| Entry |
|
|---|
| Name |
Tropisetron (INN);
Navoban (TN) |
|---|
| Formula |
C17H20N2O2
|
|---|
| Exact mass |
284.1525
|
|---|
| Mol weight |
284.35
|
|---|
| Structure |
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|---|
| Simcomp |
|
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| Class |
Gastrointestinal agent
DG01489 5-HT3-receptor antagonist
DG01762 Antiemetic
|
|---|
| Remark |
|
|---|
| Efficacy |
Anti-emetic, Serotonin 5-HT3 receptor antagonist |
|---|
| Target |
|
|---|
| Pathway |
|
|---|
| Interaction |
|
|---|
| Structure map |
| map07211 | Serotonin receptor agonists/antagonists |
|
|---|
| Brite |
Anatomical Therapeutic Chemical (ATC) classification [BR:br08303]
A ALIMENTARY TRACT AND METABOLISM
A04 ANTIEMETICS AND ANTINAUSEANTS
A04A ANTIEMETICS AND ANTINAUSEANTS
A04AA Serotonin (5HT3) antagonists
A04AA03 Tropisetron
D02130 Tropisetron (INN)
Drug groups [BR:br08330]
Gastrointestinal agent
DG01489 5-HT3-receptor antagonist
DG00062 Tropisetron
D02130 Tropisetron
DG01762 Antiemetic
DG00062 Tropisetron
D02130 Tropisetron
Target-based classification of drugs [BR:br08310]
Ion channels
Ligand-gated ion channels
Serotonin
HTR3
D02130 Tropisetron (INN)
Drug groups [BR:br08330]
Gastrointestinal agent
DG01489 5-HT3-receptor antagonist
DG00062 Tropisetron
DG01762 Antiemetic
DG00062 Tropisetron
|
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| Other DBs |
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| LinkDB |
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| KCF data |
ATOM 21
1 O7a O 32.6488 -10.2991
2 C1y C 31.5372 -9.6321
3 C1x C 30.5590 -8.1648
4 C1x C 30.5590 -9.1875
5 C1y C 29.1362 -8.1648
6 C1y C 29.0472 -9.1875
7 N1y N 28.2913 -7.2311
8 C1x C 28.1135 -8.7428
9 C1x C 27.5800 -9.8100
10 C1a C 28.2963 -5.9092
11 C7a C 34.0746 -10.2754
12 C8y C 34.7959 -9.0483
13 O6a O 34.7566 -11.5486
14 C8y C 36.1753 -8.9956
15 C8y C 36.4849 -7.6457
16 N4x N 35.2968 -6.9342
17 C8x C 34.2529 -7.8442
18 C8x C 37.2030 -9.9512
19 C8x C 38.5444 -9.5390
20 C8x C 38.8540 -8.1891
21 C8x C 37.8264 -7.2336
BOND 24
1 2 4 1
2 3 5 1
3 4 6 1
4 5 7 1
5 5 8 1
6 6 9 1
7 6 7 1
8 8 9 1
9 2 1 1 #Down
10 2 3 1
11 7 10 1
12 1 11 1
13 11 12 1
14 11 13 2
15 12 14 1
16 14 15 1
17 15 16 1
18 16 17 1
19 12 17 2
20 14 18 2
21 18 19 1
22 19 20 2
23 20 21 1
24 15 21 2
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