KEGG   DRUG: ApramycinHelp
Entry
D02322                      Drug                                   

Name
Apramycin (USAN/INN)
Formula
C21H41N5O11
Exact mass
539.2803
Mol weight
539.5771
Structure
Mol fileKCF fileDB search
Simcomp SIMCOMP
Source
Streptomyces tenebrarius [TAX:1933]
Class
Antibacterial
 DG01447  Aminoglycoside antibiotic
Remark
Same as: C01555
Efficacy
Antibacterial, Protein biosynthesis inhibitor
Target
30S ribosomal subunit
  Pathway
ko03010  Ribosome
Interaction
Drug interaction
Biosynthesis
map00524  Neomycin, kanamycin and gentamicin biosynthesis
Other DBs
CAS: 37321-09-8
PubChem: 7849381
ChEBI: 2790
ChEMBL: CHEMBL1230961 CHEMBL1909452
DrugBank: DB04626
PDB-CCD: AM2[PDBj]
LigandBox: D02322
NIKKAJI: J139.315D
LinkDB All DBs
KCF data Show

ATOM        37
            1   O1a O    19.4682  -23.1525
            2   C1y C    20.7357  -22.4483
            3   C1y C    21.9328  -23.1525
            4   C1x C    23.2002  -22.4483
            5   C1y C    23.2002  -21.0400
            6   C1y C    21.9328  -20.3359
            7   C1y C    20.7357  -21.0400
            8   N1a N    21.9328  -24.5608
            9   O1a O    19.5387  -20.3359
            10  N1a N    24.3973  -20.3359
            11  O2a O    21.9328  -18.9276
            12  C1y C    23.1298  -18.2234
            13  O2x O    24.3269  -18.9276
            14  C1y C    25.5944  -18.2234
            15  C1y C    25.5944  -16.8151
            16  C1x C    24.3973  -16.1110
            17  C1y C    23.1298  -16.8151
            18  N1a N    21.9328  -16.1110
            19  C1y C    26.7914  -18.9276
            20  C1y C    27.9885  -18.2234
            21  C1y C    27.9885  -16.8151
            22  O2x O    26.7914  -16.1110
            23  O2a O    29.1855  -16.1110
            24  N1b N    29.1855  -18.9276
            25  O1a O    26.7914  -20.3359
            26  C1a C    30.3826  -18.2234
            27  C1y C    30.3826  -13.9985
            28  C1y C    30.3826  -15.4068
            29  O2x O    31.5797  -16.1110
            30  C1y C    32.8471  -15.4068
            31  C1y C    32.8471  -13.9985
            32  C1y C    31.5797  -13.2944
            33  O1a O    29.1855  -13.2944
            34  N1a N    34.0442  -13.2944
            35  O1a O    31.5797  -11.8861
            36  C1b C    34.0442  -16.1110
            37  O1a O    35.2412  -15.4068
BOND        40
            1     2   1 1 #Down
            2     2   3 1
            3     3   4 1
            4     4   5 1
            5     5   6 1
            6     6   7 1
            7     2   7 1
            8     3   8 1 #Up
            9     7   9 1 #Up
            10    5  10 1 #Up
            11    6  11 1 #Down
            12   12  11 1 #Down
            13   12  13 1
            14   13  14 1
            15   14  15 1
            16   15  16 1
            17   16  17 1
            18   12  17 1
            19   17  18 1 #Down
            20   14  19 1
            21   19  20 1
            22   20  21 1
            23   21  22 1
            24   15  22 1
            25   21  23 1 #Down
            26   20  24 1 #Up
            27   19  25 1 #Up
            28   24  26 1
            29   27  28 1
            30   28  29 1
            31   29  30 1
            32   30  31 1
            33   31  32 1
            34   27  32 1
            35   28  23 1 #Down
            36   27  33 1 #Down
            37   31  34 1 #Down
            38   32  35 1 #Up
            39   30  36 1 #Up
            40   36  37 1

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