KEGG   DRUG: Indisetron hydrochloride
Entry
D02632                      Drug                                   
Name
Indisetron hydrochloride (JAN);
Sinseron (TN)
Formula
C17H23N5O. 2HCl
Exact mass
385.1436
Mol weight
386.3193
Structure
Class
Gastrointestinal agent
 DG01489  5-HT3-receptor antagonist
 DG01762  Antiemetic
Efficacy
Anti-emetic, Serotonin 5-HT3 receptor antagonist
Target
HTR3 [HSA:3359 9177 170572 200909 285242] [KO:K04819]
  Pathway
hsa04726  Serotonergic synapse
Interaction
Brite
Drug groups [BR:br08330]
 Gastrointestinal agent
  DG01489  5-HT3-receptor antagonist
   D02632  Indisetron hydrochloride
  DG01762  Antiemetic
   D02632  Indisetron hydrochloride
Target-based classification of drugs [BR:br08310]
 Ion channels
  Ligand-gated ion channels
   Serotonin
    HTR3
     D02632  Indisetron hydrochloride (JAN)
New drug approvals in Japan [br08318.html]
 Drugs with new active ingredients
  D02632
New drug approvals in the USA, Europe and Japan [br08328.html]
 Approval dates by FDA, EMA and PMDA
  D02632
Other DBs
CAS: 160472-97-9
PubChem: 17396802
LigandBox: D02632
NIKKAJI: J623.846G
LinkDB
KCF data

ATOM        25
            1   C1x C    11.7838  -16.9908
            2   C1x C    12.1119  -15.9591
            3   C1y C    12.9555  -16.7096
            4   C1y C    13.2836  -15.5379
            5   N1y N    12.0182  -14.2256
            6   C1x C    14.8302  -16.7096
            7   C1x C    14.5490  -15.5379
            8   C1y C    15.8613  -17.2720
            9   N1b N    16.9393  -18.1625
            10  C5a C    18.1579  -18.1625
            11  C8y C    18.7672  -17.0845
            12  O5a O    18.7672  -19.2873
            13  C1a C    11.2691  -13.0414
            14  N1y N    11.0138  -15.4284
            15  C1a C     9.9407  -14.4732
            16  C8y C    20.1672  -17.0845
            17  C8y C    20.5998  -15.7530
            18  N4x N    19.4672  -14.9301
            19  N5x N    18.3346  -15.7530
            20  C8x C    21.1040  -18.1249
            21  C8x C    22.4734  -17.8338
            22  C8x C    22.9060  -16.5023
            23  C8x C    21.9692  -15.4619
            24  X   Cl   25.9700  -16.8700
            25  X   Cl   25.9700  -16.8700
BOND        26
            1     1   3 1
            2     2   4 1
            3     3   5 1
            4     3   6 1
            5     4   7 1
            6     6   8 1
            7     8   9 1 #Down
            8     9  10 1
            9    10  11 1
            10   10  12 2
            11    4   5 1
            12    7   8 1
            13    5  13 1
            14    1  14 1
            15   14   2 1
            16   14  15 1
            17   11  16 1
            18   16  17 1
            19   17  18 1
            20   18  19 1
            21   11  19 2
            22   16  20 2
            23   20  21 1
            24   21  22 2
            25   22  23 1
            26   17  23 2
BRACKET     1    24.4300  -17.8500   24.4300  -15.8200
            1    26.6700  -15.8200   26.6700  -17.8500
            1  2
 ORIGINAL  1   26
 REPEAT    1   27

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