| Entry |
|
|---|
| Name |
Levallorphan tartrate (JP18);
Lorfan (TN) |
|---|
| Formula |
C19H25NO. C4H6O6
|
|---|
| Exact mass |
433.2101
|
|---|
| Mol weight |
433.49
|
|---|
| Structure |
|
|---|
| Simcomp |
|
|---|
| Remark |
| Therapeutic category: | 2213 |
| Product (mixture): | D03855<JP> |
|
|---|
| Efficacy |
Narcotic antagonist, Respiratory stimulant, Opioid receptor agonist/antagonist |
|---|
| Comment |
Morphinan derivative
|
|---|
| Target |
|
|---|
| Pathway |
| hsa04080 | Neuroactive ligand-receptor interaction |
|
|---|
| Structure map |
| map07224 | Opioid receptor agonists/antagonists |
|
|---|
| Brite |
Therapeutic category of drugs in Japan [BR:br08301]
2 Agents affecting individual organs
22 Respiratory organ agents
221 Respiratory stimulants
2213 Dimorpholamines
D02238 Levallorphan tartrate (JP18)
Target-based classification of drugs [BR:br08310]
G Protein-coupled receptors
Rhodopsin family
Opioid
OPRM1
D02238 Levallorphan tartrate (JP18) <JP>
OPRK1
D02238 Levallorphan tartrate (JP18) <JP>
OPRD1
D02238 Levallorphan tartrate (JP18) <JP>
Drugs listed in the Japanese Pharmacopoeia [BR:br08311]
Chemicals
D02238 Levallorphan tartrate
D02238 Levallorphan tartrate injection
|
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| Other DBs |
|
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| LinkDB |
|
|---|
| KCF data |
ATOM 31
1 O6a O 21.1500 -8.9104
2 C6a C 22.3114 -8.2135
3 C1c C 23.5193 -8.9104
4 C1c C 24.7271 -8.2135
5 C6a C 25.9350 -8.9104
6 O6a O 27.1429 -8.2135
7 O6a O 22.3114 -6.8198
8 O1a O 23.5193 -10.3505
9 O1a O 24.7271 -6.8198
10 O6a O 25.9350 -10.3505
11 C1z C 13.4694 -9.3694
12 C8y C 13.4694 -8.0454
13 C1y C 14.6540 -10.0661
14 C1x C 12.3545 -9.9965
15 C1x C 14.6540 -8.7423
16 C8x C 12.3545 -7.4183
17 C8y C 14.6540 -7.4183
18 C1y C 15.7689 -9.3694
19 C1x C 14.6540 -11.3204
20 C1x C 12.3545 -11.3204
21 C1x C 16.8837 -8.7423
22 C8y C 12.3545 -6.0944
23 C1x C 15.7689 -8.1151
24 C8x C 14.6540 -6.0944
25 N1y N 16.8837 -10.0661
26 C1x C 13.4694 -12.0172
27 C8x C 13.5391 -5.4673
28 O1a O 11.2397 -5.4673
29 C1b C 18.2826 -10.0661
30 C2b C 18.9855 -11.2834
31 C2a C 20.3699 -11.2832
BOND 33
1 1 2 1
2 2 3 1
3 3 4 1
4 4 5 1
5 5 6 1
6 2 7 2
7 3 8 1 #Up
8 4 9 1 #Up
9 5 10 2
10 11 12 1
11 11 13 1
12 11 14 1
13 11 15 1 #Up
14 12 16 2
15 12 17 1
16 13 18 1
17 13 19 1
18 14 20 1
19 15 21 1
20 16 22 1
21 17 23 1
22 17 24 2
23 18 25 1 #Up
24 19 26 1
25 22 27 2
26 22 28 1
27 18 23 1
28 20 26 1
29 21 25 1
30 24 27 1
31 25 29 1
32 29 30 1
33 30 31 2
|
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