| Entry |
|
|---|
| Name |
Clinprost (JAN/INN);
TEI 9090;
Arteron (TN) |
|---|
| Formula |
C22H36O4
|
|---|
| Exact mass |
364.2614
|
|---|
| Mol weight |
364.52
|
|---|
| Structure |
|
|---|
| Simcomp |
|
|---|
| Class |
Hormonal agent
DG01961 Prostaglandin derivative
DG01810 Prostacycline derivative
|
|---|
| Efficacy |
Vasodilator (peripheral), Platelet aggregation inhibitor, Prostaglandin I2 receptor agonist |
|---|
| Comment |
Prostacycline derivative
|
|---|
| Target |
|
|---|
| Pathway |
| hsa04080 | Neuroactive ligand-receptor interaction |
| hsa04270 | Vascular smooth muscle contraction |
|
|---|
| Interaction |
|
|---|
| Structure map |
| map07228 | Eicosanoid receptor agonists/antagonists |
|
|---|
| Brite |
Drug groups [BR:br08330]
Hormonal agent
DG01961 Prostaglandin derivative
DG01810 Prostacycline derivative
D02048 Clinprost
Target-based classification of drugs [BR:br08310]
G Protein-coupled receptors
Rhodopsin family
Prostacyclin
PTGIR
D02048 Clinprost (JAN/INN)
|
|---|
| Other DBs |
|
|---|
| LinkDB |
|
|---|
| KCF data |
ATOM 26
1 C1x C 8.1900 -21.4200
2 C1y C 9.0300 -22.5400
3 C1y C 10.3600 -22.0500
4 C1y C 10.3600 -20.6500
5 C1y C 9.0300 -20.2300
6 C2b C 11.6200 -22.7500
7 C2b C 12.8100 -22.0500
8 C1c C 14.0000 -22.6800
9 C1b C 15.1900 -21.9800
10 C1b C 16.4500 -22.6800
11 C1b C 17.6400 -21.9800
12 C1b C 18.8300 -22.6800
13 C1a C 20.0900 -21.9800
14 O1a O 14.0000 -24.0800
15 O1a O 8.5400 -23.8700
16 C1x C 11.2000 -19.5300
17 C2y C 10.3600 -18.4100
18 C2x C 9.0300 -18.8300
19 C1b C 10.7800 -17.0800
20 C1b C 11.9700 -16.3800
21 C1b C 13.1600 -17.0800
22 C1b C 14.3500 -16.3800
23 C7a C 15.5400 -17.0800
24 O7a O 16.7300 -16.3800
25 O6a O 15.5400 -18.4800
26 C1a C 17.9200 -17.0800
BOND 27
1 1 2 1
2 2 3 1
3 3 4 1
4 4 5 1
5 1 5 1
6 3 6 1 #Up
7 6 7 2
8 7 8 1
9 8 9 1
10 9 10 1
11 10 11 1
12 11 12 1
13 12 13 1
14 8 14 1 #Up
15 2 15 1 #Down
16 4 16 1 #Down
17 16 17 1
18 17 18 2
19 5 18 1 #Down
20 17 19 1
21 20 21 1
22 20 19 1
23 21 22 1
24 22 23 1
25 23 24 1
26 23 25 2
27 24 26 1
|
|---|
