Entry |
|
Name |
Sulfamethazine (USP); Sulfadimidine (INN); Sulfamezathine (TN) |
Formula |
C12H14N4O2S
|
Exact mass |
278.0837
|
Mol weight |
278.33
|
Structure |

|
Simcomp |
|
Class |
Antibacterial
DG01787 Sulfonamide antibacterial
DG01784 Short-acting sulfonamide
|
Remark |
|
Efficacy |
Antibacterial, Folic acid biosynthesis inhibitor |
Target |
dihydropteroate synthase [KO: K00796] |
Interaction |
|
Structure map |
map07016 | Sulfonamide derivatives - sulfa drugs |
|
Brite |
Anatomical Therapeutic Chemical (ATC) classification [BR:br08303]
J ANTIINFECTIVES FOR SYSTEMIC USE
J01 ANTIBACTERIALS FOR SYSTEMIC USE
J01E SULFONAMIDES AND TRIMETHOPRIM
J01EB Short-acting sulfonamides
J01EB03 Sulfadimidine
D02436 Sulfamethazine (USP)
Drug groups [BR:br08330]
Antibacterial
DG01787 Sulfonamide antibacterial
DG01784 Short-acting sulfonamide
DG00597 Sulfadimidine
D02436 Sulfamethazine
Antimicrobials [BR:br08307]
Antibacterials
Folic acid biosynthesis inhibitor
Short-acting sulfonamide
D02436 Sulfamethazine (USP)
Drug groups [BR:br08330]
Antibacterial
DG01787 Sulfonamide antibacterial
DG01784 Short-acting sulfonamide
DG00597 Sulfadimidine
|
Other DBs |
|
LinkDB |
|
KCF data |
ATOM 19
1 C8y C 24.3520 -17.7632
2 S4a S 25.5660 -17.0628
3 C8x C 24.3520 -19.1641
4 C8x C 23.1846 -17.0628
5 N1b N 26.7801 -17.7632
6 O3c O 26.5466 -16.0822
7 O3c O 24.5854 -16.0822
8 C8x C 23.1846 -19.8645
9 C8x C 21.9705 -17.7632
10 C8y C 27.9942 -17.0628
11 C8y C 21.9705 -19.1641
12 N5x N 27.9942 -15.6619
13 N5x N 29.2083 -17.7632
14 N1a N 20.7564 -19.8645
15 C8y C 29.2083 -14.9615
16 C8y C 30.4691 -17.0628
17 C8x C 30.4691 -15.6619
18 C1a C 31.6831 -17.7632
19 C1a C 29.1970 -13.5606
BOND 20
1 1 2 1
2 1 3 2
3 1 4 1
4 2 5 1
5 2 6 2
6 2 7 2
7 3 8 1
8 4 9 2
9 5 10 1
10 8 11 2
11 10 12 2
12 10 13 1
13 11 14 1
14 12 15 1
15 13 16 2
16 15 17 2
17 9 11 1
18 16 17 1
19 16 18 1
20 15 19 1
|