KEGG   DRUG: Tilmicosin
Entry
D02492                      Drug                                   

Name
Tilmicosin (USP/INN);
TMS;
Micotil (TN)
Formula
C46H80N2O13
Exact mass
868.566
Mol weight
869.133
Structure
Simcomp
Class
Antibacterial
 DG01551  Macrolide antibiotic
  DG01876  16-Membered ring macrolide antibiotic
Remark
Chemical structure group: DG01435
Efficacy
Antibacterial (veterinary), Protein biosynthesis inhibitor
Target
50S ribosomal subunit
  Pathway
ko03010  Ribosome
Interaction
Structure map
map07020  Macrolides and ketolides
Brite
Drug groups [BR:br08330]
 Antibacterial
  DG01551  Macrolide antibiotic
   DG01876  16-Membered ring macrolide antibiotic
    DG01435  Tilmicosin
     D02492  Tilmicosin
Antimicrobials [BR:br08307]
 Antibacterials
  Protein biosynthesis inhibitor
   Macrolide
    D02492  Tilmicosin (USP/INN)
Drug groups [BR:br08330]
 Antibacterial
  DG01551  Macrolide antibiotic
   DG01876  16-Membered ring macrolide antibiotic
    DG01435  Tilmicosin
Other DBs
CAS: 108050-54-0
PubChem: 7849536
ChEMBL: CHEMBL1908333
LigandBox: D02492
NIKKAJI: J410.842F
LinkDB
KCF data

ATOM        61
            1   C2x C    20.5100  -12.1100
            2   C2x C    20.5100  -13.4400
            3   C2y C    19.3200  -14.0700
            4   C1x C    22.7500  -13.4400
            5   C1a C    21.6300  -15.4000
            6   C1x C    21.6300  -17.9900
            7   C1y C    22.7500  -17.2900
            8   C1y C    22.7500  -16.0300
            9   O6a O    20.5100  -16.0300
            10  C2x C    19.3200  -15.4000
            11  C1y C    18.2700  -16.0300
            12  C1y C    18.2700  -17.3600
            13  O7x O    19.3900  -17.9900
            14  C7x C    20.5100  -17.3600
            15  C1y C    23.8700  -14.0700
            16  C1y C    23.8700  -15.4000
            17  C1b C    24.9900  -13.4400
            18  C1b C    26.1100  -14.1400
            19  C5x C    21.6300  -11.4800
            20  C1y C    22.7500  -12.1800
            21  O5x O    21.6300  -10.2200
            22  C1b C    17.1500  -17.9900
            23  O1a O    23.8700  -17.9900
            24  C1y C    22.7500  -20.0900
            25  C1y C    22.7500  -21.3500
            26  C1y C    23.9400  -21.9800
            27  C1y C    25.0600  -21.3500
            28  C1y C    25.0600  -20.0900
            29  O2x O    23.9400  -19.3900
            30  O1a O    26.1800  -21.9800
            31  N1c N    23.9400  -23.3100
            32  C1a C    22.8200  -23.9400
            33  C1a C    25.0600  -23.9400
            34  C1a C    21.6300  -19.3900
            35  O1a O    21.6300  -21.9800
            36  O2a O    27.0900  -18.0600
            37  C1a C    23.8700  -11.4800
            38  C1a C    17.1500  -19.3200
            39  C1b C    17.0800  -15.4000
            40  O2a O    15.9600  -16.0300
            41  C1y C    14.8400  -15.4000
            42  C1y C    14.8400  -14.1400
            43  C1y C    13.7200  -13.4400
            44  C1y C    12.6000  -14.1400
            45  C1y C    12.6000  -15.4000
            46  O2x O    13.7200  -16.0300
            47  C1a C    11.4800  -16.1000
            48  O1a O    11.4800  -13.4400
            49  O2a O    13.7200  -12.1800
            50  C1a C    12.6000  -11.5500
            51  O2a O    15.9600  -13.4400
            52  C1a C    15.9600  -12.1800
            53  C1a C    18.2000  -13.4400
            54  N1y N    27.2300  -13.4400
            55  C1x C    28.3500  -14.1400
            56  C1y C    29.4700  -13.5100
            57  C1x C    29.4700  -12.1800
            58  C1y C    28.3500  -11.5500
            59  C1x C    27.2300  -12.1800
            60  C1a C    30.5900  -14.1400
            61  C1a C    28.3500  -10.2200
BOND        64
            1    14   9 2
            2    26  31 1 #Up
            3     1   2 2
            4    31  32 1
            5     2   3 1
            6    31  33 1
            7    14   6 1
            8    24  34 1 #Up
            9    15  16 1
            10   25  35 1 #Down
            11   18  17 1
            12   28  36 1 #Up
            13   16  36 1 #Down
            14   15  17 1 #Down
            15   20  37 1 #Down
            16    6   7 1
            17   22  38 1
            18    7   8 1
            19   11  39 1 #Up
            20    8   5 1 #Down
            21   39  40 1
            22    3  10 2
            23   41  40 1 #Down
            24   19  20 1
            25   19  21 2
            26    4  20 1
            27   12  22 1 #Down
            28    8  16 1
            29   41  42 1
            30   42  43 1
            31   43  44 1
            32   44  45 1
            33   45  46 1
            34   46  41 1
            35    7  23 1 #Down
            36   45  47 1 #Down
            37   15   4 1
            38   44  48 1 #Up
            39   19   1 1
            40   43  49 1 #Up
            41   49  50 1
            42   10  11 1
            43   42  51 1 #Up
            44   11  12 1
            45   51  52 1
            46   12  13 1
            47    3  53 1
            48   24  25 1
            49   18  54 1
            50   25  26 1
            51   26  27 1
            52   27  28 1
            53   28  29 1
            54   29  24 1
            55   54  55 1
            56   55  56 1
            57   56  57 1
            58   57  58 1
            59   58  59 1
            60   59  54 1
            61   13  14 1
            62   56  60 1 #Down
            63   27  30 1 #Down
            64   58  61 1 #Down

» Japanese version   » Back

DBGET integrated database retrieval system