DRUG: Polidocanol
Entry
D01993 Drug
Name
Polidocanol (JAN);
Asclera (TN);
Aethoxysklerol (TN);
Varithena (TN)
Product
ASCLERA (Merz North America)
Formula
C12H26O(C2H4O)n
Structure
Simcomp
Class
Cardiovascular agent
DG02016
Hemostatics
Remark
Therapeutic category:
3329
ATC code:
C05BB02
Product:
D01993<
JP
/US>
Efficacy
Antivaricose, Hemostatic, Sclerosing agent
Comment
average polymer, n=9
Interaction
Brite
Anatomical Therapeutic Chemical (ATC) classification [BR:
br08303
]
C CARDIOVASCULAR SYSTEM
C05 VASOPROTECTIVES
C05B ANTIVARICOSE THERAPY
C05BB Sclerosing agents for local injection
C05BB02 Polidocanol
D01993 Polidocanol (JAN) <JP/US>
Therapeutic category of drugs in Japan [BR:
br08301
]
3 Agents affecting metabolism
33 Blood and body fluid agents
332 Hemostatics
3329 Others
D01993 Polidocanol (JAN)
New drug approvals in the USA [
br08319.html
]
New molecular entities and new therapeutic biological products
D01993
New drug approvals in the USA, Europe and Japan [
br08328.html
]
Approval dates by FDA, EMA and PMDA
D01993
Other DBs
CAS:
3055-99-0
PubChem:
7849055
DrugBank:
DB03538
LigandBox:
D01993
NIKKAJI:
J205.362D
LinkDB
KCF data
ATOM 16
1 O1a O 22.1200 -18.5500
2 C1b C 23.7524 -17.8500
3 C1b C 24.9649 -18.5500
4 O2a O 26.1773 -17.8500
5 C1b C 27.3897 -18.5500
6 C1b C 28.6022 -17.8500
7 C1b C 29.8353 -18.5622
8 C1b C 31.0415 -17.8660
9 C1b C 32.2233 -18.5485
10 C1b C 33.4176 -17.8591
11 C1b C 34.6053 -18.5450
12 C1b C 35.7966 -17.8573
13 C1b C 36.9858 -18.5441
14 C1b C 38.1763 -17.8568
15 C1b C 39.3660 -18.5438
16 C1a C 40.5563 -17.8567
BOND 15
1 1 2 1
2 2 3 1
3 3 4 1
4 4 5 1
5 5 6 1
6 6 7 1
7 7 8 1
8 8 9 1
9 9 10 1
10 10 11 1
11 11 12 1
12 12 13 1
13 13 14 1
14 14 15 1
15 15 16 1
BRACKET 1 23.4500 -19.9500 23.4500 -16.8000
1 26.6000 -16.8000 26.6000 -19.9500
1 n
ORIGINAL 1 2 3 4
REPEAT 1
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