KEGG   DRUG: Antazoline phosphate
Entry
D02950                      Drug                                   
Name
Antazoline phosphate (USP)
Formula
C17H19N3. H3PO4
Exact mass
363.1348
Mol weight
363.35
Structure
Simcomp
Class
Anti-allergic agent
 DG01557  Histamine receptor antagonist
  DG01482  Histamine receptor H1 antagonist
Remark
ATC code: R01AC04 R06AX05
Chemical structure group: DG01037
Efficacy
Antiallergic, H1 receptor antagonist
Target
HRH1 [HSA:3269] [KO:K04149]
  Pathway
hsa04020  Calcium signaling pathway
hsa04080  Neuroactive ligand-receptor interaction
Interaction
Brite
Anatomical Therapeutic Chemical (ATC) classification [BR:br08303]
 R RESPIRATORY SYSTEM
  R01 NASAL PREPARATIONS
   R01A DECONGESTANTS AND OTHER NASAL PREPARATIONS FOR TOPICAL USE
    R01AC Antiallergic agents, excl. corticosteroids
     R01AC04 Antazoline
      D02950  Antazoline phosphate (USP)
  R06 ANTIHISTAMINES FOR SYSTEMIC USE
   R06A ANTIHISTAMINES FOR SYSTEMIC USE
    R06AX Other antihistamines for systemic use
     R06AX05 Antazoline
      D02950  Antazoline phosphate (USP)
Drug groups [BR:br08330]
 Anti-allergic agent
  DG01557  Histamine receptor antagonist
   DG01482  Histamine receptor H1 antagonist
    DG01037  Antazoline
     D02950  Antazoline phosphate
Target-based classification of drugs [BR:br08310]
 G Protein-coupled receptors
  Rhodopsin family
   Histamine
    HRH1
     D02950  Antazoline phosphate (USP)
Rx-to-OTC switch list in the USA [br08315.html]
 D02950
Drug groups [BR:br08330]
 Anti-allergic agent
  DG01557  Histamine receptor antagonist
   DG01482  Histamine receptor H1 antagonist
    DG01037  Antazoline
Other DBs
CAS: 154-68-7
PubChem: 17397107
LigandBox: D02950
NIKKAJI: J244.805J
LinkDB
KCF data

ATOM        25
            1   C8y C    13.4388  -14.4183
            2   C8x C    13.4388  -15.8182
            3   C8x C    14.6511  -16.5181
            4   C8y C    15.8634  -15.8182
            5   N1c N    15.8634  -14.4183
            6   C1b C    14.6511  -13.7184
            7   C8x C    17.0757  -16.5181
            8   N1x N    18.2879  -15.8182
            9   C2y C    18.2879  -14.4183
            10  C1b C    17.0757  -13.7184
            11  C8x C    12.2266  -13.7184
            12  C8x C    11.0142  -14.4183
            13  C8x C    11.0142  -15.8182
            14  C8x C    12.2266  -16.5181
            15  C8x C    14.6511  -17.9179
            16  C8x C    15.8634  -18.6178
            17  C8x C    17.0757  -17.9179
            18  C1x C    19.6193  -16.2507
            19  C1x C    20.4421  -15.1183
            20  N2x N    19.6193  -13.9858
            21  P1b P    24.9376  -15.6032
            22  O1c O    24.9304  -14.2024
            23  O1c O    26.3385  -15.6032
            24  O1c O    23.5367  -15.5961
            25  O1c O    24.9304  -17.0041
BOND        26
            1     1   2 1
            2     3   4 1
            3     4   5 1
            4     5   6 1
            5     1   6 1
            6     4   7 2
            7     8   9 1
            8     9  10 1
            9     5  10 1
            10    1  11 2
            11   11  12 1
            12   12  13 2
            13   13  14 1
            14   14   2 2
            15    3  15 2
            16   15  16 1
            17   16  17 2
            18   17   7 1
            19    8  18 1
            20   18  19 1
            21   19  20 1
            22    9  20 2
            23   21  22 2
            24   21  23 1
            25   21  24 1
            26   21  25 1

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