C 21.2528 -20.2296
27 C1a C 22.4221 -19.5461
28 C2x C 21.2528 -22.9606
29 C2x C 20.0773 -20.9146
30 C5x C 20.0773 -22.2829
31 O5x O 18.8906 -22.9547
32 C1a C 32.5249 -15.1180
BOND 35
1 1 5 1 #Down
2 2 6 1
3 2 7 1
4 2 8 1 #Up
5 3 9 1
6 4 10 1
7 4 11 2
8 5 12 1
9 6 13 1
10 7 14 1
11 10 15 1
12 12 16 1
13 12 17 2
14 13 18 1
15 13 19 1
16 14 20 1 #Up
17 15 21 1
18 16 22 1
19 18 23 1
20 19 24 1
21 23 25 1
22 23 26 1
23 23 27 1 #Up
24 25 28 2
25 26 29 2
26 28 30 1
27 30 31 2
28 6 9 1
29 14 18 1
30 24 25 1
31 29 30 1
32 22 32 1
33 1 2 1
34 1 3 1
35 1 4 1 #Up
|
|---|
