KEGG   DRUG: RufloxacinHelp
Entry
D02474                      Drug                                   

Name
Rufloxacin (INN)
Formula
C17H18FN3O3S
Exact mass
363.1053
Mol weight
363.4065
Structure
Mol fileKCF fileDB search
Simcomp SIMCOMP
Class
Antibacterial
 DG01550  Quinolone
  DG01549  Fluoroquinolone
Other
 DG01529  Topoisomerase inhibitor
  DG01528  Topoisomerase IV inhibitor
Remark
Same as: C11240
ATC code: J01MA10
Chemical structure group: DG00622
Efficacy
Antibacterial, Nucleic acid biosynthesis inhibitor
Target
DNA gyrase [KO:K02469 K02470]
topoisomerase IV [KO:K02621 K02622]
Interaction
Drug interaction
Brite
Anatomical Therapeutic Chemical (ATC) classification [BR:br08303]
 J ANTIINFECTIVES FOR SYSTEMIC USE
  J01 ANTIBACTERIALS FOR SYSTEMIC USE
   J01M QUINOLONE ANTIBACTERIALS
    J01MA Fluoroquinolones
     J01MA10 Rufloxacin
      D02474  Rufloxacin (INN)
BRITE hierarchy
Other DBs
CAS: 101363-10-4
PubChem: 7849529
ChEBI: 8909
ChEMBL: CHEMBL295619
LigandBox: D02474
LinkDB All DBs
KCF data Show

ATOM        25
            1   C8y C    23.3821  -16.4047
            2   C8y C    22.1687  -17.1047
            3   C8y C    23.3821  -15.0045
            4   N4y N    24.5955  -17.1047
            5   C8y C    20.9552  -16.3581
            6   S2x S    22.1687  -18.5049
            7   C8y C    24.5955  -14.3045
            8   C8x C    22.1687  -14.2112
            9   C8x C    25.8556  -16.4514
            10  C1x C    24.5955  -18.5516
            11  N1y N    19.8351  -17.1047
            12  C8y C    20.9552  -14.9112
            13  C1x C    23.3821  -19.2049
            14  C8y C    25.8556  -15.0045
            15  O5x O    24.5955  -12.9043
            16  C1x C    19.8351  -18.5516
            17  C1x C    18.5749  -16.5447
            18  X   F    19.7885  -14.2112
            19  C6a C    26.9757  -14.4445
            20  C1x C    18.6684  -19.2983
            21  C1x C    17.3615  -17.2447
            22  O6a O    26.9757  -13.0443
            23  O6a O    28.0958  -15.0979
            24  N1y N    17.3615  -18.6916
            25  C1a C    16.1947  -19.4383
BOND        28
            1     1   2 1
            2     1   3 2
            3     1   4 1
            4     2   5 2
            5     2   6 1
            6     3   7 1
            7     3   8 1
            8     4   9 1
            9     4  10 1
            10    5  11 1
            11    5  12 1
            12    6  13 1
            13    7  14 1
            14    7  15 2
            15   11  16 1
            16   11  17 1
            17   12  18 1
            18   14  19 1
            19   16  20 1
            20   17  21 1
            21   19  22 2
            22   19  23 1
            23   20  24 1
            24   24  25 1
            25    8  12 2
            26    9  14 2
            27   10  13 1
            28   21  24 1

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