| Entry |
|
|---|
| Name |
Olprinone hydrochloride hydrate (JAN);
Coretec (TN) |
|---|
| Formula |
C14H10N4O. HCl. H2O
|
|---|
| Exact mass |
304.0727
|
|---|
| Mol weight |
304.73
|
|---|
| Structure |
|
|---|
| Simcomp |
|
|---|
| Class |
Cardiovascular agent
DG01703 Cardiotonic
DG01757 Amrinone type cardiotonic
DG01507 Phosphodiesterase III inhibitor
DG01757 Amrinone type cardiotonic
|
|---|
| Remark |
| Therapeutic category: | 2119 |
| Product (DG01396): | D02042<JP> |
|
|---|
| Efficacy |
Cardiotonic, Phosphodiesterase 3 inhibitor |
|---|
| Comment |
Amrinone derivative
|
|---|
| Target |
|
|---|
| Pathway |
|
|---|
| Interaction |
|
|---|
| Brite |
Therapeutic category of drugs in Japan [BR:br08301]
2 Agents affecting individual organs
21 Cardiovascular agents
211 Cardiotonics
2119 Others
D02042 Olprinone hydrochloride hydrate (JAN)
Drug groups [BR:br08330]
Cardiovascular agent
DG01703 Cardiotonic
DG01757 Amrinone type cardiotonic
DG01396 Olprinone
D02042 Olprinone hydrochloride hydrate
DG01507 Phosphodiesterase III inhibitor
DG01757 Amrinone type cardiotonic
DG01396 Olprinone
D02042 Olprinone hydrochloride hydrate
Target-based classification of drugs [BR:br08310]
Enzymes
Hydrolases (EC3)
Phosphodiesterases
PDE3
D02042 Olprinone hydrochloride hydrate (JAN) <JP>
Drug groups [BR:br08330]
Cardiovascular agent
DG01703 Cardiotonic
DG01757 Amrinone type cardiotonic
DG01396 Olprinone
DG01507 Phosphodiesterase III inhibitor
DG01757 Amrinone type cardiotonic
DG01396 Olprinone
|
|---|
| Other DBs |
|
|---|
| LinkDB |
|
|---|
| KCF data |
ATOM 21
1 C8y C 23.9802 -18.6439
2 C8y C 23.9802 -20.0460
3 N4x N 25.1954 -20.7471
4 C8y C 26.4106 -20.0460
5 C8y C 26.4106 -18.6439
6 C8x C 25.1954 -17.9428
7 O5x O 22.7650 -20.7471
8 C1a C 27.6257 -20.7471
9 C3b C 22.7650 -17.9428
10 N3a N 21.5498 -17.2418
11 C8y C 27.6257 -17.9428
12 C8x C 28.8409 -18.6439
13 N4y N 30.0561 -17.9428
14 C8y C 30.0561 -16.5407
15 C8x C 28.8409 -15.8396
16 C8x C 27.6257 -16.5407
17 C8x C 31.3648 -18.3635
18 C8x C 32.2061 -17.2418
19 N5x N 31.3648 -16.1201
20 X Cl 32.3867 -20.3700
21 O0 O 32.9000 -22.0500
BOND 21
1 1 2 1
2 2 3 1
3 3 4 1
4 4 5 2
5 5 6 1
6 1 6 2
7 2 7 2
8 4 8 1
9 1 9 1
10 9 10 3
11 5 11 1
12 11 12 2
13 12 13 1
14 13 14 1
15 14 15 1
16 15 16 2
17 11 16 1
18 13 17 1
19 17 18 2
20 18 19 1
21 14 19 2
|
|---|
