| Entry |
|
|---|
| Name |
Croconazole hydrochloride (JP18);
Pilzcin (TN) |
|---|
| Formula |
C18H15ClN2O. HCl
|
|---|
| Exact mass |
346.0640
|
|---|
| Mol weight |
347.23
|
|---|
| Structure |
|
|---|
| Simcomp |
|
|---|
| Class |
Antifungal
DG01883 Imidazole antifungal
|
|---|
| Remark |
|
|---|
| Efficacy |
Antifungal, Ergosterol biosynthesis inhibitor |
|---|
| Comment |
Imidazole derivative
|
|---|
| Target |
sterol 14alpha-demethylase [KO: K05917] |
|---|
| Pathway |
|
|---|
| Interaction |
|
|---|
| Structure map |
|
|---|
| Brite |
Drug groups [BR:br08330]
Antifungal
DG01883 Imidazole antifungal
DG01297 Croconazole
D02169 Croconazole hydrochloride
Antimicrobials [BR:br08307]
Antifungals
Ergosterol biosynthesis inhibitor
Imidazole
D02169 Croconazole hydrochloride (JP18)
Drugs listed in the Japanese Pharmacopoeia [BR:br08311]
Chemicals
D02169 Croconazole hydrochloride
Drug groups [BR:br08330]
Antifungal
DG01883 Imidazole antifungal
DG01297 Croconazole
Antimicrobials abbreviations [BR:br08327]
Antifungals
Ergosterol biosynthesis inhibitor
Imidazole
DG01297 Croconazole
|
|---|
| Other DBs |
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| LinkDB |
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| KCF data |
ATOM 23
1 C8x C 24.0097 -19.9517
2 C8x C 24.4299 -18.6445
3 N4y N 23.3095 -17.8043
4 C8x C 22.1890 -18.6445
5 N5x N 22.6092 -19.9517
6 C8y C 24.5232 -14.3497
7 C8y C 24.5232 -15.7036
8 C8x C 25.7370 -16.4505
9 C8x C 26.9508 -15.7503
10 C8x C 26.9508 -14.3497
11 C8x C 25.7370 -13.6028
12 C8x C 18.5010 -12.2490
13 C8x C 18.5010 -13.6495
14 C8x C 19.7148 -14.3497
15 C8y C 20.9286 -13.6495
16 C8x C 20.9286 -12.2490
17 C8y C 19.7148 -11.5487
18 C1b C 22.0957 -14.3497
19 O2a O 23.3095 -13.6028
20 C2c C 23.3095 -16.4038
21 C2a C 22.0957 -15.7036
22 X Cl 19.7148 -10.1482
23 X Cl 30.5899 -15.0033
BOND 24
1 11 6 1
2 1 2 2
3 2 3 1
4 3 4 1
5 4 5 2
6 5 1 1
7 12 13 2
8 13 14 1
9 14 15 2
10 15 16 1
11 16 17 2
12 17 12 1
13 6 7 2
14 15 18 1
15 7 8 1
16 18 19 1
17 19 6 1
18 8 9 2
19 7 20 1
20 20 3 1
21 9 10 1
22 20 21 2
23 10 11 2
24 17 22 1
|
|---|
