KEGG   DRUG: RifalazilHelp
Entry
D02550                      Drug                                   

Name
Rifalazil (USAN/INN);
RLZ
Formula
C51H64N4O13
Exact mass
940.447
Mol weight
941.0729
Structure
Mol fileKCF fileDB search
Simcomp SIMCOMP
Class
Antibacterial
 DG01598  Rifamycin antibiotic
 DG01966  Antitubercular
  DG01598  Rifamycin antibiotic
Efficacy
Antibacterial (antimycobacterial)
Comment
Rifamycin derivative
Target
DNA-directed RNA polymerase subunit beta [KO:K03043]
Interaction
Drug interaction
Structure map
map07023  Rifamycins
Other DBs
CAS: 129791-92-0
PubChem: 17396721
ChEMBL: CHEMBL236297
LigandBox: D02550
NIKKAJI: J406.601D
LinkDB All DBs
KCF data Show

ATOM        68
            1   C1c C    29.5400   -4.7600
            2   C1c C    29.5400   -6.2300
            3   O1a O    31.9900   -6.1600
            4   C1c C    31.9900   -4.7600
            5   C1c C    30.7300   -4.0600
            6   C2b C    34.3700   -4.7600
            7   C1c C    33.1800   -4.0600
            8   C5a C    35.6300   -6.9300
            9   C2c C    36.8200   -6.2300
            10  C2b C    36.8200   -4.7600
            11  C2b C    35.6300   -4.0600
            12  C1a C    33.1800   -2.6600
            13  C1a C    30.7300   -2.6600
            14  O1a O    28.3500   -4.0600
            15  C1a C    38.0100   -6.9300
            16  O5a O    34.4400   -6.2300
            17  N1b N    35.6300   -8.6100
            18  C1c C    28.3500   -6.9300
            19  O7a O    27.1600   -6.2300
            20  C1c C    28.3500   -8.6100
            21  C8y C    34.4400   -9.3100
            22  C8y C    34.4400  -10.7100
            23  C8y C    33.1800   -8.6100
            24  C8y C    31.9900   -9.3100
            25  C8y C    31.9900  -10.7100
            26  C8y C    33.1800  -11.4100
            27  C8y C    30.8000   -8.6100
            28  C8y C    29.5400   -9.3100
            29  C8y C    29.5400  -10.7100
            30  C8y C    30.8000  -11.4100
            31  O5x O    33.1800   -7.2100
            32  O1a O    30.8000   -7.2100
            33  C1a C    28.3500   -5.1100
            34  C7a C    25.9000   -5.5300
            35  C1a C    24.7100   -6.2300
            36  O6a O    25.9000   -4.1300
            37  C1c C    27.1600   -9.3100
            38  O2a O    25.9700   -8.6100
            39  C2b C    27.1600  -10.7100
            40  C1a C    27.1600   -7.6300
            41  C1a C    24.7800   -9.3100
            42  C2b C    25.9700  -11.4100
            43  O2a O    25.9700  -12.8100
            44  O2x O    28.3500  -11.4100
            45  C1z C    28.3500  -12.8100
            46  C5x C    30.8000  -12.8100
            47  C1a C    28.3500  -14.2100
            48  C1a C    29.5400   -7.9100
            49  N5x N    33.1569  -12.8098
            50  C8y C    34.3576  -13.5297
            51  C8y C    35.6176  -12.8297
            52  O2x O    35.6407  -11.4299
            53  C8y C    34.4045  -14.9295
            54  C8x C    35.5352  -15.6494
            55  C8y C    36.7952  -14.9494
            56  C8x C    36.8183  -13.5496
            57  O1a O    33.1716  -15.6338
            58  N1y N    38.0278  -15.6880
            59  C1x C    38.0051  -17.0800
            60  C1x C    39.2059  -17.7997
            61  N1y N    40.4296  -17.1196
            62  C1x C    40.4523  -15.7276
            63  C1x C    39.2515  -15.0079
            64  C1b C    41.6664  -17.8604
            65  C1c C    42.8817  -17.1844
            66  C1a C    44.0877  -17.9070
            67  C1a C    42.9040  -15.7500
            68  O5x O    31.9508  -13.4801
BOND        74
            1     1   2 1
            2     4   3 1 #Down
            3     4   5 1
            4     1   5 1
            5     6   7 1
            6     4   7 1
            7     8   9 1
            8     9  10 2
            9    10  11 1
            10    6  11 2
            11    7  12 1 #Up
            12    5  13 1 #Down
            13    1  14 1 #Down
            14    9  15 1
            15    8  16 2
            16    8  17 1
            17    2  18 1
            18   18  19 1 #Up
            19   18  20 1
            20   17  21 1
            21   21  22 2
            22   21  23 1
            23   23  24 1
            24   24  25 1
            25   25  26 1
            26   24  27 2
            27   27  28 1
            28   28  29 2
            29   29  30 1
            30   25  30 2
            31   23  31 2
            32   27  32 1
            33    2  33 1 #Up
            34   19  34 1
            35   34  35 1
            36   34  36 2
            37   26  22 1
            38   20  37 1
            39   37  38 1 #Down
            40   37  39 1
            41   20  40 1 #Down
            42   38  41 1
            43   39  42 2
            44   42  43 1
            45   29  44 1
            46   44  45 1
            47   43  45 1
            48   30  46 1
            49   45  46 1
            50   45  47 1 #Down
            51   28  48 1
            52   26  49 2
            53   49  50 1
            54   50  51 1
            55   51  52 1
            56   22  52 1
            57   50  53 2
            58   53  54 1
            59   54  55 2
            60   55  56 1
            61   51  56 2
            62   53  57 1
            63   55  58 1
            64   58  59 1
            65   59  60 1
            66   60  61 1
            67   61  62 1
            68   62  63 1
            69   58  63 1
            70   61  64 1
            71   64  65 1
            72   65  66 1
            73   65  67 1
            74   68  46 2

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