| Entry |
|
|---|
| Name |
Trifluperidol (USAN/INN);
Triperidol (TN) |
|---|
| Formula |
C22H23F4NO2
|
|---|
| Exact mass |
409.1665
|
|---|
| Mol weight |
409.42
|
|---|
| Structure |
|
|---|
| Simcomp |
|
|---|
| Class |
Neuropsychiatric agent
DG01478 Dopamine antagonist
DG01474 Dopamine D2-receptor antagonist
DG03200 Antipsychotic agent
DG01940 Butyrophenone derivative
|
|---|
| Remark |
|
|---|
| Efficacy |
Antipsychotic, Neuroleptic, Dopamine D2 receptor antagonist |
|---|
| Comment |
Butyrophenone derivative
|
|---|
| Target |
|
|---|
| Pathway |
| hsa04080 | Neuroactive ligand-receptor interaction |
|
|---|
| Interaction |
|
|---|
| Structure map |
| map07031 | Antipsychotics - butyrophenones |
|
|---|
| Brite |
Anatomical Therapeutic Chemical (ATC) classification [BR:br08303]
N NERVOUS SYSTEM
N05 PSYCHOLEPTICS
N05A ANTIPSYCHOTICS
N05AD Butyrophenone derivatives
N05AD02 Trifluperidol
D02625 Trifluperidol (USAN/INN)
Drug groups [BR:br08330]
Neuropsychiatric agent
DG01478 Dopamine antagonist
DG01474 Dopamine D2-receptor antagonist
DG00886 Trifluperidol
D02625 Trifluperidol
DG03200 Antipsychotic agent
DG01940 Butyrophenone derivative
DG00886 Trifluperidol
D02625 Trifluperidol
Target-based classification of drugs [BR:br08310]
G Protein-coupled receptors
Rhodopsin family
Dopamine
DRD2
D02625 Trifluperidol (USAN/INN)
Drug groups [BR:br08330]
Neuropsychiatric agent
DG01478 Dopamine antagonist
DG01474 Dopamine D2-receptor antagonist
DG00886 Trifluperidol
DG03200 Antipsychotic agent
DG01940 Butyrophenone derivative
DG00886 Trifluperidol
|
|---|
| Other DBs |
|
|---|
| LinkDB |
|
|---|
| KCF data |
ATOM 29
1 C8x C 10.8500 -17.1500
2 C8y C 10.8500 -18.5500
3 C8x C 12.0624 -19.2500
4 C8x C 13.2749 -18.5500
5 C8y C 13.2749 -17.1500
6 C8x C 12.0624 -16.4500
7 C5a C 14.5124 -16.4500
8 C1b C 15.7249 -17.1500
9 C1b C 16.9373 -16.4500
10 C1b C 18.1497 -17.1500
11 N1y N 19.3622 -16.4500
12 C1x C 20.5953 -17.1622
13 C1x C 21.8079 -16.4624
14 C1z C 21.8081 -15.0624
15 C1x C 20.5750 -14.3502
16 C1x C 19.3624 -15.0500
17 C8y C 23.0499 -14.3456
18 C8x C 24.2491 -15.0383
19 C8y C 25.4617 -14.3385
20 C8x C 25.4620 -12.9385
21 C8x C 24.2627 -12.2458
22 C8x C 23.0502 -12.9456
23 C1d C 26.6927 -15.0495
24 X F 27.9051 -15.7495
25 X F 27.3927 -13.8371
26 X F 25.9927 -16.2620
27 O1a O 23.0205 -15.7624
28 O5a O 14.5186 -15.0503
29 X F 9.6376 -19.2500
BOND 31
1 1 2 2
2 2 3 1
3 3 4 2
4 4 5 1
5 5 6 2
6 1 6 1
7 5 7 1
8 7 8 1
9 8 9 1
10 9 10 1
11 10 11 1
12 11 12 1
13 12 13 1
14 13 14 1
15 14 15 1
16 15 16 1
17 11 16 1
18 14 17 1
19 17 18 2
20 18 19 1
21 19 20 2
22 20 21 1
23 21 22 2
24 17 22 1
25 19 23 1
26 23 24 1
27 23 25 1
28 23 26 1
29 14 27 1
30 7 28 2
31 2 29 1
|
|---|
