KEGG   DRUG: Alglucerase
Entry
D02810                      Drug                                   

Name
Alglucerase (JAN/USAN/INN);
Ceredase (TN)
Formula
C2532H3854N672O711S16
Exact mass
55562.1608
Mol weight
55596.809
Sequence
ARPCIPKSFG YSSVVCVCNA TYCDSFDPPT FPALGTFSRY ESTRSGRRME LSMGPIQANH
TGTGLLLTLQ PEQKFQKVKG FGGAMTDAAA LNILALSPPA QNLLLKSYFS EEGIGYNIIR
VPMASCDFSI RTYTYADTPD DFQLHNFSLP EEDTKLKIPL IHRALQLAQR PVSLLASPWT
SPTWLKTNGA VNGKGSLKGQ PGDIYHQTWA RYFVKFLDAY AEHKLQFWAV TAENEPSAGL
LSGYPFQCLG FTPEHQRDFI ARDLGPTLAN STHHNVRLLM LDDQRLLLPH WAKVVLTDPE
AAKYVHGIAV HWYLDFLAPA KATLGETHRL FPNTMLFASE ACVGSKFWEQ SVRLGSWDRG
MQYSHSIITN LLYHVVGWTD WNLALNPEGG PNWVRNFVDS PIIVDITKDT FYKQPMFYHL
GHFSKFIPEG SQRVGLVASQ KNDLDAVALM HPDGSAVVVV LNRSSKDVPL TIKDPAVGFL
ETISPGYSIH TYLWRRQ
  Type
Peptide
Remark
ATC code: A16AB01
Efficacy
Lysosomal storage disease treatment, Enzyme replacement (glucocerebrosidase)
Comment
Enzyme replacement therapy product
Treatment of Gaucher disease
Target
GBA* [HSA_VAR:2629v1] [HSA:2629] [KO:K01201]
Brite
Anatomical Therapeutic Chemical (ATC) classification [BR:br08303]
 A ALIMENTARY TRACT AND METABOLISM
  A16 OTHER ALIMENTARY TRACT AND METABOLISM PRODUCTS
   A16A OTHER ALIMENTARY TRACT AND METABOLISM PRODUCTS
    A16AB Enzymes
     A16AB01 Alglucerase
      D02810  Alglucerase (JAN/USAN/INN)
Target-based classification of drugs [BR:br08310]
 Enzymes
  Hydrolases (EC3)
   Glycosidases
    GBA* [HSA_VAR:2629v1]
     D02810  Alglucerase (JAN/USAN/INN)
Other DBs
CAS: 143003-46-7
PubChem: 17396968
DrugBank: DB00088
LinkDB

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