| Entry |
|
|---|
| Name |
Angiotensin amide (USAN);
Angiotensinamide (INN) |
|---|
| Formula |
C49H70N14O11
|
|---|
| Exact mass |
1030.5348
|
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| Mol weight |
1031.17
|
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| Structure |
|
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| Simcomp |
|
|---|
| Sequence |
NRVYVHPF-NH2 |
|---|
| Type |
Peptide |
|---|
| Remark |
|
|---|
| Efficacy |
Vasoconstrictor, Angiotensin II receptor agonist |
|---|
| Comment |
Angiotensin analog
|
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| Target |
|
|---|
| Pathway |
| hsa04080 | Neuroactive ligand-receptor interaction |
| hsa04261 | Adrenergic signaling in cardiomyocytes |
| hsa04270 | Vascular smooth muscle contraction |
|
|---|
| Brite |
Anatomical Therapeutic Chemical (ATC) classification [BR:br08303]
C CARDIOVASCULAR SYSTEM
C01 CARDIAC THERAPY
C01C CARDIAC STIMULANTS EXCL. CARDIAC GLYCOSIDES
C01CX Other cardiac stimulants
C01CX06 Angiotensinamide
D02939 Angiotensin amide (USAN)
Target-based classification of drugs [BR:br08310]
G Protein-coupled receptors
Rhodopsin family
Angiotensin
AGTR1
D02939 Angiotensin amide (USAN)
AGTR2
D02939 Angiotensin amide (USAN)
|
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| Other DBs |
|
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| LinkDB |
|
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| KCF data |
ATOM 74
1 C1y C 37.8890 -24.1549
2 N1y N 36.5455 -24.1549
3 C1x C 36.1305 -25.4326
4 C1x C 37.2173 -26.2223
5 C1x C 38.3043 -25.4326
6 C5a C 39.0525 -23.4832
7 N1b N 40.2160 -24.1549
8 C1c C 41.3794 -23.4832
9 C1b C 42.5429 -24.1549
10 O5a O 39.0525 -22.1398
11 C6a C 41.3794 -22.1398
12 O6a O 42.5449 -21.4669
13 O6a O 40.2179 -21.4692
14 C8y C 43.7089 -23.4817
15 C8x C 44.8743 -24.1546
16 C8x C 46.0378 -23.4829
17 C8x C 46.0378 -22.1394
18 C8x C 44.8724 -21.4665
19 C8x C 43.7089 -22.1383
20 C5a C 35.3821 -23.4832
21 C1c C 34.2187 -24.1549
22 N1b N 33.0553 -23.4832
23 C5a C 31.8918 -24.1549
24 C1c C 30.7283 -23.4832
25 N1b N 29.5650 -24.1549
26 C5a C 28.4014 -23.4832
27 O5a O 35.3821 -22.1398
28 C1b C 34.2187 -27.5580
29 C8y C 35.3857 -28.2317
30 C8x C 35.5264 -29.5702
31 N5x N 36.8427 -29.8501
32 C8x C 37.5157 -28.6846
33 N4x N 36.6151 -27.6845
34 O5a O 31.8918 -25.5018
35 C1c C 30.7283 -21.4590
36 C1a C 31.8934 -20.7863
37 C1a C 29.5658 -20.7878
38 C1c C 27.2056 -24.1738
39 O5a O 28.4013 -22.1254
40 N1b N 26.0205 -23.4898
41 C5a C 24.8416 -24.1683
42 C1c C 23.6621 -23.4873
43 N1b N 22.4826 -24.1683
44 C5a C 21.3031 -23.4873
45 C1c C 20.1235 -24.1683
46 N1b N 18.9440 -23.4873
47 C5a C 17.7645 -24.1683
48 O5a O 24.8407 -25.5302
49 C1c C 23.6621 -21.5786
50 C1a C 22.4813 -20.8968
51 C1a C 24.8403 -20.8984
52 O5a O 21.3031 -22.1253
53 C1c C 16.5829 -23.4861
54 O5a O 17.7645 -25.5334
55 C1b C 15.3992 -24.1696
56 N1a N 16.5829 -22.1275
57 C5a C 14.2200 -23.4888
58 N1a N 13.0386 -24.1709
59 O5a O 14.2201 -22.1275
60 C1b C 20.1236 -25.5334
61 C1b C 21.3022 -26.2138
62 C1b C 21.3020 -27.5781
63 N1b N 22.4810 -28.2607
64 C2c C 22.4794 -29.6231
65 N1a N 23.6585 -30.3057
66 N2a N 21.3030 -30.3004
67 C1b C 27.2057 -25.8760
68 C8y C 28.3871 -26.5579
69 C8x C 28.3872 -27.9197
70 C8x C 29.5671 -28.6008
71 C8y C 30.7470 -27.9195
72 C8x C 30.7468 -26.5577
73 C8x C 29.5668 -25.8766
74 O1a O 31.9442 -28.6108
BOND 77
1 1 2 1
2 2 3 1
3 3 4 1
4 4 5 1
5 1 5 1
6 1 6 1
7 6 7 1
8 7 8 1
9 8 9 1
10 6 10 2
11 8 11 1
12 11 12 1
13 11 13 2
14 9 14 1
15 14 15 2
16 15 16 1
17 16 17 2
18 17 18 1
19 18 19 2
20 14 19 1
21 2 20 1
22 20 21 1
23 21 22 1
24 22 23 1
25 23 24 1
26 24 25 1
27 25 26 1
28 20 27 2
29 21 28 1
30 28 29 1
31 29 30 2
32 30 31 1
33 31 32 2
34 32 33 1
35 29 33 1
36 23 34 2
37 24 35 1
38 35 36 1
39 35 37 1
40 26 38 1
41 26 39 2
42 38 40 1
43 40 41 1
44 41 42 1
45 42 43 1
46 43 44 1
47 45 44 1
48 45 46 1
49 46 47 1
50 41 48 2
51 42 49 1
52 49 50 1
53 49 51 1
54 44 52 2
55 47 53 1
56 47 54 2
57 53 55 1
58 53 56 1
59 55 57 1
60 57 58 1
61 57 59 2
62 45 60 1
63 60 61 1
64 61 62 1
65 62 63 1
66 63 64 1
67 64 65 1
68 64 66 2
69 38 67 1
70 67 68 1
71 68 69 2
72 69 70 1
73 70 71 2
74 71 72 1
75 72 73 2
76 68 73 1
77 71 74 1
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