| Entry |
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| Name |
Thonzylamine hydrochloride (JAN/USAN);
Super anahist (TN) |
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| Formula |
C16H22N4O. HCl
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| Exact mass |
322.1560
|
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| Mol weight |
322.83
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| Structure |
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| Simcomp |
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| Class |
Anti-allergic agent
DG01557 Histamine receptor antagonist
DG01482 Histamine receptor H1 antagonist
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| Remark |
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| Efficacy |
Antiallergic, H1 receptor antagonist |
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| Comment |
Phenbenzamine derivative
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| Target |
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| Pathway |
| hsa04080 | Neuroactive ligand-receptor interaction |
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| Interaction |
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| Structure map |
| map07212 | Histamine H1 receptor antagonists |
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| Brite |
Anatomical Therapeutic Chemical (ATC) classification [BR:br08303]
D DERMATOLOGICALS
D04 ANTIPRURITICS, INCL. ANTIHISTAMINES, ANESTHETICS, ETC.
D04A ANTIPRURITICS, INCL. ANTIHISTAMINES, ANESTHETICS, ETC.
D04AA Antihistamines for topical use
D04AA01 Thonzylamine
D01801 Thonzylamine hydrochloride (JAN/USAN)
R RESPIRATORY SYSTEM
R01 NASAL PREPARATIONS
R01A DECONGESTANTS AND OTHER NASAL PREPARATIONS FOR TOPICAL USE
R01AC Antiallergic agents, excl. corticosteroids
R01AC06 Thonzylamine
D01801 Thonzylamine hydrochloride (JAN/USAN)
R06 ANTIHISTAMINES FOR SYSTEMIC USE
R06A ANTIHISTAMINES FOR SYSTEMIC USE
R06AC Substituted ethylene diamines
R06AC06 Thonzylamine
D01801 Thonzylamine hydrochloride (JAN/USAN)
Risk category of Japanese OTC drugs [BR:br08312]
Second-class OTC drugs
Inorganic and organic chemicals
Thonzylamine
D01801 Thonzylamine hydrochloride (JAN/USAN)
Drug groups [BR:br08330]
Anti-allergic agent
DG01557 Histamine receptor antagonist
DG01482 Histamine receptor H1 antagonist
DG00381 Thonzylamine
D01801 Thonzylamine hydrochloride
Target-based classification of drugs [BR:br08310]
G Protein-coupled receptors
Rhodopsin family
Histamine
HRH1
D01801 Thonzylamine hydrochloride (JAN/USAN)
Drug groups [BR:br08330]
Anti-allergic agent
DG01557 Histamine receptor antagonist
DG01482 Histamine receptor H1 antagonist
DG00381 Thonzylamine
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| Other DBs |
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| LinkDB |
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| KCF data |
ATOM 22
1 X Cl 30.8063 -25.0296
2 N5x N 23.8700 -23.5900
3 C8x C 23.8700 -25.0600
4 C8x C 25.1300 -25.7600
5 C8x C 26.3200 -25.0600
6 N5x N 26.3200 -23.5900
7 C8y C 25.1300 -22.8900
8 N1c N 25.1300 -21.4900
9 C1b C 23.8700 -20.7900
10 C1b C 26.3200 -20.7900
11 C8y C 22.6800 -21.4900
12 C8x C 21.4900 -20.7900
13 C8x C 20.2300 -21.4900
14 C8y C 20.2300 -22.8900
15 C8x C 21.4200 -23.5900
16 C8x C 22.6800 -22.8900
17 O2a O 19.0400 -23.6600
18 C1a C 17.7800 -22.9600
19 C1b C 27.5100 -21.4900
20 N1c N 28.7000 -20.7900
21 C1a C 29.8900 -21.4900
22 C1a C 28.7000 -19.3900
BOND 22
1 2 3 2
2 3 4 1
3 4 5 2
4 5 6 1
5 6 7 2
6 2 7 1
7 7 8 1
8 8 9 1
9 8 10 1
10 9 11 1
11 11 12 2
12 12 13 1
13 13 14 2
14 14 15 1
15 15 16 2
16 11 16 1
17 14 17 1
18 17 18 1
19 10 19 1
20 19 20 1
21 20 21 1
22 20 22 1
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