| Entry |
|
|---|
| Name |
Sorivudine (JAN/USAN/INN);
Bravavir (TN) |
|---|
| Formula |
C11H13BrN2O6
|
|---|
| Exact mass |
347.9957
|
|---|
| Mol weight |
349.13
|
|---|
| Structure |
|
|---|
| Simcomp |
|
|---|
| Class |
Antiviral
DG01890 Nucleoside reverse transcriptase inhibitor (NRTI)
DG03346 Zidovudine type antiviral
|
|---|
| Efficacy |
Antiviral, DNA polymerase inhibitor |
|---|
| Comment |
Thymidine derivative
Zidovudine type
|
|---|
| Target |
Herpesvirus DNA polymerase [KO: K18964] |
|---|
| Pathway |
|
|---|
| Structure map |
|
|---|
| Brite |
Drug groups [BR:br08330]
Antiviral
DG01890 Nucleoside reverse transcriptase inhibitor (NRTI)
DG03346 Zidovudine type antiviral
D01734 Sorivudine
Antimicrobials [BR:br08307]
Antivirals
Genome replication inhibitor
Herpesvirus DNA polymerase inhibitor
D01734 Sorivudine (JAN/USAN/INN)
|
|---|
| Other DBs |
|
|---|
| LinkDB |
|
|---|
| KCF data |
ATOM 20
1 N4y N 25.5500 -16.3800
2 C8y C 26.7400 -15.6800
3 C8x C 24.2900 -15.6800
4 N4x N 26.7400 -14.2800
5 O5x O 27.9300 -16.3800
6 C8y C 24.2900 -14.2800
7 C8y C 25.5500 -13.5800
8 O5x O 25.5500 -12.1800
9 C1y C 23.9400 -17.2900
10 C1y C 21.7000 -17.2900
11 C1y C 22.1200 -18.6200
12 C1y C 23.5200 -18.6200
13 O2x O 22.8200 -16.4500
14 O1a O 24.3476 -19.7492
15 C1b C 20.3670 -16.8620
16 O1a O 21.2924 -19.7492
17 O1a O 19.3275 -17.8045
18 C2b C 23.0834 -13.5700
19 C2b C 21.8737 -14.2553
20 X Br 20.6534 -13.5370
BOND 21
1 1 2 1
2 1 3 1
3 2 4 1
4 2 5 2
5 3 6 2
6 4 7 1
7 7 8 2
8 6 7 1
9 9 1 1 #Up
10 10 11 1
11 11 12 1
12 12 9 1
13 9 13 1
14 10 13 1
15 12 14 1 #Up
16 10 15 1 #Up
17 11 16 1 #Down
18 15 17 1
19 6 18 1
20 18 19 2
21 19 20 1
|
|---|
