| Entry |
|
|---|
| Name |
Timiperone (JAN);
Tolopelon (TN) |
|---|
| Formula |
C22H24FN3OS
|
|---|
| Exact mass |
397.1624
|
|---|
| Mol weight |
397.51
|
|---|
| Structure |
|
|---|
| Simcomp |
|
|---|
| Class |
Neuropsychiatric agent
DG01478 Dopamine antagonist
DG01474 Dopamine D2-receptor antagonist
DG03200 Antipsychotic agent
DG01940 Butyrophenone derivative
|
|---|
| Remark |
| Therapeutic category: | 1179 |
|
|---|
| Efficacy |
Antipsychotic, Dopamine D2 receptor antagonist |
|---|
| Comment |
Butyropnenone derivative
|
|---|
| Target |
|
|---|
| Pathway |
| hsa04080 | Neuroactive ligand-receptor interaction |
|
|---|
| Interaction |
|
|---|
| Structure map |
| map07031 | Antipsychotics - butyrophenones |
|
|---|
| Brite |
Therapeutic category of drugs in Japan [BR:br08301]
1 Agents affecting nervous system and sensory organs
11 Agents affecting central nervous system
117 Psychotropics
1179 Others
D02035 Timiperone (JAN)
Drug groups [BR:br08330]
Neuropsychiatric agent
DG01478 Dopamine antagonist
DG01474 Dopamine D2-receptor antagonist
D02035 Timiperone
DG03200 Antipsychotic agent
DG01940 Butyrophenone derivative
D02035 Timiperone
Target-based classification of drugs [BR:br08310]
G Protein-coupled receptors
Rhodopsin family
Dopamine
DRD2
D02035 Timiperone (JAN) <JP>
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| Other DBs |
|
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| LinkDB |
|
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| KCF data |
ATOM 28
1 C8x C 24.1433 -18.9401
2 C8y C 24.1433 -20.3393
3 C8x C 25.3550 -21.0389
4 C8x C 26.5668 -20.3393
5 C8y C 26.5668 -18.9401
6 C8x C 25.3550 -18.2405
7 X F 22.9317 -21.0389
8 C5a C 27.7803 -18.2405
9 C1b C 28.9920 -18.9401
10 C1b C 30.2038 -18.2405
11 C1b C 31.4155 -18.9401
12 N1y N 32.6272 -18.2405
13 C1x C 33.8422 -18.9420
14 C1x C 35.0540 -18.2424
15 C1y C 35.0540 -16.8432
16 C1x C 33.8389 -16.1417
17 C1x C 32.6273 -16.8413
18 N4y N 36.2688 -16.1419
19 C8y C 37.6022 -16.5563
20 C8y C 38.4102 -15.4132
21 N4x N 37.5727 -14.2915
22 C8y C 36.2472 -14.7414
23 O5a O 27.7808 -16.8413
24 S0 S 35.1249 -13.9505
25 C8x C 39.8102 -15.4132
26 C8x C 40.5093 -16.6241
27 C8x C 39.8291 -17.8019
28 C8x C 38.4302 -17.8017
BOND 31
1 1 2 2
2 2 3 1
3 3 4 2
4 4 5 1
5 5 6 2
6 1 6 1
7 2 7 1
8 5 8 1
9 8 9 1
10 9 10 1
11 10 11 1
12 11 12 1
13 12 13 1
14 13 14 1
15 14 15 1
16 15 16 1
17 16 17 1
18 12 17 1
19 15 18 1
20 18 19 1
21 19 20 2
22 20 21 1
23 21 22 1
24 18 22 1
25 8 23 2
26 22 24 2
27 20 25 1
28 25 26 2
29 26 27 1
30 27 28 2
31 28 19 1
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