KEGG   DRUG: Amorolfine hydrochlorideHelp
Entry
D01720                      Drug                                   

Name
Amorolfine hydrochloride (JAN);
Pekiron (TN)
Formula
C21H35NO. HCl
Exact mass
353.2485
Mol weight
353.9696
Structure
Mol fileKCF fileDB search
Simcomp SIMCOMP
Remark
Therapeutic category: 2659
ATC code: D01AE16
Chemical structure group: DG00376
Product (DG00376): D01720<JP>
Efficacy
Antifungal, Ergosterol biosynthesis inhibitor
Comment
Morpholine derivative
Target
squalene epoxidase [KO:K00511]
  Pathway
ko00100  Steroid biosynthesis
Structure map
map07026  Antifungal agents
Brite
Anatomical Therapeutic Chemical (ATC) classification [BR:br08303]
 D DERMATOLOGICALS
  D01 ANTIFUNGALS FOR DERMATOLOGICAL USE
   D01A ANTIFUNGALS FOR TOPICAL USE
    D01AE Other antifungals for topical use
     D01AE16 Amorolfine
      D01720  Amorolfine hydrochloride (JAN) <JP>
Therapeutic category of drugs in Japan [BR:br08301]
 2  Agents affecting individual organs
  26  Epidermides
   265  Antiparasitic dermatosis agents
    2659  Others
     D01720  Amorolfine hydrochloride (JAN)
Classification of Japanese OTC drugs [BR:br08313]
 Agents for integumentary system
  58 Ringworm drugs
   D01720  Amorolfine hydrochloride (JAN)
Risk category of Japanese OTC drugs [BR:br08312]
 Designated second-class OTC drugs
  Inorganic and organic chemicals
   Amorolfine
    D01720  Amorolfine hydrochloride (JAN)
 Second-class OTC drugs
  Inorganic and organic chemicals
   Amorolfine
    D01720  Amorolfine hydrochloride (JAN)
Antiinfectives [br08350.html]
 Antifungals
  D01720
Rx-to-OTC switch list in Japan [br08314.html]
 D01720
BRITE hierarchy
Other DBs
CAS: 78613-38-4
PubChem: 7848783
ChEBI: 59649 599440
LigandBox: D01720
NIKKAJI: J578.630D
LinkDB All DBs
KCF data Show

ATOM        24
            1   C8y C    17.0998  -17.3199
            2   C8x C    17.0998  -18.7218
            3   C8x C    18.3179  -19.4261
            4   C8y C    19.5288  -18.7218
            5   C8x C    19.5288  -17.3199
            6   C8x C    18.3179  -16.6224
            7   C1b C    20.7349  -19.4192
            8   C1c C    21.9395  -18.7147
            9   C1b C    23.1512  -19.4121
            10  N1y N    24.3630  -18.7076
            11  C1x C    25.5745  -19.4050
            12  C1y C    26.7863  -18.7006
            13  C1a C    21.9365  -17.3127
            14  C1x C    24.3599  -17.3057
            15  C1y C    25.5733  -16.6057
            16  O2x O    26.7899  -17.3003
            17  C1d C    15.8812  -16.6224
            18  C1b C    15.8793  -15.2204
            19  C1a C    14.6670  -17.3214
            20  C1a C    16.8733  -15.6277
            21  C1a C    14.6633  -14.5176
            22  C1a C    25.5702  -15.2033
            23  C1a C    27.9767  -19.3880
            24  X   Cl   29.9321  -17.1918
BOND        24
            1     4   5 1
            2    11  12 1
            3     5   6 2
            4     6   1 1
            5     8  13 1
            6    10  14 1
            7     4   7 1
            8    14  15 1
            9    12  16 1
            10    7   8 1
            11   15  16 1
            12    1   2 2
            13    1  17 1
            14    8   9 1
            15   17  18 1
            16    2   3 1
            17   17  19 1
            18    9  10 1
            19   17  20 1
            20    3   4 2
            21   18  21 1
            22   10  11 1
            23   15  22 1 #Down
            24   12  23 1 #Down

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