| Entry |
|
|---|
| Name |
Ravuconazole (prop.INN) |
|---|
| Formula |
C22H17F2N5OS
|
|---|
| Exact mass |
437.1122
|
|---|
| Mol weight |
437.47
|
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| Structure |
|
|---|
| Simcomp |
|
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| Class |
Antifungal
DG01523 Triazole antifungal
Metabolizing enzyme inhibitor
DG02852 CYP3A/CYP3A4 inhibitor
|
|---|
| Remark |
| Product (DG02844): | D10762<JP> |
|
|---|
| Efficacy |
Antifungal, Ergosterol biosynthesis inhibitor |
|---|
| Comment |
Triazole derivative
|
|---|
| Target |
sterol 14alpha-demethylase [KO: K05917] |
|---|
| Pathway |
|
|---|
| Interaction |
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| Structure map |
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| Brite |
Drug groups [BR:br08330]
Antifungal
DG01523 Triazole antifungal
DG02844 Ravuconazole
D02556 Ravuconazole (prop.INN)
Metabolizing enzyme inhibitor
DG02852 CYP3A/CYP3A4 inhibitor
DG02844 Ravuconazole
D02556 Ravuconazole (prop.INN)
Antimicrobials [BR:br08307]
Antifungals
Ergosterol biosynthesis inhibitor
Triazole
D02556 Ravuconazole (prop.INN)
Drug metabolizing enzymes and transporters [br08309.html]
Drug metabolizing enzymes
D02556
Drug groups [BR:br08330]
Antifungal
DG01523 Triazole antifungal
DG02844 Ravuconazole
Metabolizing enzyme inhibitor
DG02852 CYP3A/CYP3A4 inhibitor
DG02844 Ravuconazole
Antimicrobials abbreviations [BR:br08327]
Antifungals
Ergosterol biosynthesis inhibitor
Triazole
DG02844 Ravuconazole
|
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| Other DBs |
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| LinkDB |
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| KCF data |
ATOM 31
1 C8y C 33.7417 -16.4663
2 C1c C 34.9355 -15.7641
3 C1d C 36.1995 -16.4663
4 C1a C 34.9355 -14.3597
5 S2x S 33.3204 -17.8005
6 C8x C 31.9159 -17.8005
7 C8y C 31.4946 -16.4663
8 N5x N 32.6181 -15.6237
9 C8x C 27.8430 -15.7641
10 C8y C 27.8430 -14.3597
11 C8x C 29.0368 -13.6575
12 C8x C 30.3008 -14.3597
13 C8y C 30.3008 -15.7641
14 C8x C 29.0368 -16.4663
15 C3b C 26.6493 -13.6575
16 N3a N 25.4555 -12.9552
17 C8y C 36.1995 -17.8708
18 C1b C 37.3932 -15.7641
19 N4y N 37.3932 -14.3597
20 N5x N 36.2697 -13.5872
21 C8x C 36.6910 -12.2530
22 N5x N 38.0954 -12.2530
23 C8x C 38.5168 -13.5170
24 C8y C 37.4634 -18.5730
25 C8x C 37.4634 -19.9774
26 C8y C 36.2697 -20.6796
27 C8x C 35.0057 -19.9774
28 C8x C 35.0057 -18.5730
29 X F 36.2697 -22.0841
30 X F 38.6572 -17.8005
31 O1a O 37.4634 -16.8877
BOND 34
1 1 2 1
2 2 3 1
3 2 4 1 #Down
4 5 6 1
5 6 7 2
6 7 8 1
7 8 1 2
8 5 1 1
9 9 10 2
10 10 11 1
11 11 12 2
12 12 13 1
13 13 14 2
14 9 14 1
15 13 7 1
16 10 15 1
17 15 16 3
18 3 17 1
19 3 18 1
20 18 19 1
21 19 20 1
22 20 21 2
23 21 22 1
24 22 23 2
25 19 23 1
26 17 24 2
27 24 25 1
28 25 26 2
29 26 27 1
30 27 28 2
31 17 28 1
32 26 29 1
33 24 30 1
34 3 31 1 #Up
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