KEGG   DRUG: Tropisetron hydrochloride
Entry
D02041                      Drug                                   
Name
Tropisetron hydrochloride (JAN);
Navoban (TN)
Formula
C17H20N2O2. HCl
Exact mass
320.1292
Mol weight
320.81
Structure
Simcomp
Class
Gastrointestinal agent
 DG01489  5-HT3-receptor antagonist
 DG01762  Antiemetic
Remark
ATC code: A04AA03
Chemical structure group: DG00062
Efficacy
Anti-emetic, Serotonin 5-HT3 receptor antagonist
Target
  Pathway
hsa04726  Serotonergic synapse
Interaction
Structure map
map07211  Serotonin receptor agonists/antagonists
Brite
Anatomical Therapeutic Chemical (ATC) classification [BR:br08303]
 A ALIMENTARY TRACT AND METABOLISM
  A04 ANTIEMETICS AND ANTINAUSEANTS
   A04A ANTIEMETICS AND ANTINAUSEANTS
    A04AA Serotonin (5HT3) antagonists
     A04AA03 Tropisetron
      D02041  Tropisetron hydrochloride (JAN)
Drug groups [BR:br08330]
 Gastrointestinal agent
  DG01489  5-HT3-receptor antagonist
   DG00062  Tropisetron
    D02041  Tropisetron hydrochloride
  DG01762  Antiemetic
   DG00062  Tropisetron
    D02041  Tropisetron hydrochloride
Target-based classification of drugs [BR:br08310]
 Ion channels
  Ligand-gated ion channels
   Serotonin
    HTR3
     D02041  Tropisetron hydrochloride (JAN)
Drug groups [BR:br08330]
 Gastrointestinal agent
  DG01489  5-HT3-receptor antagonist
   DG00062  Tropisetron
  DG01762  Antiemetic
   DG00062  Tropisetron
Other DBs
CAS: 105826-92-4
PubChem: 7849103
ChEBI: 77570
LigandBox: D02041
NIKKAJI: J2.209.017H
LinkDB
KCF data

ATOM        22
            1   X   Cl   38.5928  -17.3129
            2   O7a O    30.1000  -18.9700
            3   C1y C    28.9800  -18.3400
            4   C1x C    28.0000  -16.8700
            5   C1x C    28.0000  -17.8500
            6   C1y C    26.5300  -16.8700
            7   C1y C    26.4600  -17.8500
            8   N1y N    25.6900  -15.8900
            9   C1x C    25.5500  -17.4300
            10  C1x C    24.9900  -18.4800
            11  C1a C    25.6900  -14.5600
            12  C7a C    31.5000  -18.9700
            13  C8y C    32.2000  -17.7100
            14  O6a O    32.2000  -20.2300
            15  C8y C    33.6000  -17.7100
            16  C8y C    33.8800  -16.3100
            17  N4x N    32.6900  -15.6100
            18  C8x C    31.6400  -16.5200
            19  C8x C    34.6500  -18.6200
            20  C8x C    35.9800  -18.2000
            21  C8x C    36.2600  -16.8700
            22  C8x C    35.2800  -15.8900
BOND        24
            1     3   5 1
            2     4   6 1
            3     5   7 1
            4     6   8 1
            5     6   9 1
            6     7  10 1
            7     7   8 1
            8     9  10 1
            9     3   2 1 #Down
            10    3   4 1
            11    8  11 1
            12    2  12 1
            13   12  13 1
            14   12  14 2
            15   13  15 1
            16   15  16 1
            17   16  17 1
            18   17  18 1
            19   13  18 2
            20   15  19 2
            21   19  20 1
            22   20  21 2
            23   21  22 1
            24   16  22 2

» Japanese version   » Back

DBGET integrated database retrieval system