| Entry |
|
|---|
| Name |
Levomepromazine maleate (JP18/USAN);
Hirnamin (TN) |
|---|
| Formula |
C19H24N2OS. C4H4O4
|
|---|
| Exact mass |
444.1719
|
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| Mol weight |
444.55
|
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| Structure |
|
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| Simcomp |
|
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| Class |
Neuropsychiatric agent
DG01478 Dopamine antagonist
DG01474 Dopamine D2-receptor antagonist
DG03200 Antipsychotic agent
DG01905 Phenothiazine antipsychotics
|
|---|
| Remark |
| Therapeutic category: | 1172 |
| Product (DG00868): | D02248<JP> |
|
|---|
| Efficacy |
Analgesic, Antipsychotic |
|---|
| Comment |
Phenothiazine derivative
|
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| Target |
|
|---|
| Pathway |
| hsa04080 | Neuroactive ligand-receptor interaction |
|
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| Interaction |
|
|---|
| Structure map |
| map07029 | Antipsychotics - phenothiazines |
|
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| Brite |
Anatomical Therapeutic Chemical (ATC) classification [BR:br08303]
N NERVOUS SYSTEM
N05 PSYCHOLEPTICS
N05A ANTIPSYCHOTICS
N05AA Phenothiazines with aliphatic side-chain
N05AA02 Levomepromazine
D02248 Levomepromazine maleate (JP18/USAN) <JP>
Therapeutic category of drugs in Japan [BR:br08301]
1 Agents affecting nervous system and sensory organs
11 Agents affecting central nervous system
117 Psychotropics
1172 Phenothiazines
D02248 Levomepromazine maleate (JP18/USAN)
Drug groups [BR:br08330]
Neuropsychiatric agent
DG01478 Dopamine antagonist
DG01474 Dopamine D2-receptor antagonist
DG00868 Levomepromazine
D02248 Levomepromazine maleate
DG03200 Antipsychotic agent
DG01905 Phenothiazine antipsychotics
DG00868 Levomepromazine
D02248 Levomepromazine maleate
Target-based classification of drugs [BR:br08310]
G Protein-coupled receptors
Rhodopsin family
Dopamine
DRD2
D02248 Levomepromazine maleate (JP18/USAN) <JP>
Drugs listed in the Japanese Pharmacopoeia [BR:br08311]
Chemicals
D02248 Levomepromazine maleate
Drug groups [BR:br08330]
Neuropsychiatric agent
DG01478 Dopamine antagonist
DG01474 Dopamine D2-receptor antagonist
DG00868 Levomepromazine
DG03200 Antipsychotic agent
DG01905 Phenothiazine antipsychotics
DG00868 Levomepromazine
|
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| Other DBs |
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| LinkDB |
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| KCF data |
ATOM 31
1 C8x C 16.1381 -21.1212
2 C8x C 16.1381 -22.5253
3 C8x C 17.3549 -23.2272
4 C8x C 17.3549 -20.4194
5 C8y C 18.5248 -21.1212
6 C8y C 18.5248 -22.5253
7 S2x S 19.7416 -23.2272
8 N1y N 19.6948 -20.4194
9 C8y C 20.9584 -21.1212
10 C8y C 20.9584 -22.5253
11 C8x C 22.1751 -23.2741
12 C8x C 23.3921 -22.5720
13 C8y C 23.3920 -21.1681
14 C8x C 22.1751 -20.4661
15 C1b C 19.6948 -19.0153
16 C1c C 20.9584 -18.3601
17 C1b C 20.9584 -16.9561
18 C1a C 22.1285 -19.0621
19 N1c N 22.1752 -16.2540
20 C1a C 22.1752 -14.8502
21 C1a C 23.3921 -16.9561
22 O2a O 24.6138 -20.4624
23 C1a C 25.8005 -21.1474
24 C6a C 33.8311 -21.1375
25 C2b C 33.1345 -19.9301
26 O6a O 33.1345 -22.2987
27 O6a O 35.1780 -21.1375
28 C2b C 31.5090 -19.9301
29 C6a C 30.8124 -21.1375
30 O6a O 29.4654 -21.1375
31 O6a O 31.5090 -22.2987
BOND 32
1 14 9 1
2 2 3 2
3 5 6 2
4 6 7 1
5 8 15 1
6 7 10 1
7 15 16 1
8 9 8 1
9 16 17 1
10 8 5 1
11 16 18 1 #Up
12 3 6 1
13 17 19 1
14 5 4 1
15 19 20 1
16 4 1 2
17 19 21 1
18 1 2 1
19 9 10 2
20 10 11 1
21 11 12 2
22 12 13 1
23 13 14 2
24 13 22 1
25 22 23 1
26 24 25 1
27 24 26 1
28 24 27 2
29 25 28 2
30 28 29 1
31 29 30 1
32 29 31 2
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