KEGG   DRUG: Reglitazar
Entry
D01971                      Drug                                   
Name
Reglitazar (JAN/INN)
Formula
C22H20N2O5
Exact mass
392.1372
Mol weight
392.4046
Structure
Class
Antidiabetic agent
 DG01685  Insulin sensitizer
  DG01795  PPAR gamma agonist
   DG01732  Non-thiazolidinedione type PPAR agonist
Efficacy
Antidiabetic, Hypoglycemic, Peroxisome proliferator-activated receptor (PPAR) gamma agonist
Target
NR1C3 (PPARG) [HSA:5468] [KO:K08530]
  Pathway
hsa03320  PPAR signaling pathway
Interaction
Brite
Drug groups [BR:br08330]
 Antidiabetic agent
  DG01685  Insulin sensitizer
   DG01795  PPAR gamma agonist
    DG01732  Non-thiazolidinedione type PPAR agonist
     D01971  Reglitazar
Target-based classification of drugs [BR:br08310]
 Nuclear receptors
  Thyroid hormone like receptors
   Peroxisome proliferator-activated receptor (PPAR)
    NR1C3 (PPARG)
     D01971  Reglitazar (JAN/INN)
Other DBs
CAS: 170861-63-9
PubChem: 7849033
LigandBox: D01971
LinkDB
KCF data

ATOM        29
            1   O2a O    32.6340  -18.1511
            2   C8y C    33.8945  -17.4508
            3   C8x C    35.0851  -18.1511
            4   C8x C    36.3456  -17.5209
            5   C8y C    36.3456  -16.1202
            6   C8x C    35.1551  -15.3498
            7   C8x C    33.8945  -16.0501
            8   C1b C    37.5362  -15.4198
            9   C1y C    38.7968  -16.1202
            10  O2x O    27.2416  -16.1202
            11  C8y C    28.6421  -16.1202
            12  C8y C    28.9924  -17.4508
            13  N5x N    27.9419  -18.2911
            14  C8y C    26.8213  -17.4508
            15  C1b C    31.3734  -17.4508
            16  C1b C    30.1829  -18.1511
            17  C1a C    29.4125  -14.9997
            18  C8x C    23.1797  -19.4817
            19  C8x C    23.1797  -18.1511
            20  C8x C    24.3703  -17.4508
            21  C8y C    25.6309  -18.1511
            22  C8x C    25.6309  -19.4817
            23  C8x C    24.3703  -20.1820
            24  C5x C    38.7879  -17.5418
            25  N1x N    40.1362  -17.9864
            26  O7x O    40.9757  -16.8414
            27  C7x C    40.1462  -15.6893
            28  O6a O    40.5814  -14.3693
            29  O5x O    37.6329  -18.3736
BOND        32
            1     1   2 1
            2     2   3 2
            3     3   4 1
            4     4   5 2
            5     5   6 1
            6     6   7 2
            7     2   7 1
            8     5   8 1
            9     8   9 1
            10   10  11 1
            11   11  12 2
            12   12  13 1
            13   13  14 2
            14   10  14 1
            15    1  15 1
            16   15  16 1
            17   16  12 1
            18   11  17 1
            19   18  19 1
            20   19  20 2
            21   20  21 1
            22   21  22 2
            23   22  23 1
            24   18  23 2
            25   21  14 1
            26    9  24 1
            27   24  25 1
            28   25  26 1
            29   26  27 1
            30    9  27 1
            31   27  28 2
            32   24  29 2

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