| Entry |
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| Name |
Dextran sulfate sodium (JAN);
MDS-Kowa A (TN) |
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| Formula |
(C11H12O28S6. 6Na)n
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| Structure |
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| Remark |
| Product (DG00180): | D02141<US> D03343<JP> D06539<US> |
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| Efficacy |
Antidyslipidemia (hypertriglyceridemic), Lipoprotein lipase (LPL) activator |
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| Target |
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| Pathway |
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| Interaction |
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| Structure map |
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| Brite |
Anatomical Therapeutic Chemical (ATC) classification [BR:br08303]
B BLOOD AND BLOOD FORMING ORGANS
B05 BLOOD SUBSTITUTES AND PERFUSION SOLUTIONS
B05A BLOOD AND RELATED PRODUCTS
B05AA Blood substitutes and plasma protein fractions
B05AA05 Dextran
D02047 Dextran sulfate sodium (JAN)
Target-based classification of drugs [BR:br08310]
Enzymes
Hydrolases (EC3)
Carboxylic-ester hydrolases
LIPC
D02047 Dextran sulfate sodium (JAN)
LPL
D02047 Dextran sulfate sodium (JAN)
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| Other DBs |
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| LinkDB |
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| KCF data |
ATOM 53
1 C1y C 22.9600 -13.1600
2 C1y C 22.9600 -14.5600
3 C1y C 24.1500 -15.2600
4 C1y C 25.4100 -14.5600
5 C1y C 25.4100 -13.1600
6 O2x O 24.1500 -12.4600
7 O1a O 21.7700 -12.4600
8 O2a O 24.1500 -16.6600
9 O2a O 21.7700 -15.2600
10 O2a O 26.6000 -15.2600
11 O2a O 26.6000 -12.4600
12 S4a S 20.3700 -15.2600
13 O1d O 18.9700 -15.2600 #-
14 S4a S 28.0000 -15.2600
15 O1d O 29.4000 -15.2600 #-
16 S4a S 24.1500 -18.0600
17 O1d O 24.1500 -19.4600 #-
18 O1d O 20.3700 -13.8600
19 O1d O 20.3700 -16.6600
20 O1d O 25.5500 -18.0600
21 O1d O 22.7500 -18.0600
22 O1d O 28.0000 -13.8600
23 O1d O 28.0000 -16.6600
24 Z * 15.0500 -12.4600
25 C1y C 29.1200 -12.0400
26 C1y C 29.1200 -10.6400
27 C1y C 30.3100 -9.9400
28 C1y C 31.5700 -10.6400
29 C1x C 31.5700 -12.0400
30 O2x O 30.3100 -12.7400
31 C1b C 27.9300 -12.7400
32 O2a O 30.3100 -8.5400
33 O2a O 27.9300 -9.9400
34 O2a O 32.7600 -9.9400
35 Z * 40.4600 -16.0300
36 S4a S 26.5300 -9.9400
37 O1d O 25.1300 -9.9400 #-
38 S4a S 34.1600 -9.9400
39 O1d O 35.5600 -9.9400 #-
40 S4a S 30.3100 -7.1400
41 O1d O 30.3100 -5.7400 #-
42 O1d O 26.5300 -11.3400
43 O1d O 26.5300 -8.5400
44 O1d O 31.7100 -7.1400
45 O1d O 28.9100 -7.1400
46 O1d O 34.1600 -11.3400
47 O1d O 34.1600 -8.5400
48 Z Na 17.0100 -15.1900 #+
49 Z Na 25.4800 -19.4600 #+
50 Z Na 30.8000 -15.3300 #+
51 Z Na 23.1700 -10.0100 #+
52 Z Na 31.6400 -5.7400 #+
53 Z Na 36.9600 -9.8700 #+
BOND 48
1 1 2 1
2 2 3 1
3 3 4 1
4 4 5 1
5 5 6 1
6 1 6 1
7 1 7 1 #Up
8 3 8 1 #Up
9 2 9 1 #Down
10 4 10 1 #Down
11 5 11 1 #Down
12 9 12 1
13 12 13 1
14 10 14 1
15 14 15 1
16 8 16 1
17 16 17 1
18 12 18 2
19 12 19 2
20 16 20 2
21 16 21 2
22 14 22 2
23 14 23 2
24 7 24 1
25 25 26 1
26 26 27 1
27 27 28 1
28 28 29 1
29 29 30 1
30 25 30 1
31 25 31 1 #Down
32 27 32 1 #Down
33 26 33 1 #Up
34 28 34 1 #Up
35 29 35 1
36 33 36 1
37 36 37 1
38 34 38 1
39 38 39 1
40 32 40 1
41 40 41 1
42 36 42 2
43 36 43 2
44 40 44 2
45 40 45 2
46 38 46 2
47 38 47 2
48 11 31 1
BRACKET 1 16.4500 -21.0000 16.4500 -4.3400
1 38.5700 -4.3400 38.5700 -21.0000
1 n
ORIGINAL 1 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16
1 17 18 19 20 21 22 23 25 26 27 28 29 30 31 32 33
1 34 36 37 38 39 40 41 42 43 44 45 46 47 48 49 50
1 51 52 53
REPEAT 1
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