KEGG   DRUG: GliquidoneHelp
Entry
D02430                      Drug                                   

Name
Gliquidone (INN);
Glurenorm (TN)
Formula
C27H33N3O6S
Exact mass
527.209
Mol weight
527.6324
Structure
Mol fileKCF fileDB search
Class
Antidiabetic agent
 DG01790  Sulfonamide hypoglycemic
  DG01734  Sulfonamide type sulfonylurea receptor agonist
 DG01508  Sulfonylurea receptor agonist
 DG02044  Hypoglycemics
  DG01790  Sulfonamide hypoglycemic
   DG01734  Sulfonamide type sulfonylurea receptor agonist
Remark
ATC code: A10BB08
Efficacy
Antidiabetic, Hypoglycemic, Sulfonylurea receptor agonist
Comment
Sulfonylurea
Target
ABCC8 (SUR1) [HSA:6833] [KO:K05032]
  Pathway
hsa02010  ABC transporters
hsa04911  Insulin secretion
hsa04930  Type II diabetes mellitus
Interaction
Drug interaction
Brite
Anatomical Therapeutic Chemical (ATC) classification [BR:br08303]
 A ALIMENTARY TRACT AND METABOLISM
  A10 DRUGS USED IN DIABETES
   A10B BLOOD GLUCOSE LOWERING DRUGS, EXCL. INSULINS
    A10BB Sulfonylureas
     A10BB08 Gliquidone
      D02430  Gliquidone (INN)
Target-based classification of drugs [BR:br08310]
 Transporters
  ABC transporters
   ABCC subfamily
    ABCC8 (SUR1)
     D02430  Gliquidone (INN)
BRITE hierarchy
Other DBs
CAS: 33342-05-1
PubChem: 7849488
ChEMBL: CHEMBL383634
DrugBank: DB01251
LigandBox: D02430
NIKKAJI: J19.880C
LinkDB All DBs
KCF data Show

ATOM        37
            1   C8y C    21.0700  -14.9800
            2   C8x C    19.8100  -14.2800
            3   C8x C    21.0700  -16.3800
            4   S4a S    22.2600  -14.2800
            5   C8x C    18.6200  -14.9800
            6   C8x C    19.8100  -17.0800
            7   N1b N    23.4500  -14.9800
            8   C8y C    18.6200  -16.3800
            9   C5a C    24.7100  -14.2800
            10  C1b C    17.4300  -17.0800
            11  N1b N    25.8300  -14.9800
            12  O5a O    24.7100  -12.8800
            13  C1b C    16.1700  -16.3800
            14  C1y C    27.0900  -14.2800
            15  N1y N    15.0500  -17.0800
            16  C1x C    27.0900  -12.8800
            17  C1x C    28.2800  -14.9800
            18  C5x C    13.7900  -16.3800
            19  C1x C    28.2800  -12.1800
            20  C1x C    29.4700  -14.2800
            21  C8y C    12.6000  -17.0800
            22  O5x O    13.7900  -14.9800
            23  C1x C    29.4700  -12.8800
            24  C8y C    12.6000  -18.4100
            25  C8x C    11.4100  -16.3800
            26  C8x C    11.4100  -19.1100
            27  C8y C    10.1500  -17.0800
            28  C8x C    10.1500  -18.4100
            29  C5x C    15.0500  -18.4800
            30  C1z C    13.7900  -19.1100
            31  O5x O    16.2400  -19.1800
            32  C1a C    14.7000  -20.2300
            33  C1a C    12.8800  -20.1600
            34  O2a O     8.9600  -16.3800
            35  C1a C     7.7700  -17.0800
            36  O3c O    23.2499  -13.2901
            37  O3c O    21.2701  -13.2901
BOND        40
            1     1   2 2
            2     1   3 1
            3     1   4 1
            4     2   5 1
            5     3   6 2
            6     4   7 1
            7     5   8 2
            8     7   9 1
            9     8  10 1
            10    9  11 1
            11    9  12 2
            12   10  13 1
            13   11  14 1
            14   13  15 1
            15   14  16 1
            16   14  17 1
            17   15  18 1
            18   16  19 1
            19   17  20 1
            20   18  21 1
            21   18  22 2
            22   19  23 1
            23   21  24 1
            24   21  25 2
            25   24  26 2
            26   25  27 1
            27   26  28 1
            28    6   8 1
            29   20  23 1
            30   27  28 2
            31   15  29 1
            32   24  30 1
            33   30  29 1
            34   29  31 2
            35   30  32 1
            36   30  33 1
            37   27  34 1
            38   34  35 1
            39    4  36 2
            40    4  37 2

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