KEGG   DRUG: Methoxypromazine maleate
Entry
D02605                      Drug                                   

Name
Methoxypromazine maleate
Formula
C18H22N2OS. C4H4O4
Exact mass
430.1562
Mol weight
430.5172
Structure
Simcomp
Class
Neuropsychiatric agent
 DG01478  Dopamine antagonist
  DG01474  Dopamine D2-receptor antagonist
 DG03200  Antipsychotic agent
  DG01905  Phenothiazine antipsychotics
Efficacy
Antipsychotic, Dopamine D2 receptor antagonist
Comment
Phenothiazine derivative
Target
DRD2 [HSA:1813] [KO:K04145]
  Pathway
hsa04080  Neuroactive ligand-receptor interaction
hsa04540  Gap junction
Interaction
Structure map
map07029  Antipsychotics - phenothiazines
Brite
Drug groups [BR:br08330]
 Neuropsychiatric agent
  DG01478  Dopamine antagonist
   DG01474  Dopamine D2-receptor antagonist
    D02605  Methoxypromazine maleate
  DG03200  Antipsychotic agent
   DG01905  Phenothiazine antipsychotics
    D02605  Methoxypromazine maleate
Target-based classification of drugs [BR:br08310]
 G Protein-coupled receptors
  Rhodopsin family
   Dopamine
    DRD2
     D02605  Methoxypromazine maleate
Other DBs
CAS: 3403-42-7
PubChem: 17396775
ChEMBL: CHEMBL2104822
LigandBox: D02605
NIKKAJI: J220.159C
LinkDB
KCF data

ATOM        30
            1   C8x C    22.5471  -19.2822
            2   C8x C    22.5471  -20.6738
            3   C8x C    23.7522  -21.3696
            4   C8y C    24.9574  -20.6738
            5   C8y C    24.9574  -19.2822
            6   C8x C    23.7522  -18.5864
            7   S2x S    26.1626  -21.3696
            8   C8y C    27.3677  -20.6738
            9   C8y C    27.3677  -19.2822
            10  N1y N    26.1626  -18.5864
            11  C8x C    28.5730  -21.3696
            12  C8x C    29.7781  -20.6738
            13  C8y C    29.7781  -19.2822
            14  C8x C    28.5730  -18.5864
            15  C1b C    26.1626  -17.1948
            16  C1b C    27.3698  -16.4978
            17  C1a C    29.7393  -15.1019
            18  O2a O    30.9873  -18.5841
            19  C1a C    32.1776  -19.2715
            20  C1b C    28.5920  -17.2032
            21  N1c N    29.7731  -16.5211
            22  C1a C    30.9677  -17.2108
            23  C2b C    37.7852  -17.3339
            24  C2b C    39.5247  -17.3339
            25  C6a C    37.0894  -18.5391
            26  C6a C    40.2205  -18.5391
            27  O6a O    41.6121  -18.5391
            28  O6a O    35.6978  -18.5391
            29  O6a O    37.7757  -19.7274
            30  O6a O    39.5343  -19.7274
BOND        31
            1     1   2 1
            2     2   3 2
            3     3   4 1
            4     4   5 2
            5     5   6 1
            6     1   6 2
            7     4   7 1
            8     7   8 1
            9     8   9 2
            10    9  10 1
            11    5  10 1
            12    8  11 1
            13   11  12 2
            14   12  13 1
            15   13  14 2
            16    9  14 1
            17   10  15 1
            18   15  16 1
            19   13  18 1
            20   18  19 1
            21   16  20 1
            22   20  21 1
            23   21  22 1
            24   21  17 1
            25   23  24 2
            26   23  25 1
            27   24  26 1
            28   26  27 2
            29   25  28 1
            30   25  29 2
            31   26  30 1

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