KEGG   DRUG: Carbutamide
Entry
D02425                      Drug                                   
Name
Carbutamide (INN);
Invenol (TN)
Formula
C11H17N3O3S
Exact mass
271.0991
Mol weight
271.336
Structure
Simcomp
Class
Antidiabetic agent
 DG01508  Sulfonylurea receptor agonist
  DG01734  Sulfonylurea
 DG02044  Hypoglycemic agent
  DG01734  Sulfonylurea
Remark
ATC code: A10BB06
Efficacy
Antidiabetic, Hypoglycemic, Sulfonylurea receptor agonist
Comment
Sulfonylurea
Target
ABCC8 (SUR1) [HSA:6833] [KO:K05032]
  Pathway
hsa02010  ABC transporters
hsa04911  Insulin secretion
hsa04930  Type II diabetes mellitus
Interaction
Structure map
map07018  Sulfonamide derivatives - hypoglycemic agents
map07055  Sulfonamide derivatives - overview
Brite
Anatomical Therapeutic Chemical (ATC) classification [BR:br08303]
 A ALIMENTARY TRACT AND METABOLISM
  A10 DRUGS USED IN DIABETES
   A10B BLOOD GLUCOSE LOWERING DRUGS, EXCL. INSULINS
    A10BB Sulfonylureas
     A10BB06 Carbutamide
      D02425  Carbutamide (INN)
Drug groups [BR:br08330]
 Antidiabetic agent
  DG01508  Sulfonylurea receptor agonist
   DG01734  Sulfonylurea
    D02425  Carbutamide
  DG02044  Hypoglycemic agent
   DG01734  Sulfonylurea
    D02425  Carbutamide
Target-based classification of drugs [BR:br08310]
 Transporters
  ABC transporters
   ABCC subfamily
    ABCC8 (SUR1)
     D02425  Carbutamide (INN)
Other DBs
CAS: 339-43-5
PubChem: 7849483
LigandBox: D02425
NIKKAJI: J5.684G
LinkDB
KCF data

ATOM        18
            1   C8y C    18.8472  -12.3307
            2   S4a S    20.0124  -11.6315
            3   C8x C    17.6354  -11.6315
            4   C8x C    18.8472  -13.6357
            5   N1b N    21.5505  -12.3773
            6   O3c O    20.8048  -10.4197
            7   O3c O    19.0336  -10.3731
            8   C8x C    16.4236  -12.2841
            9   C8x C    17.6354  -14.3815
            10  C5a C    22.6691  -11.6315
            11  C8y C    16.4236  -13.6824
            12  N1b N    23.8810  -12.2841
            13  O5a O    22.6691  -10.2799
            14  N1a N    15.2583  -14.3815
            15  C1b C    24.9996  -11.5383
            16  C1b C    26.1647  -12.2375
            17  C1b C    27.3766  -11.4917
            18  C1a C    28.4486  -12.0977
BOND        18
            1     1   2 1
            2     1   3 1
            3     1   4 2
            4     2   5 1
            5     2   6 2
            6     2   7 2
            7     3   8 2
            8     4   9 1
            9     5  10 1
            10    8  11 1
            11   10  12 1
            12   10  13 2
            13   11  14 1
            14   12  15 1
            15   15  16 1
            16   16  17 1
            17   17  18 1
            18    9  11 2

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