| Entry |
|
|---|
| Name |
Indisetron hydrochloride (JAN);
Sinseron (TN) |
|---|
| Formula |
C17H23N5O. 2HCl
|
|---|
| Exact mass |
385.1436
|
|---|
| Mol weight |
386.3193
|
|---|
| Structure |
|
|---|
| Class |
Gastrointestinal agent
DG01762 Antiemetic
Other
DG01489 5-HT3-receptor antagonist
|
|---|
| Remark |
| Therapeutic category: | 2391 |
|
|---|
| Efficacy |
Anti-emetic, Serotonin 5-HT3 receptor antagonist |
|---|
| Target |
|
|---|
| Pathway |
|
|---|
| Interaction |
|
|---|
| Brite |
Therapeutic category of drugs in Japan [BR:br08301]
2 Agents affecting individual organs
23 Digestive organ agents
239 Miscellaneous
2391 Antiemetics
D02632 Indisetron hydrochloride (JAN)
Target-based classification of drugs [BR:br08310]
Ion channels
Ligand-gated ion channels
Serotonin
HTR3
D02632 Indisetron hydrochloride (JAN)
New drug approvals in Japan [br08318.html]
Drugs with new active ingredients
D02632
New drug approvals in the USA, Europe and Japan [br08328.html]
Approval dates by FDA, EMA and PMDA
D02632
|
|---|
| Other DBs |
|
|---|
| LinkDB |
|
|---|
| KCF data |
ATOM 25
1 C1x C 11.7838 -16.9908
2 C1x C 12.1119 -15.9591
3 C1y C 12.9555 -16.7096
4 C1y C 13.2836 -15.5379
5 N1y N 12.0182 -14.2256
6 C1x C 14.8302 -16.7096
7 C1x C 14.5490 -15.5379
8 C1y C 15.8613 -17.2720
9 N1b N 16.9393 -18.1625
10 C5a C 18.1579 -18.1625
11 C8y C 18.7672 -17.0845
12 O5a O 18.7672 -19.2873
13 C1a C 11.2691 -13.0414
14 N1y N 11.0138 -15.4284
15 C1a C 9.9407 -14.4732
16 C8y C 20.1672 -17.0845
17 C8y C 20.5998 -15.7530
18 N4x N 19.4672 -14.9301
19 N5x N 18.3346 -15.7530
20 C8x C 21.1040 -18.1249
21 C8x C 22.4734 -17.8338
22 C8x C 22.9060 -16.5023
23 C8x C 21.9692 -15.4619
24 X Cl 25.9700 -16.8700
25 X Cl 25.9700 -16.8700
BOND 26
1 1 3 1
2 2 4 1
3 3 5 1
4 3 6 1
5 4 7 1
6 6 8 1
7 8 9 1 #Down
8 9 10 1
9 10 11 1
10 10 12 2
11 4 5 1
12 7 8 1
13 5 13 1
14 1 14 1
15 14 2 1
16 14 15 1
17 11 16 1
18 16 17 1
19 17 18 1
20 18 19 1
21 11 19 2
22 16 20 2
23 20 21 1
24 21 22 2
25 22 23 1
26 17 23 2
BRACKET 1 24.4300 -17.8500 24.4300 -15.8200
1 26.6700 -15.8200 26.6700 -17.8500
1 2
ORIGINAL 1 26
REPEAT 1 27
|
|---|
